| Literature DB >> 35358168 |
Benjamin Rader, Autumn Gertz, A Danielle Iuliano, Matthew Gilmer, Laura Wronski, Christina M Astley, Kara Sewalk, Tanner J Varrelman, Jon Cohen, Rishika Parikh, Heather E Reese, Carrie Reed, John S Brownstein.
Abstract
COVID-19 testing provides information regarding exposure and transmission risks, guides preventative measures (e.g., if and when to start and end isolation and quarantine), identifies opportunities for appropriate treatments, and helps assess disease prevalence (1). At-home rapid COVID-19 antigen tests (at-home tests) are a convenient and accessible alternative to laboratory-based diagnostic nucleic acid amplification tests (NAATs) for SARS-CoV-2, the virus that causes COVID-19 (2-4). With the emergence of the SARS-CoV-2 B.1.617.2 (Delta) and B.1.1.529 (Omicron) variants in 2021, demand for at-home tests increased† (5). At-home tests are commonly used for school- or employer-mandated testing and for confirmation of SARS-CoV-2 infection in a COVID-19-like illness or following exposure (6). Mandated COVID-19 reporting requirements omit at-home tests, and there are no standard processes for test takers or manufacturers to share results with appropriate health officials (2). Therefore, with increased COVID-19 at-home test use, laboratory-based reporting systems might increasingly underreport the actual incidence of infection. Data from a cross-sectional, nonprobability-based online survey (August 23, 2021-March 12, 2022) of U.S. adults aged ≥18 years were used to estimate self-reported at-home test use over time, and by demographic characteristics, geography, symptoms/syndromes, and reasons for testing. From the Delta-predominant period (August 23-December 11, 2021) to the Omicron-predominant period (December 19, 2021-March 12, 2022)§ (7), at-home test use among respondents with self-reported COVID-19-like illness¶ more than tripled from 5.7% to 20.1%. The two most commonly reported reasons for testing among persons who used an at-home test were COVID-19 exposure (39.4%) and COVID-19-like symptoms (28.9%). At-home test use differed by race (e.g., self-identified as White [5.9%] versus self-identified as Black [2.8%]), age (adults aged 30-39 years [6.4%] versus adults aged ≥75 years [3.6%]), household income (>$150,000 [9.5%] versus $50,000-$74,999 [4.7%]), education (postgraduate degree [8.4%] versus high school or less [3.5%]), and geography (New England division [9.6%] versus West South Central division [3.7%]). COVID-19 testing, including at-home tests, along with prevention measures, such as quarantine and isolation when warranted, wearing a well-fitted mask when recommended after a positive test or known exposure, and staying up to date with vaccination,** can help reduce the spread of COVID-19. Further, providing reliable and low-cost or free at-home test kits to underserved populations with otherwise limited access to COVID-19 testing could assist with continued prevention efforts.Entities:
Mesh:
Year: 2022 PMID: 35358168 PMCID: PMC8979595 DOI: 10.15585/mmwr.mm7113e1
Source DB: PubMed Journal: MMWR Morb Mortal Wkly Rep ISSN: 0149-2195 Impact factor: 17.586
FIGUREProportion* of adults aged ≥18 years who reported at-home rapid COVID-19 antigen test use during the preceding 30 days — United States, August 23, 2021–March 12, 2022,
* 95% CI indicated by shading.
† B.1.617.2 (Delta)-predominant period = August 23–December 11, 2021; B.1.1.529 (Omicron)-predominant period = December 19, 2021–March 12, 2022 (end of study period).
§ Data aggregated by epidemiologic week to reduce noise related to daily estimates. Data points for each week displayed on the first day of respective MMWR week.
Percentage of survey respondents reporting at-home rapid COVID-19 antigen test use in the preceding 30 days among a cross-section of adults (N = 359,399*) aged ≥18 years, by demographic and other characteristics — United States, September 13, 2021–March 12, 2022
| Characteristic | Reported at-home test use, % (95% CI) | ||
|---|---|---|---|
| All survey respondents | Respondents reporting COVID-19 test¶ | Respondents reporting COVID-19–like illness symptoms** | |
|
| |||
| American Indian or Alaska Native | 3.3 (2.6–4.1) | 10.0 (8.0–12.4) | 7.8 (3.9–13.7) |
| Asian | 4.7 (4.3–5.1) | 18.3 (16.9–19.8) | 15.3 (11.1–20.3) |
| Black or African American | 2.8 (2.6–3.0) | 8.8 (8.2– 9.3) | 7.6 (5.9– 9.6) |
| Hispanic or Latino | 4.5 (4.2–4.7) | 14.1 (13.4–14.9) | 13.9 (11.9–16.0) |
| Native Hawaiian or other Pacific Islander | 3.5 (2.5–4.8) | 11.2 (8.0–15.2) | 8.0 (3.2–16.0) |
| White | 5.9 (5.8–6.1) | 22.8 (22.4–23.2) | 13.6 (12.9–14.4) |
| Multiracial | 5.4 (4.3–6.7) | 17.9 (14.4–21.9) | 20.1 (10.6–33.0) |
| Single other race | 4.6 (4.1–5.2) | 17.3 (15.5–19.3) | 11.8 (8.2–16.2) |
|
| |||
| Female | 5.4 (5.2–5.5) | 19.2 (18.8–19.6) | 12.8 (12.1–13.6) |
| Male | 4.9 (4.8–5.1) | 18.0 (17.5–18.5) | 13.2 (11.9–14.5) |
| Transgender or nonbinary | 6.5 (5.7–7.5) | 21.3 (18.7–24.0) | 17.7 (13.4–22.6) |
|
| |||
| High school or less | 3.5 (3.3–3.7) | 13.0 (12.4–13.6) | 9.7 (8.5–11.0) |
| Some college | 4.8 (4.6–4.9) | 17.3 (16.8–17.9) | 11.5 (10.5–12.5) |
| College or more | 7.2 (7.0–7.4) | 25.7 (25.1–26.4) | 18.8 (17.5–20.2) |
| Postgraduate degree | 8.4 (8.1–8.6) | 27.8 (27.2–28.5) | 20.3 (18.7–21.9) |
|
| |||
| 18–29 | 5.1 (4.9–5.4) | 16.9 (16.1–17.7) | 13.4 (11.6–15.3) |
| 30–39 | 6.4 (6.1–6.6) | 19.7 (19.0–20.5) | 15.3 (13.8–16.9) |
| 40–49 | 5.8 (5.6–6.0) | 19.3 (18.6–20.0) | 14.8 (13.4–16.3) |
| 50–64 | 4.9 (4.8–5.1) | 18.8 (18.3–19.3) | 11.8 (10.8–12.9) |
| 65–74 | 4.2 (4.0–4.4) | 19.4 (18.5–20.2) | 10.0 (8.5–11.7) |
| ≥75 | 3.6 (3.2–3.9) | 17.7 (16.1–19.3) | 12.4 (8.9–16.6) |
|
| |||
| <$15,000 | 3.1 (2.9–3.4) | 10.3 (9.6–11.1) | 6.9 (5.6– 8.4) |
| $15,000–$29,999 | 3.4 (3.2–3.7) | 12.2 (11.4–13.0) | 7.2 (5.9– 8.6) |
| $30,000–$49,999 | 4.0 (3.8–4.2) | 14.9 (14.1–15.7) | 11.3 (9.7–12.9) |
| $50,000–$74,999 | 4.7 (4.5–5.0) | 18.1 (17.3–18.9) | 13.1 (11.5–14.9) |
| $75,000–$99,999 | 5.6 (5.3–5.8) | 20.7 (19.7–21.6) | 16.2 (14.2–18.4) |
| $100,000–$150,000 | 6.8 (6.5–7.0) | 24.7 (23.8–25.6) | 20.0 (17.9–22.2) |
| >$150,000 | 9.5 (9.2–9.8) | 30.0 (29.2–30.9) | 25.4 (23.0–27.9) |
| Did not respond | 4.2 (3.9–4.5) | 17.5 (16.3–18.8) | 12.8 (10.0–16.2) |
|
| |||
| Unvaccinated | 3.5 (3.3–3.7) | 13.2 (12.5–13.8) | 8.5 (7.3– 9.8) |
| Partially vaccinated | 3.8 (3.5–4.1) | 12.9 (12.0–13.9) | 11.7 (9.5–14.1) |
| Fully vaccinated | 4.1 (4.0–4.3) | 15.7 (15.2–16.1) | 11.8 (10.8–12.8) |
| Fully vaccinated plus booster dose | 9.2 (9.0–9.5) | 30.0 (29.4–30.6) | 21.7 (20.2–23.2) |
| Did not respond | 3.7 (3.0–4.6) | 12.1 (9.7–14.9) | 8.1 (3.6–15.3) |
|
| |||
| Yes | 5.3 (5.2–5.5) | 17.9 (17.5–18.4) | 15.8 (14.6–16.9) |
| No | 6.8 (6.6–7.0) | 24.0 (23.4–24.7) | 17.7 (16.2–19.3) |
| Did not respond | 3.9 (3.8–4.1) | 15.8 (15.3–16.4) | 8.5 (7.6– 9.4) |
* Respondent numbers do not match total for complete survey because the data in this table are restricted to September 13, 2021–March 12, 2022, the time frame when all respondents (not just those who reported being symptomatic) were asked to report their at-home test use.
† The Rao-Scott chi-square test was used to test differences in proportion of respondents that reported having used an at-home test separately, across each of seven categorical variables (i.e., race, gender, age group, income, education, vaccination status, and being an essential worker). Differences were evaluated within each of three subpopulations of interest (i.e., all respondents, those who reported a COVID-19 test, and those who reported COVID19–like illness). All chi-square tests were statistically significant at the Bonferroni corrected p-value threshold of 0.0024 (0.05 over 21 comparisons performed).
§ Percentage of respondents who used an at-home test among the entire population of survey respondents, which includes those who used at-home tests, those who used other types of COVID-19 tests, and those who did not test for COVID-19.
¶ Percentage of persons who reported at-home test use among the portion of the surveyed population that reported being tested for COVID-19 including those who used at-home tests and those who used other types of COVID-19 tests.
** Percentage of persons who used an at-home test among the portion of the surveyed population that reported symptoms that were consistent with COVID-19–like illness.
†† Persons self-identified race/ethnicity based on a list that included U.S. Census Bureau categories for race and Hispanic ethnicity. Persons who selected multiple categories were considered multiracial. Persons who did not select Hispanic were assumed to be non-Hispanic.
Self-reported reasons for COVID-19 testing among adults aged ≥18 years who reported having received COVID-19 testing in the preceding 30 days, by test type — United States, September 13, 2021–March 12, 2022
| Reported reason for testing* | % Reporting (95% CI) | |
|---|---|---|
| Among those using at-home rapid COVID-19 antigen test (n = 18,578†) | Among those using other COVID-19 test (n = 80,851†) | |
| Exposed to COVID-19 | 39.4 (38.5–40.3) | 19.4 (19.0–19.7) |
| Had COVID-19 symptoms | 28.9 (28.1–29.7) | 16.7 (16.3–17.0) |
| Didn't feel well | 28.6 (27.8–29.4) | 7.0 (6.7–7.2) |
| To visit family | 17.0 (16.4–17.7) | 5.5 (5.3–5.7) |
| For work/school | 10.6 (10.1–11.3) | 17.4 (17.0–17.7) |
| Wanted to travel | 9.2 (8.7–9.8) | 23.2 (22.8–23.6) |
| Returning from travel | 8.8 (8.3–9.3) | 7.8 (7.5–8.0) |
| Doctor suggested | 3.7 (3.4–4.2) | 8.4 (8.2–8.7) |
| Surgery required testing | 2.0 (1.7–2.3) | 6.4 (6.2–6.6) |
| Other reported reason | 10.3 (9.8–10.9) | 13.0 (12.7–13.3) |
* Additional response options were added after the question was first implemented on the survey. These response categories were not analyzed because of incomplete data for the study period.
† Eighteen respondents that reported using an at-home test and 86 respondents who reported using other COVID-19 tests did not select any reasons for testing and were excluded from these counts and respective column percentages.