Literature DB >> 35354965

Polygenic scores in biomedical research.

Iftikhar J Kullo1, Cathryn M Lewis2, Michael Inouye3,4, Alicia R Martin5,6, Samuli Ripatti7,8,9,10, Nilanjan Chatterjee11.   

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Year:  2022        PMID： 35354965      PMCID： PMC9391275          DOI： 10.1038/s41576-022-00470-z

Source DB:  PubMed          Journal:  Nat Rev Genet        ISSN： 1471-0056            Impact factor:   59.581


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  56 in total

1.  2013 ACC/AHA guideline on the assessment of cardiovascular risk: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines.

Authors:  David C Goff; Donald M Lloyd-Jones; Glen Bennett; Sean Coady; Ralph B D'Agostino; Raymond Gibbons; Philip Greenland; Daniel T Lackland; Daniel Levy; Christopher J O'Donnell; Jennifer G Robinson; J Sanford Schwartz; Susan T Shero; Sidney C Smith; Paul Sorlie; Neil J Stone; Peter W F Wilson; Harmon S Jordan; Lev Nevo; Janusz Wnek; Jeffrey L Anderson; Jonathan L Halperin; Nancy M Albert; Biykem Bozkurt; Ralph G Brindis; Lesley H Curtis; David DeMets; Judith S Hochman; Richard J Kovacs; E Magnus Ohman; Susan J Pressler; Frank W Sellke; Win-Kuang Shen; Sidney C Smith; Gordon F Tomaselli
Journal:  Circulation       Date:  2013-11-12       Impact factor: 29.690

Review 2.  Clinical use of current polygenic risk scores may exacerbate health disparities.

Authors:  Alicia R Martin; Masahiro Kanai; Yoichiro Kamatani; Yukinori Okada; Benjamin M Neale; Mark J Daly
Journal:  Nat Genet       Date:  2019-03-29       Impact factor: 38.330

3.  Novel subgroups of adult-onset diabetes and their association with outcomes: a data-driven cluster analysis of six variables.

Authors:  Emma Ahlqvist; Petter Storm; Annemari Käräjämäki; Mats Martinell; Mozhgan Dorkhan; Annelie Carlsson; Petter Vikman; Rashmi B Prasad; Dina Mansour Aly; Peter Almgren; Ylva Wessman; Nael Shaat; Peter Spégel; Hindrik Mulder; Eero Lindholm; Olle Melander; Ola Hansson; Ulf Malmqvist; Åke Lernmark; Kaj Lahti; Tom Forsén; Tiinamaija Tuomi; Anders H Rosengren; Leif Groop
Journal:  Lancet Diabetes Endocrinol       Date:  2018-03-05       Impact factor: 32.069

4.  Penetrance and Pleiotropy of Polygenic Risk Scores for Schizophrenia in 106,160 Patients Across Four Health Care Systems.

Authors:  Amanda B Zheutlin; Jessica Dennis; Richard Karlsson Linnér; Arden Moscati; Nicole Restrepo; Peter Straub; Douglas Ruderfer; Victor M Castro; Chia-Yen Chen; Tian Ge; Laura M Huckins; Alexander Charney; H Lester Kirchner; Eli A Stahl; Christopher F Chabris; Lea K Davis; Jordan W Smoller
Journal:  Am J Psychiatry       Date:  2019-08-16       Impact factor: 18.112

Review 5.  A roadmap to increase diversity in genomic studies.

Authors:  Segun Fatumo; Tinashe Chikowore; Ananyo Choudhury; Muhammad Ayub; Alicia R Martin; Karoline Kuchenbaecker
Journal:  Nat Med       Date:  2022-02-10       Impact factor: 87.241

6.  Prospective evaluation of a breast-cancer risk model integrating classical risk factors and polygenic risk in 15 cohorts from six countries.

Authors:  Amber N Hurson; Parichoy Pal Choudhury; Chi Gao; Anika Hüsing; Mikael Eriksson; Min Shi; Michael E Jones; D Gareth R Evans; Roger L Milne; Mia M Gaudet; Celine M Vachon; Daniel I Chasman; Douglas F Easton; Marjanka K Schmidt; Peter Kraft; Montserrat Garcia-Closas; Nilanjan Chatterjee
Journal:  Int J Epidemiol       Date:  2021-03-23       Impact factor: 9.685

Review 7.  Responsible use of polygenic risk scores in the clinic: potential benefits, risks and gaps.

Authors: 
Journal:  Nat Med       Date:  2021-11-15       Impact factor: 87.241

8.  Combined Utility of 25 Disease and Risk Factor Polygenic Risk Scores for Stratifying Risk of All-Cause Mortality.

Authors:  Allison Meisner; Prosenjit Kundu; Yan Dora Zhang; Lauren V Lan; Sungwon Kim; Disha Ghandwani; Parichoy Pal Choudhury; Sonja I Berndt; Neal D Freedman; Montserrat Garcia-Closas; Nilanjan Chatterjee
Journal:  Am J Hum Genet       Date:  2020-08-05       Impact factor: 11.025

9.  Genetic risk, coronary heart disease events, and the clinical benefit of statin therapy: an analysis of primary and secondary prevention trials.

Authors:  J L Mega; N O Stitziel; S Kathiresan; M S Sabatine; J G Smith; D I Chasman; M Caulfield; J J Devlin; F Nordio; C Hyde; C P Cannon; F Sacks; N Poulter; P Sever; P M Ridker; E Braunwald; O Melander
Journal:  Lancet       Date:  2015-03-04       Impact factor: 79.321

10.  The use of polygenic risk scores in pre-implantation genetic testing: an unproven, unethical practice.

Authors:  Francesca Forzano; Olga Antonova; Angus Clarke; Guido de Wert; Sabine Hentze; Yalda Jamshidi; Yves Moreau; Markus Perola; Inga Prokopenko; Andrew Read; Alexandre Reymond; Vigdis Stefansdottir; Carla van El; Maurizio Genuardi
Journal:  Eur J Hum Genet       Date:  2021-12-17       Impact factor: 5.351
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  1 in total

Review 1.  Use of Polygenic Risk Scores for Coronary Heart Disease in Ancestrally Diverse Populations.

Authors:  Ozan Dikilitas; Daniel J Schaid; Catherine Tcheandjieu; Shoa L Clarke; Themistocles L Assimes; Iftikhar J Kullo
Journal:  Curr Cardiol Rep       Date:  2022-07-07       Impact factor: 3.955
  1 in total

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