Literature DB >> 35347049

Pressurized metered-dose inhalers and their impact on climate change.

Lee Fidler1, Samantha Green1, Kimberly Wintemute1.   

Abstract

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Year:  2022        PMID: 35347049      PMCID: PMC8967439          DOI: 10.1503/cmaj.211747

Source DB:  PubMed          Journal:  CMAJ        ISSN: 0820-3946            Impact factor:   8.262


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Pressurized metered-dose (pMDI) inhalers are an important contributor to greenhouse gas emissions

Hydrofluorocarbon propellants in pMDIs are responsible for roughly 0.03% of yearly global greenhouse gas emissions.1 Prescriptions for pMDIs represent about 3% of total health care–related emissions from the United Kingdom’s National Health Service.2 The carbon footprint from 1 pMDI (200 doses) is estimated as equivalent to a 290-km automobile ride.3 Reducing pMDI prescriptions when appropriate could have a meaningful environmental impact.

Alternative inhalers with lower carbon impact are available

Dry powder and soft mist inhalers, both available as rapid reliever and maintenance therapies, are commonly used in the treatment of asthma and chronic obstructive pulmonary disease. Dry powder and soft mist inhalers contribute a lower carbon dioxide equivalency (< 20 g CO2e per inhalation) than pMDIs (about 100 g CO2e per inhalation).1

Dry powder and soft mist inhalers are effective and can have advantages over pMDI prescription

Compared with pMDIs, alternative inhaler devices show similar efficacy and are often preferred by patients.4–6 The Canadian Thoracic Society guideline highlights reliever therapy with a budesonide-formoterol dry powder inhaler as an appropriate alternative to short-acting β-agonist pMDIs in select patients with asthma, including those with milder disease.7 Using shared decision-making, physicians should counsel on the benefits and disadvantages of various inhalers, including their impact on climate change. Resources for implementing changes in inhaler prescriptions (i.e., posters, electronic medical record tools, patient letters), cost comparison charts and criteria for appropriate patient selection are publicly available.3

Prescribing only medically indicated inhaler treatment could substantially reduce carbon emissions

One-third of patients labelled as having asthma do not have asthma on objective testing.8 In the absence of a confirmed diagnosis, avoiding unnecessary inhaler prescribing could substantially reduce emissions related to health systems.

Proper recycling and disposal of inhalers can reduce carbon dioxide emissions

Recycling inhalers through pharmacies as opposed to landfill disposal allows the reuse of plastic or aluminum components and reduces CO2 production.3
  5 in total

1.  A more sustainable NHS.

Authors:  Maria van Hove; Gillian Leng
Journal:  BMJ       Date:  2019-08-02

2.  Reevaluation of Diagnosis in Adults With Physician-Diagnosed Asthma.

Authors:  Shawn D Aaron; Katherine L Vandemheen; J Mark FitzGerald; Martha Ainslie; Samir Gupta; Catherine Lemière; Stephen K Field; R Andrew McIvor; Paul Hernandez; Irvin Mayers; Sunita Mulpuru; Gonzalo G Alvarez; Smita Pakhale; Ranjeeta Mallick; Louis-Philippe Boulet
Journal:  JAMA       Date:  2017-01-17       Impact factor: 56.272

Review 3.  Comparison of the effectiveness of inhaler devices in asthma and chronic obstructive airways disease: a systematic review of the literature.

Authors:  D Brocklebank; F Ram; J Wright; P Barry; C Cates; L Davies; G Douglas; M Muers; D Smith; J White
Journal:  Health Technol Assess       Date:  2001       Impact factor: 4.014

4.  Comparison of patient preference and ease of teaching inhaler technique for Pulmicort Turbuhaler versus pressurized metered-dose inhalers.

Authors:  Michael J Welch; Harold S Nelson; Gail Shapiro; George W Bensch; William N Sokol; Joseph A Smith; Bhash M Parasuraman
Journal:  J Aerosol Med       Date:  2004

Review 5.  Patients' perspectives and preferences in the choice of inhalers: the case for Respimat(®) or HandiHaler(®).

Authors:  Pieter Nicolaas Richard Dekhuijzen; Federico Lavorini; Omar S Usmani
Journal:  Patient Prefer Adherence       Date:  2016-08-18       Impact factor: 2.711

  5 in total

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