Literature DB >> 35345726

Descriptive Study of Patients With Upper Limb Amputation As Possible Candidates for a Hand Transplant in Medellín, Colombia.

Evert Armando Jiménez Cotes1, Adolfo Alejandro López Rios2, Vanesa Vásquez Sañudo3, Esteban Cardona González4.   

Abstract

Introduction The amputation of the upper limb, especially of the hand, is a serious trauma with significant functional and psychological impact. Treatment options include adaptation to the stump, use of prostheses, and composite tissue transplantation. Unfortunately, in Colombia, to date, there are no epidemiological data that characterize the sociodemographic and clinical variables of patients with upper limb amputation. Objective To describe the clinical and epidemiological characteristics of patients with upper limb amputation in two hospital institutions in the city of Medellín during the period 2018-2019 as a basis for developing a hand transplant program in Colombia. Methods A descriptive cross-sectional study was carried out where a total of 443 medical records were reviewed, of which eight records that met the inclusion criteria were identified. Variables such as age, etiology of amputation, level of amputation, comorbidities, complications, and rehabilitation process were analyzed. The information was collected in the REDCap program, and a descriptive analysis was carried out with the data obtained. Results From a sample of 443 amputee patients, eight were selected that met the inclusion criteria. There were 7/8 men (87%) aged 43 years. A total of 75% came from rural areas. In 3/8 patients, there was amputation of the dominant limb. The most common mechanisms were shear trauma and crushing in the context of an occupational accident. A total of 50% had a complete extra-hospital amputation, and reimplantation was not attempted in any of the cases. The most frequent levels of amputation were the proximal and distal third of the forearm. The longest follow-up time was 12 months. Only two patients mentioned the possibility of using a prosthesis during rehabilitation. Conclusions Three young patients were identified, without comorbidities, with amputation of the dominant limb in the context of an occupational accident and without the possibility of rehabilitation with prostheses who benefit from a possible future hand transplant. However, it is necessary to implement a composite tissue transplantation program and public health policies that allow this procedure to be performed in Colombia.
Copyright © 2022, Jiménez Cotes et al.

Entities:  

Keywords:  amputation; hand; hand injuries; hand transplant; upper extremity

Year:  2022        PMID: 35345726      PMCID: PMC8956491          DOI: 10.7759/cureus.22527

Source DB:  PubMed          Journal:  Cureus        ISSN: 2168-8184


  12 in total

1.  Characterisation and outcomes of upper extremity amputations.

Authors:  David J Tennent; Joseph C Wenke; Jessica C Rivera; Chad A Krueger
Journal:  Injury       Date:  2014-02-15       Impact factor: 2.586

Review 2.  Upper limb prosthesis use and abandonment: a survey of the last 25 years.

Authors:  Elaine A Biddiss; Tom T Chau
Journal:  Prosthet Orthot Int       Date:  2007-09       Impact factor: 1.895

Review 3.  Hand Transplantation: Current Status and Immunologic Obstacles.

Authors:  Seong Hyuk Park; Seok-Chan Eun; Sung Tack Kwon
Journal:  Exp Clin Transplant       Date:  2019-02       Impact factor: 0.945

Review 4.  Hand transplantation--a review.

Authors:  Brendan J MacKay; Elliot Nacke; Martin Posner
Journal:  Bull Hosp Jt Dis (2013)       Date:  2014

5.  Hand and upper extremity transplantation: an update of outcomes in the worldwide experience.

Authors:  Jaimie T Shores; Gerald Brandacher; W P Andrew Lee
Journal:  Plast Reconstr Surg       Date:  2015-02       Impact factor: 4.730

Review 6.  [Hand transplantation - fiction or reality?].

Authors:  Esther Vögelin
Journal:  Ther Umsch       Date:  2011-12

7.  Estimating the prevalence of limb loss in the United States: 2005 to 2050.

Authors:  Kathryn Ziegler-Graham; Ellen J MacKenzie; Patti L Ephraim; Thomas G Travison; Ron Brookmeyer
Journal:  Arch Phys Med Rehabil       Date:  2008-03       Impact factor: 3.966

8.  Left-hand dominance and hand trauma.

Authors:  J S Taras; M J Behrman; G G Degnan
Journal:  J Hand Surg Am       Date:  1995-11       Impact factor: 2.230

Review 9.  Hand Transplantation Versus Hand Prosthetics: Pros and Cons.

Authors:  S Salminger; A D Roche; A Sturma; J A Mayer; O C Aszmann
Journal:  Curr Surg Rep       Date:  2016-01-27

10.  Analysis of combat casualties admitted to the emergency department during the negotiation of the comprehensive Colombian process of peace.

Authors:  Carlos A Ordoñez; Ramiro Manzano Nunez; Michael W Parra; Juan Pablo Herrera; Maria Paula Naranjo; Sara Sofia Escobar; Marisol Badiel; Monica Morales; Cecibel Cevallos; Juan G Bayona; Alvaro Ignacio Sanchez; Juan Carlos Puyana; Alberto F García
Journal:  Colomb Med (Cali)       Date:  2017-12-30
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