| Literature DB >> 35344248 |
Shane S Kelly1, Xiang Ni2, Vivian Yuen2, Miles N Radford1, Ming Xian2.
Abstract
C-Nitrosothioformamide was demonstrated to be a donor template for dual release of HNO and COS triggered by a retro-Diels-Alder reaction. COS is an H2 S precursor in the presence of carbonic anhydrase. This process produces HNO and H2 S in a slow but steady manner. As such, the direct reaction between HNO and H2 S under this situation appears to be minor. This may provide a useful tool for studying the synergistic effects of HNO and H2 S.Entities:
Keywords: donors; hydrogen sulfide; nitric oxide; nitroxyl; retro-Diels Alder reaction
Mesh:
Substances:
Year: 2022 PMID: 35344248 PMCID: PMC9316844 DOI: 10.1002/cbic.202200101
Source DB: PubMed Journal: Chembiochem ISSN: 1439-4227 Impact factor: 3.461