Literature DB >> 18956051

Photoactivatable HNO-releasing compounds using the retro-Diels-Alder reaction.

Yusuke Adachi1, Hidehiko Nakagawa, Kazuya Matsuo, Takayoshi Suzuki, Naoki Miyata.   

Abstract

We synthesized hetero-Diels-Alder cycloadducts from acyl nitroso derivatives and 9,10-dimethylanthracene, to be photo-inducible HNO-releasing agents and found that introduction of conjugated nitroaromatic groups effectively enhanced the responsiveness of HNO release to UV-A irradiation; we confirmed photoinduced HNO formation by EPR and GCMS analysis.

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Year:  2008        PMID： 18956051     DOI： 10.1039/b811985f

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  7 in total

Review 1.  The emergence of nitroxyl (HNO) as a pharmacological agent.

Authors:  Christopher H Switzer; Wilmarie Flores-Santana; Daniele Mancardi; Sonia Donzelli; Debashree Basudhar; Lisa A Ridnour; Katrina M Miranda; Jon M Fukuto; Nazareno Paolocci; David A Wink
Journal:  Biochim Biophys Acta       Date:  2009-05-06

Review 2.  Recent advances in the chemical biology of nitroxyl (HNO) detection and generation.

Authors:  Zhengrui Miao; S Bruce King
Journal:  Nitric Oxide       Date:  2016-04-20       Impact factor: 4.427

Review 3.  The chemistry of nitroxyl-releasing compounds.

Authors:  Jenna F DuMond; S Bruce King
Journal:  Antioxid Redox Signal       Date:  2011-03-02       Impact factor: 8.401

Review 4.  Detection and quantification of nitric oxide-derived oxidants in biological systems.

Authors:  Matías N Möller; Natalia Rios; Madia Trujillo; Rafael Radi; Ana Denicola; Beatriz Alvarez
Journal:  J Biol Chem       Date:  2019-08-12       Impact factor: 5.157

5.  C-Nitrosothioformamide: A Donor Template for Dual Release of HNO and H2 S.

Authors:  Shane S Kelly; Xiang Ni; Vivian Yuen; Miles N Radford; Ming Xian
Journal:  Chembiochem       Date:  2022-04-07       Impact factor: 3.461

6.  Small-Molecule Inhibitors of the CD40-CD40L Costimulatory Protein-Protein Interaction.

Authors:  Jinshui Chen; Yun Song; Damir Bojadzic; Alejandro Tamayo-Garcia; Ana Marie Landin; Bonnie B Blomberg; Peter Buchwald
Journal:  J Med Chem       Date:  2017-10-25       Impact factor: 7.446

7.  Design, Synthesis, and Evaluation of Novel Immunomodulatory Small Molecules Targeting the CD40⁻CD154 Costimulatory Protein-Protein Interaction.

Authors:  Damir Bojadzic; Jinshui Chen; Oscar Alcazar; Peter Buchwald
Journal:  Molecules       Date:  2018-05-11       Impact factor: 4.411
  7 in total

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