Literature DB >> 35343053

Association of clinically significant weight loss with number of patient visits and months of attendance at an Australian multidisciplinary weight management clinic.

Juliana Chen1,2,3, Harpreet Kaur2, Joanna Jaques1,2, Zoe Rock2, Catherine M Dean4, Reginald V Lord1,5, Veronica Preda1,2.   

Abstract

Despite the obesity epidemic, there are relatively few multidisciplinary obesity services in Australia, and only limited data on the effectiveness of these services. The aim of this study was to evaluate the effectiveness of a university hospital-based weight management clinic-the 'Healthy Weight Clinic' in supporting patients to achieve clinically significant weight loss (≥5% reduction in body weight), weight maintenance, and changes in body composition. A retrospective review was conducted to determine weight and associated health outcomes in patients who attended an initial consultation in the first 2 years of the clinic-between March 2017 and March 2019. Follow up was at least 1 year for all patients. Patients who underwent bariatric surgery were excluded. Of 213 total patients, 172 patients attended more than one follow-up consultation for lifestyle modification. Mean weight change and percentage total weight change at last follow-up was -6.2 kg (SD 7.4) and - 6.0% (SD 6.9), respectively. For every additional clinic follow-up, there was 21.4% increased odds of achieving clinically significant weight loss, and for every additional month of follow-up, there was 10.1% increased odds of achieving clinically significant weight loss. Twenty percent of patients (34/172) maintained ≥5% of initial body weight loss for at least 1 year. Body composition measurements were also favourable, with significant changes in percentage skeletal muscle mass of +0.8% (SD 1.5) and in percentage fat mass by -1.4% (SD 3.2). Regular support in a structured holistic multidisciplinary obesity service enables patients to achieve clinically meaningful weight loss and improved skeletal muscle mass to body fat ratio, and maintain this loss for at least 1 year. Improved weight loss was associated with more patient visits and longer duration of attendance at the clinic.
© 2022 The Authors. Clinical Obesity published by John Wiley & Sons Ltd on behalf of World Obesity Federation.

Entities:  

Keywords:  dietetics; endocrinology; exercise physiology; follow-up; integrated care; interdisciplinary health team; obesity

Mesh:

Year:  2022        PMID: 35343053      PMCID: PMC9285583          DOI: 10.1111/cob.12520

Source DB:  PubMed          Journal:  Clin Obes        ISSN: 1758-8103


What is already known

Multidisciplinary interventions can lead to more effective weight loss outcomes for patients. There is considerable demand from both patients and other health professionals for specialist obesity services. Publicly funded weight management services across Australia are limited in number and are under‐resourced.

What this study adds

This study reports on the real‐life outcomes of patients attending a privately funded Australian university hospital‐based weight management clinic—the ‘Healthy Weight Clinic’. Through multidisciplinary care (endocrinology, dietetics and exercise physiology) patients were able to achieve clinically significant weight loss that is comparable to clinics in non‐Australian health systems. Higher engagement and follow‐up with the clinic were associated with greater weight loss.

INTRODUCTION

Overweight or obesity was estimated to affect 67% of Australian adults in 2017–2018. The adverse effects of overweight and obesity on risk of Type 2 diabetes, cardiovascular disease, certain cancers, all‐cause mortality, , and overall health and economic loss , , are well recognized. The risk of these obesity‐related comorbidities and chronic diseases can be reduced, however, by weight loss of 5%–10%. , , A systematic review with meta‐analysis of 34 randomized controlled trials of weight loss interventions for adults with obesity reported an 18% relative reduction in all‐cause mortality (relative risk 0.82, 95% CI: 0.71–0.95), with risk reduction also observed in 16 other RCTs for cardiovascular mortality and major adverse cardiac events. Even when patients achieve clinically significant weight loss, long‐term weight loss maintenance is challenging. A meta‐analysis of 29 weight loss interventions in the United States, with at least a 2‐year follow‐up period, found that over a quarter of lost weight had been regained at 1 year and 80% of lost weight was regained by 5 years. , At the individual level, a multidisciplinary team approach with input from medical, dietetic, exercise, and behavioural experts is recommended for chronic disease management, weight loss, and long‐term weight maintenance. , , , , , , , The multidisciplinary approach allows each team member to deliver regular and ongoing care and support within their specific expertise. This can motivate patients to make small achievable and sustainable changes across lifestyle factors, while enabling better communication and coordination of a consistent patient‐centred care plan. Compared to interventions that only address one behaviour, multicomponent interventions that target the combination of nutrition, physical activity, and behavioural modification have been found to promote greater weight loss. , In addition to their effectiveness, modelling has also shown that among women, multicomponent interventions are also more cost‐effective compared to routine primary care. Multidisciplinary teams also have a central role in providing holistic care to support long‐term weight loss maintenance. , Australian clinical practice guidelines strongly endorse the multidisciplinary approach and estimated the strength of evidence to support this as Grade A. However, it is recognized that there are inadequate obesity services in this country. A 2017 evaluation of multidisciplinary weight management services found only 16 public multidisciplinary weight management clinics in Australia. Most of these facilities were found to be under‐resourced in infrastructure, staffing numbers, access to multidisciplinary specialists, as well as having poor public funding for adjunctive pharmacotherapy and bariatric surgery. Recognizing this health service gap, we established the Healthy Weight Clinic (HWC) at Macquarie University in 2017 to increase access to multidisciplinary services. This study aimed to evaluate the outcomes of the HWC in supporting clinically significant weight loss and weight maintenance, and body composition changes. The findings contribute data for the effectiveness of a multidisciplinary weight management approach in an Australian academic private health care facility.

METHODS

Study design

This study was part of the Macquarie Health institutional audit and quality review initiative. Approval was granted by the Institutional Human Research Ethics Committee and Clinical Innovation and Audit Committee (CIAC MQCIAC2019002). This was a retrospective chart review of data collected from all patients with BMI ≥25 kg/m2 who attended at least one consultation at the HWC in the 2‐year period March 2017 to March 2019. Patient follow‐up data were collected until July 2020. Data were collected for outcomes from the lifestyle modification cohort of the clinic provided by the endocrinologist, dietitian, and exercise physiologist, including use of adjunctive pharmacotherapies. Patients who underwent bariatric surgery were excluded.

Study setting and multidisciplinary team consultations

The HWC at Macquarie University, Australia, is a privately funded teaching hospital‐affiliated specialist weight management clinic. The clinic uses a multidisciplinary model, engaging an interdisciplinary health care team of endocrinologists, dietitians, exercise physiologists, and bariatric surgical specialists to target physiology and behaviour change regarding diet and physical activity (Table S1). Operating out of one clinic allows for multi‐specialist collaboration and communication, with the aim of delivering a consistent evidence‐based medicine treatment plan and patient‐centred care. There are no specific inclusion or exclusion criteria for patients to engage with the HWC services, other than having a BMI ≥25 kg/m2. The typical pathway of care within the HWC and the specific strategies applied by each of the multidisciplinary care members are outlined in Figure S1. All patients consulted with the endocrinologist for medical assessment and management of metabolic and obesity‐related comorbidities. Appropriate referrals were made by the endocrinologist to additional medical specialities (most commonly to sleep and respiratory medicine, cardiology, rheumatology, and bariatric surgery). Adjunctive pharmacotherapies for weight loss were prescribed to patients as required. The Accredited Practising Dietitian and Accredited Exercise Physiologist, respectively, conducted comprehensive dietary and physical activity assessments with patients, including determining the socioecological factors influencing food and beverage intake, and physical activity. The dietitian also assessed the presence of disordered eating patterns and the patient's relationship with food according to the nutrition care process to facilitate delivery of medical nutrition therapy. The exercise physiologist conducted postural, mobility, and balance assessments to identify movement limitations or specific musculoskeletal issues. Team care members developed a consistent individualized intervention plan in negotiation with the patient. This plan encompassed education and behaviour counselling. This was achieved through motivational interviewing, SMART goal setting, and self‐monitoring using digital technologies such as nutrition apps and a wearable activity monitor. These technologies were used to encourage behaviour change with diet and nutrition and physical activity habits, build self‐efficacy, and facilitate adherence to diet and activity recommendations. Patients were typically reviewed on a four to six weekly basis with at least one of the HWC team. At these reviews, progress with SMART (specific, measurable, achievable, realistic, and time‐bound) goals and anthropometry measures were evaluated. Feedback was provided and adjustments to goals or new goals were developed, with engagement of further behavioural change techniques as necessary.

Data collection

Anthropometric measures (weight, waist circumference, and body composition) were collected as part of routine measurements taken by the dietitian, exercise physiologist, or endocrinologist at each consultation and recorded in the electronic medical record. Height was measured at baseline using a stadiometer calibrated at installation. Weight was measured with minimum clothing (including emptied pockets and without shoes) on bariatric digital weighing scales. Waist circumference was measured in centimetres at the umbilicus using a flexible plastic tape in the standing position. Patient body composition data were determined from bioimpedance spectroscopy analysis using the Impedimed SOZO device (Impedimed) to measure fat mass and skeletal muscle mass. Routine body composition measurements began in February 2018 upon availability of the SOZO machine in the clinic. Laboratory tests (fasting blood glucose, HbA1c, insulin resistance, lipid profile total cholesterol, HDL and LDL cholesterol, triglycerides) were also collected as part of routine medical care. Pre‐diabetes was defined as an HbA1c of 5.7%–6.4%, and Type 2 diabetes HbA1c ≥6.5% or a 75‐g oral glucose tolerance test consistent with diabetes, as per the American Diabetes Association guidelines. Data on disordered eating patterns were determined by the dietitian and extracted from the consultation notes and/or transcribed consultation summary letters.

Statistical analysis

Descriptive statistics were used to calculate patient baseline characteristics as well as changes in BMI classes. Independent t tests for continuous variables and chi‐square tests for categorical variables were used to assess any differences between patients who only attended the initial consultation compared to those who reattended the clinic. Paired t tests were used to compare weight and body composition changes by patients and assess differences between time points. Multiple regression was carried out to assess the relationship between weight loss and the number of patient visits to the clinic and length of clinic follow‐up and binary logistic regression analysis was used to determine the odds of achieving clinically significant weight loss. All statistical analyses were conducting using SPSS version 28 (IBM Corp.).

RESULTS

Baseline characteristics of HWC patients

A total of 239 patients attended the HWC in the 2‐year study period (March 2017–March 2019). Twenty‐six patients underwent bariatric surgery and were excluded from the study. The study cohort thus included 213 individuals who received lifestyle modification (with or without adjunctive pharmacotherapy). Demographic data for age, initial weight, and BMI are shown in Table 1. During the study and follow‐up period (up until June 2020), 172/213 (80.8%) patients attended the HWC more than once but 41 (19.2%) patients only attended the initial consultation. There were no significant differences in baseline characteristics between these two cohorts. The mean follow‐up period for those who reattended the clinic was 10.8 months (range: 1–39 months; SD 9.6). Of the 172 reattending patients, 140 (81.4%) utilized adjunct pharmacotherapies, (metformin, liraglutide, dulaglutide) as shown in Table 1. Data were collected prior to the availability of other glucagon‐like peptide‐1 receptor agonist (GLP‐1RA) therapies in the Australia (e.g., semaglutide and exenatide).
TABLE 1

Baseline characteristics of all patients, those who only attended the initial consultation and those who reattended the Healthy Weight Clinic

CharacteristicsAll patients (n = 213)Patients who only attended initial consultation (n = 41)Patients who reattended the clinic (n = 172)
Gender
Female143 (67.1%)29 (70.7%)114 (66.3%)
Male70 (32.9%)12 (29.3%)58 (33.7%)
Mean age (years)51.3 (SD 15.0)51 (SD 15.1)51.8 (SD 14.9)
Anthropometric data
Mean weight (kg)104.9 (SD 20.4)103.9 (SD 20.4)105.1 (SD 20.5)
Mean BMI (kg/m2)

37.3 (SD 6.8)

Male: 37.2 (SD 5.8)

Female: 37.3 (SD 7.3)

37.3 (SD 7.7)

Male: 34.9 (SD 5.7)

Female: 38.3 (SD 8.2)

37.2 (SD 6.6)

Male: 37.7 (SD 5.7)

Female: 37.3 (SD 7.3)

Mean excess weight (amount of weight over BMI 25 kg/m2) (kg)34.3 (SD 18.5)33.7 (SD 19.9)34.4 (SD 18.2)
Mean waist circumference (cm)

115.5 (SD 15.5)

Male: 125.0 (SD 15.8)

Female: 110.9 (SD 13.1)

114.7 (SD 12.3)

Male: 117.9 (SD 8.6)

Female: 113.3 (SD 13.7)

115.7 (SD 16.2)

Male: 126.5 (SD 16.6)

Female: 110.9 (SD 13.1)

Smoking status
Never146 (68.5%)28 (68.3%)118 (68.6%)
Quit ≥10 years19 (8.9%)1 (2.4%)18 (10.5%)
Quit <10 years16 (7.5%)1 (2.4%)15 (8.7%)
Current10 (4.7%)3 (7.3%)7 (4.1%)
Unknown22 (10.3%)8 (19.5%)14 (8.1%)
Medical history
Pre‐diabetes44 (20.7%)3 (7.3%)41 (23.8%)
Insulin resistance44 (20.7%)6 (14.6%)38 (22.1%)
Type 2 diabetes27 (12.7%)3 (7.3%)24 (14.0%)
Dyslipidaemia83 (39.0%)12 (29.3%)71 (41.3%)
Hypertension72 (33.8%)14 (34.1%)58 (33.7%)
Joint and mobility pain75 (35.2%)12 (29.3%)63 (36.6%)
Chronic back pain36 (16.9%)6 (14.6%)30 (17.4%)
Osteoarthritis27 (12.7%)4 (9.8%)23 (13.4%)
Obstructive sleep apnoea50 (23.5%)11 (26.8%)39 (22.7%)
Depression39 (18.3%)7 (17.1%)32 (18.6%)
Non‐alcoholic fatty liver disease (NAFLD)37 (17.4%)3 (7.3%)34 (19.8%)
Ischaemic heart disease9 (4.2%)2 (4.9%)7 (4.1%)
Polycystic ovarian syndrome31 (14.6%)3 (7.3%)28 (16.3%)
Eating pattern
Emotional/stress eating57 (26.8%)14 (34.1%)43 (25%)
Boredom/mindless eating15 (7.0%)2 (4.9%)13 (7.6%)
Meal skipping (no binge style habits)23 (10.8%)2 (4.9%)21 (12.2%)
Binge eating (triggered by meal skipping)18 (8.5%)3 (7.3%)15 (8.7%)
Binge eating (emotional or stress induced)19 (8.9%)6 (14.6%)13 (7.6%)
Laboratory tests
Mean HbA1c (% and mmol/mol)

5.80% (SD 1.1)

40 mmol/mol (SD −11.5)

5.80 (SD 1.4)

40 mmol/mol (SD −8.19)

5.80% (SD 1.1)

40 mmol/mol (SD −11.5)

Mean total cholesterol (mmol/L)5.11 (SD 1.17)5.50 (SD 1.0)5.06 (SD 1.2)
Mean high‐density lipoprotein (mmol/L)1.29 (SD 0.35)1.29 (SD 0.35)1.29 (SD 0.4)
Mean low‐density lipoprotein (mmol/L)3.11 (SD 1.09)2.79 (SD 1.0)3.17 (SD 1.1)
Mean triglycerides (mmol/L)1.50 (SD 0.71)1.51 (SD 0.64)1.50 (SD 0.7)
Pharmacotherapy (including in combination)
Metformin154 (72.3%)24 (58.5%)130 (75.6%)
Liraglutide69 (32.4%)11 (26.8%)58 (33.7%)
Dulaglutide7 (3.3%)0 (0%)7 (4.1%)
Duromine26 (12.2%)3 (7.3%)23 (13.4%)
Orlistat10 (4.7%)0 (0%)10 (5.8%)
Contrave2 (0.9%)0 (0%)2 (1.2%)
Length of clinic follow‐up
Did not return41 (19.2%)41 (100%)0 (0%)
1–2 months42 (19.7%)N/A42 (24.4%)
3–5 months30 (14.1%)N/A30 (17.4%)
6–8 months18 (8.5%)N/A18 (10.5%)
9–11 months21 (9.9%)N/A21 (12.2%)
12–18 months20 (9.4%)N/A20 (11.6%)
19–24 months22 (10.3%)N/A22 (12.8%)
25–36 months18 (8.5%)N/A18 (10.5%)
>36 months1 (0.5%)N/A1 (0.6%)
Number of patient visits to clinic
Only initial appointment41 (19.2%)41 (100%)0 (0%)
1–4 follow‐up visits47 (22.1%)N/A47 (27.3%)
5–9 follow‐up visits66 (31.9%)N/A66 (38.4%)
10–14 follow‐up visits33 (15.5%)N/A33 (19.2%)
15–19 follow‐up visits17 (8.0%)N/A17 (9.9%)
More than 20 follow‐up visits9 (4.2%)N/A9 (5.2%)
Baseline characteristics of all patients, those who only attended the initial consultation and those who reattended the Healthy Weight Clinic 37.3 (SD 6.8) Male: 37.2 (SD 5.8) Female: 37.3 (SD 7.3) 37.3 (SD 7.7) Male: 34.9 (SD 5.7) Female: 38.3 (SD 8.2) 37.2 (SD 6.6) Male: 37.7 (SD 5.7) Female: 37.3 (SD 7.3) 115.5 (SD 15.5) Male: 125.0 (SD 15.8) Female: 110.9 (SD 13.1) 114.7 (SD 12.3) Male: 117.9 (SD 8.6) Female: 113.3 (SD 13.7) 115.7 (SD 16.2) Male: 126.5 (SD 16.6) Female: 110.9 (SD 13.1) 5.80% (SD 1.1) 40 mmol/mol (SD −11.5) 5.80 (SD 1.4) 40 mmol/mol (SD −8.19) 5.80% (SD 1.1) 40 mmol/mol (SD −11.5)

Weight and body composition outcomes

Patients who reattended the clinic at least once achieved a mean weight change of −6.2 kg (SD 7.4) at last follow‐up, with a mean change in percentage body weight of −6.0% (SD 6.9) (Table 2). Consistent and significant weight loss from baseline was achieved between 3 to 24 months. Significant changes in weight were only observed between baseline and each time period and not between time points (p > .05).
TABLE 2

Weight and body composition changes for patients who reattended the clinic (n = 172)

OutcomeTime point
At last follow upBaseline to 3 months3–6 months6–9 months9–12 months12–24 months24–36 months
Weight outcomes
n 1721471119172303
Mean weight change, kg (SD)−6.2 (7.4)*−4.6 (4.5)*−1.4 (2.9)*−1.2 (2.7)*−0.8 (1.9)*−0.8 (5.6)−3.5 (15.2)
Mean BMI change, kg/m2 (SD)−2.3 (2.7)*−1.7 (1.6)*−0.5 (1.1)*−0.5 (1.0)*−0.3 (0.7)*−0.3 (2.0)−1.2 (5.8)
Mean percentage weight change, % (SD)−6.0 (6.9)*−4.3 (4.0)−1.3 (2.9)*−1.3 (2.8)−0.9 (2.1)−0.9 (5.5)−4.2 (19.4)
Waist circumference outcome
n 565345342351
Mean waist circumference change, cm (SD)−6.9 (7.7)*−3.9 (5.0)*−2.2 (3.6)*−1.3 (2.6)*−1.2 (2.4)*−5.1 (4.7)−1.3 (N/A)
Body composition outcomes
n 595955433880
Mean SMM change, kg (SD)−0.6 (1.2)*−0.4 (1.0)*−0.1 (0.9)−0.1 (0.9)−0.2 (0.9)−0.6 (1.0)N/A
Mean percentage SMM change, % (SD)0.8 (1.5)*0.5 (1.1)*0.4 (1.1)*0.2 (1.1)0.2 (1.0)−0.1 (1.1)N/A
Mean FM change, kg (SD)−3.7 (5.4)*−2.5 (3.6)*−1.5 (3.0)*−0.7 (2.7)−0.8 (2.2)*−0.9 (4.0)N/A
Mean percentage FM change, % (SD)−1.4 (3.2)*−0.9 (2.6)*−0.8 (2.4)*−0.2 (2.5)−0.4 (2.3)−0.5 (3.2)N/A

Note: *p value <.05 against baseline.

Abbreviations: FM, fat mass; N/A, not applicable; SMM, skeletal muscle mass.

Weight and body composition changes for patients who reattended the clinic (n = 172) Note: *p value <.05 against baseline. Abbreviations: FM, fat mass; N/A, not applicable; SMM, skeletal muscle mass. Weight loss of ≥5% of initial body weight was achieved by 51.2% of patients (n = 88/172) and 29.1% (n = 50/172) achieved between 5% and 9.9% weight loss (Table S2). At last follow‐up, seven patients (4.1%) achieved a healthy weight range BMI, and a shift in BMI classes by at least one classification group was achieved by a third of the patient cohort (31.9%; n = 55/172) (see Table S3 and Figure S2). Consistent significant reductions in waist circumferences were observed against baseline up until 9–12 months, with a waist circumference change at last follow‐up of −6.9 cm (SD 7.7). In those patients who had body composition measurements taken (n = 59), patients had a significant fat mass reduction of 3.7 kg (SD 5.4) at last follow‐up, equivalent to a −1.4% (SD 3.2) reduction in percentage fat mass as a proportion of body weight (Table 2). While absolute muscle mass had decreased by 0.6 kg (SD 1.2), overall proportion of skeletal muscle mass to body weight increased by 0.8% (SD 1.5) muscle mass.

Weight maintenance

Weight maintenance in the cohort occurred between 15 and 33 months (Figure S3). Further ongoing weight loss out to 36 months is shown but sample size at that time point was small (n = 3) due to the defined study period. Thirty‐four patients (19.8%) lost ≥5% of initial body weight and maintained it for at least 1 year.

Relationship between engagement with clinic and weight outcomes

Figure 1 is a graphical representation of the percentage total body weight change according to number of follow‐up visits to the clinic. Patients who engaged in 5–9 follow‐up visits with the clinic, achieved a mean weight loss of 5.7%, and a mean weight loss of 10.0% was achieved when patients attended between 10 and 14 follow‐up visits.
FIGURE 1

Percentage total body weight change according to the number of follow‐up visits with the clinic

Percentage total body weight change according to the number of follow‐up visits with the clinic From multiple regression analyses both the number of patient follow‐up visits with HWC clinicians, and the length of clinic follow‐up, significantly predicted percentage weight loss achieved by patients in our cohort (F(7163) = 6.26, p < .001, R 2 = .21). Age, gender, baseline weight, whether patients had a disordered eating pattern, and use of pharmacotherapies were not significantly associated with percentage total weight loss (p > .05). For every additional clinical encounter and extra month of follow up, there was further significant percentage weight loss achieved: 0.24% (SD 0.21, p = .02) for each additional clinic visit and 0.21% (SD 0.30, p < .001) for each additional month. Moreover, for every additional follow‐up visit with the clinic, there was 21.4% greater odds of being a patient who would achieve clinically significant (≥5%) weight loss (OR = 1.21, 95% CI: 1.12–1.31, p < .001). Attending each additional three follow‐up appointments was associated with a 78.9% increase in the odds of achieving clinically significant weight loss. Similarly, for each additional month of follow up, there was 10.1% greater odds of achieving ≥5% weight loss (OR = 1.10, 95% CI: 1.06–1.15, p < .001), meaning that with every additional 6 months of follow‐up with the clinic, there is a 78.1% increase in the likelihood of achieving clinically significant weight loss.

DISCUSSION

This study showed that lifestyle modification, with adjunctive pharmacotherapy when required, at an Australian multidisciplinary weight management clinic resulted in half of patients achieving clinically significant weight loss as well as beneficial changes in body composition that were maintained, for overall health benefits. More patient visits and longer duration of attendance at the clinic were also associated with greater odds of achieving clinically significant weight loss. The 6.2 kg mean weight loss and 6.0% reduction in percentage body weight reported here are comparable to other international multidisciplinary weight interventions that employed endocrinologists, dietitians, and exercise physiologists along with adjunctive pharmacotherapy. , , , , , , , , These studies reported weight change ranging from −3.5 to −9.5 kg at last follow‐up, and 24% to 51% of participants achieving clinically significant weight loss. Our results are also comparable to other Australian weight management clinics, such as the publicly funded Canberra Obesity Management Services that demonstrated a mean weight change of −6.2 kg with −5% change in mean percentage body weight. Clinically significant weight loss (≥5% of initial body weight) was achieved by a higher proportion of our patients (51.2%) compared to the Canberra clinic (36%). Our data reinforce the importance of regular and ongoing care in helping patients to achieve meaningful weight loss and can be used to advocate for lifestyle‐based weight management programs delivered in multidisciplinary clinics, with at least three follow‐up visits over a minimum 6‐month period to increase the odds of achieving clinically significant weight loss. These findings are consistent with other behavioural weight loss programs that indicate that greater adherence to attendance is associated with greater weight loss. , Similarly, long‐term weight maintenance could be attributed to expertise from the multidisciplinary HWC team who support and facilitate patient adherence through dietary, physical activity, psychological, behavioural and medical strategies necessary for long‐term weight loss success. , , In particular, this can include building habits of maintaining regularity of eating patterns, low‐caloric low‐fat diets, high levels of physical activity, and self‐monitoring of weight, aspects also addressed by the National Obesity Strategy for all Australians. According to systematic reviews, use of adjunctive pharmacotherapies in additional to behaviour‐based interventions have also been found to support greater weight loss, less weight regain, , and in promoting weight loss maintenance, compared to behavioural interventions alone. Interestingly, pharmacotherapy use was not a significant predictor for weight loss among our patient population. In part, this may have been due to the small proportion (18.6%) who did not utilize pharmacotherapies, but were in an action stage of change.

Strengths and limitations

This study provides a comprehensive description of real‐life clinical data linked to a well‐defined program structure. This study has been able to monitor weight changes longitudinally to examine trends over time, with successful outcomes for most patients in our data to date. Future studies can examine patient weight loss and maintenance for longer follow‐up periods, such as to 5 years, to support the benefit of privately funded multidisciplinary weight clinics such as this one. Evidence of benefit may help to counter efforts to reduce financial support for clinics like ours, which can be compared unfavourably by finance analysts to services such as those involving procedural specialists. It has been noted that interventions achieving long‐term weight management can also reduce health care use for up to 5 years after the intervention. Attrition rates are common in the clinical setting, likely exacerbated by patient expectations and access issues to clinical services, which has also been previously documented by the Canberra Obesity Management Services. With the recent release of Australia's National Obesity Strategy 2022–2032, the positive outcomes for patient care from our clinic could be used to support the strategy of developing and improving access to integrated models of care and referral pathways in order to prevent and manage unhealthy weight gain and obesity. Our data may be informative for health policy advisors and obesity lobby groups who can use clinical evidence to inform funding for program development.

CONCLUSIONS

We have demonstrated that clinically significant weight and body composition (fat mass and muscle mass) improvements are achievable through a multidisciplinary holistic clinic. The likelihood of patients achieving these benefits is associated with number of clinic visits and the number of months that patients continue to regularly attend the clinic. This can be valuable information to discuss with patients, encouraging them to persist with attendance and remain compliant with recommendations in order to achieve the set goals.

CONFLICTS OF INTEREST

Catherine M. Dean declares that she is a member of Macquarie University Council, which is an unpaid role for the governing body of the University. The other authors declare no conflicts of interest.

AUTHOR CONTRIBUTIONS

Juliana Chen, Joanna Jaques, and Veronica Preda contributed to study design and application. Data extraction was done by Zoe Rock, Juliana Chen, and Joanna Jaques. Harpreet Kaur and Juliana Chen analysed the data. Juliana Chen interpreted the results and drafted the first version of the manuscript. Zoe Rock, Joanna Jaques, Catherine M. Dean, Reginald V. Lord, and Veronica Preda contributed to interpretation of the results and revising the manuscript. All authors read and approved the final manuscript submitted. Appendix S1: Supporting Information Click here for additional data file.
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8.  Comparing the effectiveness of general dietary advice versus a very low energy diet in an obese outpatient population in Australia.

Authors:  Rebecca L Venchiarutti; Karen Byth; Jonathan L Marks; Ashwini Chand; Caron S Blumenthal
Journal:  Eat Weight Disord       Date:  2017-10-11       Impact factor: 4.652

Review 9.  The incidence of co-morbidities related to obesity and overweight: a systematic review and meta-analysis.

Authors:  Daphne P Guh; Wei Zhang; Nick Bansback; Zubin Amarsi; C Laird Birmingham; Aslam H Anis
Journal:  BMC Public Health       Date:  2009-03-25       Impact factor: 3.295

10.  Body-mass index and all-cause mortality: individual-participant-data meta-analysis of 239 prospective studies in four continents.

Authors:  Emanuele Di Angelantonio; Shilpa Bhupathiraju; David Wormser; Pei Gao; Stephen Kaptoge; Amy Berrington de Gonzalez; Benjamin Cairns; Rachel Huxley; Chandra Jackson; Grace Joshy; Sarah Lewington; JoAnn Manson; Neil Murphy; Alpa Patel; Jonathan Samet; Mark Woodward; Wei Zheng; Maigen Zhou; Narinder Bansal; Aurelio Barricarte; Brian Carter; James Cerhan; George Smith; Xianghua Fang; Oscar Franco; Jane Green; Jim Halsey; Janet Hildebrand; Keum Jung; Rosemary Korda; Dale McLerran; Steven Moore; Linda O'Keeffe; Ellie Paige; Anna Ramond; Gillian Reeves; Betsy Rolland; Carlotta Sacerdote; Naveed Sattar; Eleni Sofianopoulou; June Stevens; Michael Thun; Hirotsugu Ueshima; Ling Yang; Young Yun; Peter Willeit; Emily Banks; Valerie Beral; Zhengming Chen; Susan Gapstur; Marc Gunter; Patricia Hartge; Sun Jee; Tai-Hing Lam; Richard Peto; John Potter; Walter Willett; Simon Thompson; John Danesh; Frank Hu
Journal:  Lancet       Date:  2016-07-13       Impact factor: 79.321

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  2 in total

1.  The Impact of Multidisciplinary Weight Management on Body Weight and Body Mass Composition in Women with Breast Cancer Post-Adjuvant Chemotherapy: A Retrospective Chart Review.

Authors:  Vivien Nguyen; Juliana Chen; Reginald Lord; Veronica Preda
Journal:  Oncology       Date:  2022-04-11       Impact factor: 3.734

2.  Association of clinically significant weight loss with number of patient visits and months of attendance at an Australian multidisciplinary weight management clinic.

Authors:  Juliana Chen; Harpreet Kaur; Joanna Jaques; Zoe Rock; Catherine M Dean; Reginald V Lord; Veronica Preda
Journal:  Clin Obes       Date:  2022-03-27
  2 in total

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