Literature DB >> 35340829

Open redo thymectomy for a large recurrent thymoma in a patient with myasthenia gravis: a case report.

Christian Galata1, Stefan Porubsky2, Daniel Sebastian Dohle3, Ioannis Karampinis1, Davor Stamenovic1, Eric Dominic Roessner1.   

Abstract

Thoracoscopic and robotic approaches are becoming increasingly popular for thymoma surgery. Yet open thymectomy must still be mastered today, as it may be the only viable option in challenging cases. In this study, we report a case of an extended local recurrence of myasthenia gravis associated thymoma and a history of previous sternotomy. The mediastinal mass infiltrated the left upper lobe of the lung, the pericardium, and presumably the aortic arch. Although the standard for thymoma resection at our institution is the robotic approach, we performed primary open redo thymectomy in standby of cardiopulmonary bypass in this case. Intraoperatively, bleeding from the aortic arch occurred, which was promptly controlled due to the open approach and due to immediate availability of cardiopulmonary bypass. The patient was transferred to the normal ward on the first postoperative day, was treated according to fast-track principles and recovered well. The pathology revealed a WHO B2:B1 thymoma with negative resection margins. Thymectomy is recommended as the principal treatment for thymoma and is also advised in the case of recurrence. However, there is no evidence regarding the optimal surgical approach. Our case indicates that in the era of minimally invasive thymectomy, the decision to conduct open surgery is wise when the risk of serious bleeding is anticipated or adherence to oncologic principles is challenged by tumor size or growth pattern. 2022 Mediastinum. All rights reserved.

Entities:  

Keywords:  Recurrent thymoma; cardiopulmonary bypass; case report; open thymectomy

Year:  2022        PMID: 35340829      PMCID: PMC8841549          DOI: 10.21037/med-21-25

Source DB:  PubMed          Journal:  Mediastinum        ISSN: 2522-6711


  14 in total

1.  Addition of "near-miss" cases enhances a quality improvement conference.

Authors:  Michael H McCafferty; Hiram C Polk
Journal:  Arch Surg       Date:  2004-02

2.  Thymic epithelial tumours: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.

Authors:  N Girard; E Ruffini; A Marx; C Faivre-Finn; S Peters
Journal:  Ann Oncol       Date:  2015-09       Impact factor: 32.976

3.  Video-Assisted Thoracic Surgery Thymectomy Versus Sternotomy Thymectomy in Patients With Thymoma.

Authors:  Hiroyuki Agatsuma; Kazuo Yoshida; Ichiro Yoshino; Meinoshin Okumura; Masahiko Higashiyama; Kenji Suzuki; Masanori Tsuchida; Jitsuo Usuda; Hiroshi Niwa
Journal:  Ann Thorac Surg       Date:  2017-06-13       Impact factor: 4.330

4.  Recurrence of thymoma: analysis of clinicopathologic features, treatment, and outcome.

Authors:  E Ruffini; M Mancuso; A Oliaro; C Casadio; A Cavallo; R Cianci; P L Filosso; M Molinatti; C Porrello; N Cappello; G Maggi
Journal:  J Thorac Cardiovasc Surg       Date:  1997-01       Impact factor: 5.209

5.  Outcome of surgical treatment for recurrent thymic epithelial tumors with reference to world health organization histologic classification system.

Authors:  Meinoshin Okumura; Hiroyuki Shiono; Masayoshi Inoue; Hisaichi Tanaka; Hyun-Eng Yoon; Katsuhiro Nakagawa; Akihide Matsumura; Mitsunori Ohta; Keiji Iuchi; Hikaru Matsuda
Journal:  J Surg Oncol       Date:  2007-01-01       Impact factor: 3.454

6.  Recurrence of thymoma: clinicopathological features, re-operation, and outcome.

Authors:  M Haniuda; R Kondo; H Numanami; A Makiuchi; E Machida; J Amano
Journal:  J Surg Oncol       Date:  2001-11       Impact factor: 3.454

7.  Iterative Surgical Treatment for Repeated Recurrences After Complete Resection of Thymic Tumors.

Authors:  Alfonso Fiorelli; Antonio D'Andrilli; Camilla Vanni; Roberto Cascone; Marco Anile; Daniele Diso; Valentina Tassi; Jacopo Vannucci; Nicola Serra; Francesco Puma; Erino Angelo Rendina; Federico Venuta; Mario Santini
Journal:  Ann Thorac Surg       Date:  2016-11-05       Impact factor: 4.330

Review 8.  A systematic review of robotic versus open and video assisted thoracoscopic surgery (VATS) approaches for thymectomy.

Authors:  Katie E O'Sullivan; Usha S Kreaden; April E Hebert; Donna Eaton; Karen C Redmond
Journal:  Ann Cardiothorac Surg       Date:  2019-03

9.  The CARE Guidelines: Consensus-based Clinical Case Reporting Guideline Development.

Authors:  Joel J Gagnier; Gunver Kienle; Douglas G Altman; David Moher; Harold Sox; David Riley
Journal:  Glob Adv Health Med       Date:  2013-09

10.  Management and Long-Term Outcomes of Advanced Stage Thymoma in the United States.

Authors:  Rhami Khorfan; Ankit Bharat; David D Odell
Journal:  Ann Thorac Surg       Date:  2020-07-11       Impact factor: 4.330

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.