| Literature DB >> 35329249 |
Haidee Williams1, Rodney Ehrlich1, Stephen Barker2, Sophia Kisting-Cairncross1, Muzimkhulu Zungu3,4, Annalee Yassi2.
Abstract
In the wake of a large burden of silicosis and tuberculosis among ex-miners from the South African gold mining industry, several programmes have been engaged in examining and compensating those at risk of these diseases. Availability of a database from one such programme, the Q(h)ubeka Trust, provided an opportunity to examine the accuracy of length of service in predicting compensable silicosis, and the concordance between self-reported employment and that officially recorded. Compensable silicosis was determined by expert panels, with ILO profusion ≥1/0 as the threshold for compensability. Age, officially recorded and self-reported years of service, and years since first and last service of 3146 claimants for compensable silicosis were analysed. Self-reported and recorded service were moderately correlated (R = 0.66, 95% confidence interval 0.64-0.68), with a Bland-Altman plot showing no systematic bias. There was reasonably high agreement with 75% of the differences being less than two years. Logistic regression and receiver operating characteristic curve analysis were used to test prediction of compensable silicosis. There was little predictive difference between length of service on its own and a model adjusting for length of service, age, and years since last exposure. Predictive accuracy was moderate, with significant potential misclassification. Twenty percent of claimants with compensable silicosis had a length of service <10 years; in almost all these claims, the interval between last exposure and the claim was 10 years or more. In conclusion, self-reported service length in the absence of an official service record could be accepted in claims with compatible clinical findings. Length of service offers, at best, moderate predictive capability for silicosis. Relatively short service compensable silicosis, when combined with at least 10 years since last exposure, was not uncommon.Entities:
Keywords: South Africa; compensation; latency; length of service; silicosis
Mesh:
Substances:
Year: 2022 PMID: 35329249 PMCID: PMC8953429 DOI: 10.3390/ijerph19063562
Source DB: PubMed Journal: Int J Environ Res Public Health ISSN: 1660-4601 Impact factor: 3.390
Compensable and non-compensable silicosis claimants by length of service, age, and years since first and last exposure (N = 3146).
| Category | Compensable | Non-Compensable | Row Total | ||
|---|---|---|---|---|---|
| Years of service 1 |
| % |
| % |
|
| 0–2.9 | 50 | 32.1 | 106 | 67.9 | 156 |
| 3–5.9 | 101 | 31.8 | 217 | 68.2 | 318 |
| 6–9.9 | 197 | 39.7 | 299 | 60.3 | 496 |
| 10–14.9 | 285 | 51.3 | 271 | 48.7 | 556 |
| 15–19.9 | 453 | 63.2 | 264 | 36.8 | 717 |
| 20–24.9 | 262 | 68.6 | 120 | 31.4 | 382 |
| 25–29.9 | 170 | 74.2 | 59 | 25.8 | 229 |
| 30+ | 208 | 80.3 | 51 | 19.7 | 259 |
| Unknown | 10 | 30.3 | 23 | 69.7 | 33 |
| Mean years | 18.1 (95% CI 17.7, 18.5) | 12.6 (95% CI 12.2, 13.1) | |||
| Age (years) at claim |
| % |
| % |
|
| <50 | 2 | 9.5 | 19 | 90.5 | 21 |
| 50–59.9 | 259 | 45.0 | 317 | 55.0 | 576 |
| 60–69.9 | 823 | 55.6 | 657 | 44.4 | 1480 |
| 70–79.9 | 500 | 62.0 | 306 | 38.0 | 806 |
| 80+ | 152 | 62.8 | 90 | 37.2 | 242 |
| Unknown | 0 | 0.0 | 21 | 100.0 | 21 |
| Mean years | 67.5 (95% CI 67.1, 67.9) | 65.3 (95% CI 64.8, 65.7) | |||
| Years from start of service to claim |
| % |
| % | n |
| <20 | 4 | 20.0 | 16 | 80.0 | 20 |
| 20–29.9 | 65 | 46.8 | 74 | 53.2 | 139 |
| 30–39.9 | 728 | 51.8 | 678 | 48.2 | 1406 |
| 40–49.9 | 753 | 62.0 | 461 | 38.0 | 1214 |
| 50+ | 139 | 69.8 | 60 | 30.2 | 199 |
| Unknown | 47 | 28.0 | 121 | 72.0 | 168 |
| Mean years | 40.1 (95% CI 39.8, 40.4) | 38.1 (95% CI 37.8, 38.5) | |||
| Year from end of service to claim |
| % |
| % |
|
| <10 | 96 | 62.3 | 58 | 37.7 | 154 |
| 10–19.9 | 476 | 69.9 | 205 | 30.1 | 681 |
| 20–29.9 | 836 | 58.1 | 602 | 41.9 | 1438 |
| 30–39.9 | 260 | 40.2 | 386 | 59.8 | 646 |
| 40+ | 21 | 35.6 | 38 | 64.4 | 59 |
| Unknown | 47 | 28.0 | 121 | 72.0 | 168 |
| Mean years | 21.8 (95% CI 21.5, 22.2) | 25.2 (95% CI 24.8, 25.6) | |||
CI, confidence interval. 1 Officially recorded.
Figure 1Bland-Altman plot of officially recorded vs. self-reported length of mining service (n = 2379).
Correlation between covariates with 95% confidence intervals.
| Years Worked | Years from First Exposure to Claim | Years from Last Exposure to Claim | |
|---|---|---|---|
|
| 0.17 (0.13, 0.20) | 0.53 (0.50, 0.55) | 0.21 (0.18, 0.25) |
|
| 0.49 (0.46, 0.51) | −0.71 (−0.72, −0.69) | |
|
| 0.27 (0.24, 0.30) |
Figure 2Scatterplot of length of service against time since last exposure.
Unadjusted and adjusted predictive models of compensable silicosis.
| Variable (5-Year Increments) | Unadjusted Odds Ratio (95% CI) | Adjusted Model A- | Adjusted Model B- |
|---|---|---|---|
|
| 1.19 (1.14, 1.25) | 1.21 (1.14, 1.28) | 1.21 (1.14, 1.28) |
|
| 1.46 (1.39, 1.52) | 1.46 (1.38, 1.54) | 1.32 (1.22, 1.42) |
|
| 1.27 (1.20, 1.35) | 0.91 (0.84, 0.98) | - |
|
| 0.77 (0.74, 0.81) | - | 0.90 (0.84, 0.98) |
CI, confidence interval.
Claim outcome of workers with <10 years of service, stratified by years since last exposure.
| Compensable | Non-Compensable | ||||
|---|---|---|---|---|---|
| Years from Last Exposure to Claim | n | % (95% CI) | n | % (95% CI) | |
|
| 11 | 1 | 9.1% (0.5, 37.7) | 10 | 90.9% (62.3, 99.5) |
|
| 54 | 29 | 53.7% (40.6, 66.3) | 25 | 46.3% (33.7, 59.4) |
|
| 266 | 86 | 32.3% (27.0, 38.2) | 180 | 67.7% (61.8, 73.0) |
|
| 519 | 202 | 38.9% (34.8, 43.2) | 317 | 61.1% (56.8, 65.2) |
|
| 37 | 13 | 35.1% (21.8, 51.2) | 24 | 64.9% (48.8, 78.2) |
|
| 887 1 | 331 | 37.3% (34.2, 40.5) | 556 | 62.7% (59.5, 65.8) |
1 Excluding those with missing service records.
Area under the curve (AUC) of different predictive models.
| Predictor | AUC (95% CI) | Nagelkerke R2 |
|---|---|---|
| Unadjusted years of service | 0.681 (0.662, 0.700) | 0.122 |
| Unadjusted age | 0.583 (0.563, 0.603) | 0.026 |
| Unadjusted years from first exposure | 0.589 (0.568, 0.609) | 0.030 |
| Unadjusted years from last exposure | 0.625 (0.605, 0.646) | 0.055 |
| Adjusted model A | 0.690 (0.671, 0.709) | 0.135 |
| Adjusted model B | 0.690 (0.671, 0.709) | 0.135 |
Length of service threshold, sensitivity, and specificity based on receiver operating characteristic curve for compensable silicosis (N = 3146).
| Threshold | Sensitivity | Specificity | |
|---|---|---|---|
| Youden’s Index | 15.7 years | 59.8% | 68.3% |
|
| |||
| 90% | 6.5 years | 90% | 27.1% |
| 80% | 9.9 years | 80% | 44.6% |
| 70% | 13.1 years | 70% | 57.2% |
|
| |||
| 90% | 23.5 years | 25.3% | 90% |
| 80% | 18.8 years | 42.5% | 80% |
| 70% | 16.1 years | 57.8% | 70% |