Literature DB >> 35312956

Reducing research wastage by starting off on the right foot: optimally framing the research question.

Nancy E Mayo1,2, Nikki Ow3, Miho Asano4, Sorayya Askari5, Ruth Barclay6, Sabrina Figueiredo7, Melanie Hawkins8, Stanley Hum9, Mehmet Inceer10, Navaldeep Kaur11, Ayse Kuspinar12, Kedar K V Mate13, Ana Maria Moga10, Maryam Mozafarinia14.   

Abstract

PURPOSE: Strongly framed research questions are clear as to the population (P), the exposures or interventions (E/I), comparison groups (C), outcomes (O), time when relevant (T), and what the investigator wants to know. A solid framework sets up the measurement model, analysis, and anticipated results. The purpose of this study was to estimate the extent to which research questions in journals that focused on patient-reported outcome measures (PROM) and quality of life (QOL) are clear.
METHODS: All 440 research articles published in four PROM journals in 2020. excluding reviews, psychometric, and qualitative papers, were reviewed. Research questions were classified as: (i) adequately framed (ii) poorly framed; or (iii) unframed based on clarity criteria. Examples from each journal were presented and reframed to match results in the article.
RESULTS: Of 440 articles, 195 (44.3%) were classified as adequately framed; 230 (52.2%) as poorly framed; and 15 (3.4%) as unframed. There was heterogeneity across journals (Chi-square: 20.8; 6 df; p = 0.002). Only 29% were framed according to what the investigators wanted to know; 72% were framed like a "to do" list; and 6% were framed as a research agenda.
CONCLUSION: Almost half of the questions were poorly framed or unframed a practice that could contribute to research wastage. Even "adequately framed" questions rarely stated what they wanted to know a priori, increasing the risk of biased reporting. Researchers, reviewers, and editors should encourage the use established frameworks for research questions.
© 2022. The Author(s), under exclusive licence to Springer Nature Switzerland AG.

Entities:  

Keywords:  Methodology; Patient-reported outcome measures; Quality of life; Research question; Research wastage

Mesh:

Year:  2022        PMID: 35312956     DOI: 10.1007/s11136-022-03117-y

Source DB:  PubMed          Journal:  Qual Life Res        ISSN: 0962-9343            Impact factor:   3.440


  42 in total

1.  Reasons reviewers reject and accept manuscripts: the strengths and weaknesses in medical education reports.

Authors:  G Bordage
Journal:  Acad Med       Date:  2001-09       Impact factor: 6.893

Review 2.  Posing the research question: not so simple.

Authors:  Lehana Thabane; Tara Thomas; Chenglin Ye; James Paul
Journal:  Can J Anaesth       Date:  2008-12-24       Impact factor: 5.063

Review 3.  Avoidable waste in the production and reporting of research evidence.

Authors:  Iain Chalmers; Paul Glasziou
Journal:  Lancet       Date:  2009-06-12       Impact factor: 79.321

4.  Choosing the best research design for each question.

Authors:  D L Sackett; J E Wennberg
Journal:  BMJ       Date:  1997 Dec 20-27

5.  Guidelines for reading literature reviews.

Authors:  A D Oxman; G H Guyatt
Journal:  CMAJ       Date:  1988-04-15       Impact factor: 8.262

Review 6.  When is a research question not a research question?

Authors:  Nancy E Mayo; Miho Asano; Skye Pamela Barbic
Journal:  J Rehabil Med       Date:  2013-06       Impact factor: 2.912

7.  Scientific method: statistical errors.

Authors:  Regina Nuzzo
Journal:  Nature       Date:  2014-02-13       Impact factor: 49.962

8.  How to…write a good research question.

Authors:  Karen Mattick; Jenny Johnston; Anne de la Croix
Journal:  Clin Teach       Date:  2018-04

9.  The well-built clinical question: a key to evidence-based decisions.

Authors:  W S Richardson; M C Wilson; J Nishikawa; R S Hayward
Journal:  ACP J Club       Date:  1995 Nov-Dec

Review 10.  Conducting high-quality research in cardiothoracic surgical education: Recommendations from the Thoracic Education Cooperative Group.

Authors:  Mara B Antonoff; Stephanie Nguyen; Tom C Nguyen; David D Odell
Journal:  J Thorac Cardiovasc Surg       Date:  2018-10-19       Impact factor: 5.209

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