Literature DB >> 3530323

Purification and characterization of aminoimidazole ribonucleotide synthetase from Escherichia coli.

J L Schrimsher, F J Schendel, J Stubbe, J M Smith.   

Abstract

Aminoimidazole ribonucleotide (AIR) synthetase has been purified 15-fold to apparent homogeneity from Escherichia coli which contains a multicopy plasmid containing the purM, AIR synthetase, gene. The protein is a dimer composed of two identical subunits of Mr 38,500. The N-terminal sequence, amino acid composition, and steady-state kinetics of the protein have been determined. AIR synthetase has been shown to catalyze the transfer of the formyl oxygen of [18O]formylglycinamide ribonucleotide to Pi.

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Year:  1986        PMID: 3530323     DOI: 10.1021/bi00363a028

Source DB:  PubMed          Journal:  Biochemistry        ISSN: 0006-2960            Impact factor:   3.162


  10 in total

1.  Altered pathway routing in a class of Salmonella enterica serovar Typhimurium mutants defective in aminoimidazole ribonucleotide synthetase.

Authors:  J L Zilles; T J Kappock; J Stubbe; D M Downs
Journal:  J Bacteriol       Date:  2001-04       Impact factor: 3.490

2.  AIR synthetase in cowpea nodules: a single gene product targeted to two organelles?

Authors:  P M Smith; A J Mann; D E Goggin; C A Atkins
Journal:  Plant Mol Biol       Date:  1998-04       Impact factor: 4.076

3.  The genomes of polyextremophilic cyanidiales contain 1% horizontally transferred genes with diverse adaptive functions.

Authors:  Alessandro W Rossoni; Dana C Price; Mark Seger; Dagmar Lyska; Peter Lammers; Debashish Bhattacharya; Andreas Pm Weber
Journal:  Elife       Date:  2019-05-31       Impact factor: 8.140

4.  NaH-promoted one-pot synthesis of 5-amidoimidazoles from arylamines, carbon disulfide and isocyanides.

Authors:  Jie Luo; Yichan Zhang; Qiuxia Yan; Guo Yang; Yaohong Zhang; Hai Wang
Journal:  Mol Divers       Date:  2022-03-10       Impact factor: 2.943

5.  Reexamination of the Intracellular Localization of de Novo Purine Synthesis in Cowpea Nodules.

Authors:  C. A. Atkins; PMC. Smith; P. J. Storer
Journal:  Plant Physiol       Date:  1997-01       Impact factor: 8.340

6.  Quantitative assignment of reaction directionality in constraint-based models of metabolism: application to Escherichia coli.

Authors:  R M T Fleming; I Thiele; H P Nasheuer
Journal:  Biophys Chem       Date:  2009-09-01       Impact factor: 2.352

Review 7.  Structural biology of the purine biosynthetic pathway.

Authors:  Y Zhang; M Morar; S E Ealick
Journal:  Cell Mol Life Sci       Date:  2008-11       Impact factor: 9.261

8.  YcaO domains use ATP to activate amide backbones during peptide cyclodehydrations.

Authors:  Kyle L Dunbar; Joel O Melby; Douglas A Mitchell
Journal:  Nat Chem Biol       Date:  2012-04-22       Impact factor: 15.040

9.  Iterative Mechanism of Macrodiolide Formation in the Anticancer Compound Conglobatin.

Authors:  Yongjun Zhou; Annabel C Murphy; Markiyan Samborskyy; Patricia Prediger; Luiz Carlos Dias; Peter F Leadlay
Journal:  Chem Biol       Date:  2015-06-18

10.  Different Ways of Doing the Same: Variations in the Two Last Steps of the Purine Biosynthetic Pathway in Prokaryotes.

Authors:  Dennifier Costa Brandão Cruz; Lenon Lima Santana; Alexandre Siqueira Guedes; Jorge Teodoro de Souza; Phellippe Arthur Santos Marbach
Journal:  Genome Biol Evol       Date:  2019-04-01       Impact factor: 3.416

  10 in total

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