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Literature DB >> 35274751

Stem cells "aclymatise" to regenerate the blood system.

Livia E Lisi-Vega^1,2,3, Simón Méndez-Ferrer^1,2,3.

Abstract

How blood stem cells balance fate decisions between quiescence maintenance and differentiation during recovery from cancer treatment remains poorly understood. A recent study by Umemoto et al (2022) uncovers an unexpected linkage between metabolic and epigenetic regulation of haematopoiesis, suggesting new targets in haematopoietic regeneration, with possible implications in leukaemogenesis and therapy resistance.

Entities: Chemical

Mesh：

Year: 2022 PMID： 35274751 PMCID： PMC9016344 DOI： 10.15252/embj.2022110942

Source DB: PubMed Journal: EMBO J ISSN： 0261-4189 Impact factor: 14.012

11 in total

Review 1. Metabolic regulation of hematopoietic stem cells in the hypoxic niche.

Authors: Toshio Suda; Keiyo Takubo; Gregg L Semenza
Journal: Cell Stem Cell Date: 2011-10-04 Impact factor: 24.633

Review 2. Metabolic requirements for the maintenance of self-renewing stem cells.

Authors: Keisuke Ito; Toshio Suda
Journal: Nat Rev Mol Cell Biol Date: 2014-04 Impact factor: 94.444

3. Mitochondrial Potentiation Ameliorates Age-Related Heterogeneity in Hematopoietic Stem Cell Function.

Authors: Els Mansell; Valgardur Sigurdsson; Elitza Deltcheva; John Brown; Chela James; Kenichi Miharada; Shamit Soneji; Jonas Larsson; Tariq Enver
Journal: Cell Stem Cell Date: 2020-10-20 Impact factor: 24.633

4. ATP citrate lyase controls hematopoietic stem cell fate and supports bone marrow regeneration.

Authors: Terumasa Umemoto; Alban Johansson; Shah Adil Ishtiyaq Ahmad; Michihiro Hashimoto; Sho Kubota; Kenta Kikuchi; Haruki Odaka; Takumi Era; Daisuke Kurotaki; Goro Sashida; Toshio Suda
Journal: EMBO J Date: 2022-03-01 Impact factor: 14.012

5. Multilayer omics analysis reveals a non-classical retinoic acid signaling axis that regulates hematopoietic stem cell identity.

Authors: Katharina Schönberger; Nadine Obier; Mari Carmen Romero-Mulero; Pierre Cauchy; Julian Mess; Polina V Pavlovich; Yu Wei Zhang; Michael Mitterer; Jasmin Rettkowski; Maria-Eleni Lalioti; Karin Jäcklein; Jonathan D Curtis; Betty Féret; Pia Sommerkamp; Claudia Morganti; Keisuke Ito; Norbert B Ghyselinck; Eirini Trompouki; Joerg M Buescher; Erika L Pearce; Nina Cabezas-Wallscheid
Journal: Cell Stem Cell Date: 2021-10-26 Impact factor: 25.269

6. Proximity-Based Differential Single-Cell Analysis of the Niche to Identify Stem/Progenitor Cell Regulators.

Authors: Lev Silberstein; Kevin A Goncalves; Peter V Kharchenko; Raphael Turcotte; Youmna Kfoury; Francois Mercier; Ninib Baryawno; Nicolas Severe; Jacqueline Bachand; Joel A Spencer; Ani Papazian; Dongjun Lee; Brahmananda Reddy Chitteti; Edward F Srour; Jonathan Hoggatt; Tiffany Tate; Cristina Lo Celso; Noriaki Ono; Stephen Nutt; Jyrki Heino; Kalle Sipilä; Toshihiro Shioda; Masatake Osawa; Charles P Lin; Guo-Fu Hu; David T Scadden
Journal: Cell Stem Cell Date: 2016-08-11 Impact factor: 24.633

7. Stabilization of fatty acid synthesis enzyme acetyl-CoA carboxylase 1 suppresses acute myeloid leukemia development.

Authors: Hidenori Ito; Ikuko Nakamae; Jun-Ya Kato; Noriko Yoneda-Kato
Journal: J Clin Invest Date: 2021-06-15 Impact factor: 14.808

8. Leukemic Stem Cells Evade Chemotherapy by Metabolic Adaptation to an Adipose Tissue Niche.

Authors: Haobin Ye; Biniam Adane; Nabilah Khan; Timothy Sullivan; Mohammad Minhajuddin; Maura Gasparetto; Brett Stevens; Shanshan Pei; Marlene Balys; John M Ashton; Dwight J Klemm; Carolien M Woolthuis; Alec W Stranahan; Christopher Y Park; Craig T Jordan
Journal: Cell Stem Cell Date: 2016-06-30 Impact factor: 24.633