| Literature DB >> 35268258 |
Mei-Chi Hsu1, Wen-Chen Ouyang2,3,4.
Abstract
Moral cognition is an important and multidimensional, but often overlooked, determinant of violence. Very few interventions have systematically examined the role of moral reasoning, anger management and problem-solving together in violence. A randomized controlled trial was conducted to comprehensively evaluate the sustained effects of an integrated Moral Reasoning Development Intervention (MRDI) in the management of repetitive violence in schizophrenia. This study placed special emphasis on essential components related to moral reasoning and violence in patients with schizophrenia. Evaluations, including measures of violence, moral reasoning, ethical valuation and judgement, decision-making, conflict management style, and personality traits, were performed at baseline, end of intervention, and 1-month follow-up after intervention. We found that MRDI was superior to treatment-as-usual, in improving moral reasoning and related variables and violence outcomes (p < 0.05). In comparison with the treatment-as-usual group (n = 22), patients in the MRDI group (n = 21) showed improved levels of moral reasoning, with decreased levels of violent behaviors. The MRDI participants also experienced significantly greater improvements or changes (p < 0.05) in their ethical valuation and judgement, decision-making style and preferences, and conflict management style. Our findings provide important implications for risk assessment and violence management and prevention.Entities:
Keywords: conflict management style; decision-making; ethics; moral reasoning; personality traits; repetitive violence; schizophrenia
Year: 2022 PMID: 35268258 PMCID: PMC8911519 DOI: 10.3390/jcm11051169
Source DB: PubMed Journal: J Clin Med ISSN: 2077-0383 Impact factor: 4.241
Demographic and clinical characteristics and violence patterns across treatment groups at Baseline.
| No. (%) | Test |
| |||||
|---|---|---|---|---|---|---|---|
| MRDI | TAU | ||||||
| Age, mean ± SD, y | 42.24 ± 5.89 | 40.95 ± 4.01 | 0.839 | 0.406 | |||
| Age of onset of schizophrenia, mean ± SD, y | 22.10 ± 4.36 | 20.55 ± 3.87 | 1.232 | 0.225 | |||
| Gender | (male/female) | 16/5 | (76.2/23.8) | 17/5 | (77.3/22.7) | 0.007 | 0.933 |
| Education | Secondary school | 2 | (9.5) | 2 | (9.1) | 0.767 | 0.681 |
| High school | 14 | (66.7) | 17 | (77.3) | |||
| Junior college/college | 5 | (23.8) | 3 | (13.6) | |||
| Marriage status | Single | 16 | (76.2) | 18 | (81.8) | 0.428 | 0.934 |
| Married | 2 | (9.5) | 2 | (9.1) | |||
| Separated/divorced | 3 | (14.3) | 2 | (9.0) | |||
| Occupation | Unemployed | 19 | (90.5) | 19 | (86.4) | 0.177 | 0.674 |
| Employed | 2 | (9.5) | 3 | (13.6) | |||
| Religion | Buddhism/Taoism | 9 | (42.9) | 10 | (45.5) | 0.282 | 0.868 |
| Christian/others | 2 | (9.5) | 3 | (13.6) | |||
| None | 10 | (47.6) | 9 | (40.9) | |||
| Smoking | Yes | 9 | (42.9) | 11 | (50.0) | 0.220 | 0.639 |
| No | 12 | (57.1) | 11 | (50.0) | |||
| Level of smoking | 1–5 cig/day | 2 | (22.2) | 2 | (18.2) | 0.471 | 0.925 |
| 6–10 cig/day | 4 | (44.4) | 4 | (36.4) | |||
| 11–15 cig/day | 1 | (11.1) | 1 | (9.1) | |||
| 16–20 cig/day | 2 | (22.2) | 4 | (36.4) | |||
| Alcohol use | Yes | 4 | (19.0) | 5 | (22.7) | 0.088 | 0.767 |
| No | 17 | (81.0) | 17 | (77.3) | |||
| Drinking frequency | ≤1 time/month | 1 | (25.0) | 1 | (20.0) | 0.032 | 0.858 |
| 2–4 times/month | 3 | (75.0) | 4 | (80.0) | |||
| Family support | Strong | 2 | (9.5) | - | - | 2.288 | 0.515 |
| Moderate | 13 | (61.9) | 16 | (72.7) | |||
| Weak | 6 | (28.6) | 6 | (27.2) | |||
| Primary caregiver | Parent(s) | 13 | (61.9) | 10 | (45.5) | 1.302 | 0.729 |
| Sibling | 6 | (28.6) | 9 | (40.9) | |||
| Others | 2 | (9.6) | 3 | (13.6) | |||
| Violence patterns | Verbal violence | 19 | (90.5) | 17 | (77.3) | ||
| Physical violence | 12 | (57.1) | 10 | (455) | |||
| Aggression against property | 9 | (42.9) | 9 | (40.9) | |||
| Auto-aggression | 2 | (9.5) | 3 | (13.6) | |||
| Total scores, mean ± SD | 10.19 ± 7.64 | 8.45 ± 5.26 | 0.871 | 0.389 | |||
Treatment outcomes and continuous changes of violence across groups.
| Baseline | Post-Intervention | Follow-Up | ES | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MRDI | TAU | 95% CIs | MRDI | TAU | 95% CIs | MRDI | TAU | 95% CIs | |||||
| Anger with | 21.38 ± | 22.27 ± | −0.796, 0.431 | −3.155, 1.372 | 20.62 ± | 22.36 ± | −2.271, 0.028 | −3.296, −0.193 | 18.86 ± | 21.59 ± | −3.979, <0.001 | −4.121, −1.346 | |
| Verbal aggression | 14.29 ± | 15.36 ± | −1.149, 0.257 | −2.972, 0.816 | 13.29 ± | 15.50 ± | −2.559, 0.014 | −3.962, −0.467 | 13.62 ± | 16.14 ± | −3.740, <0.001 | −3.877, −1.158 | |
| Physical aggression | 27.19 ± | 28.64 ± | −1.093, 0.281 | −4.117, 1.225 | 23.24 ± | 26.73 ± | −4.255, <0.001 | −5.145, −1.833 | 21.29 ± | 24.86 ± | −4.079, <0.001 | −5.349, −1.807 | |
| Suspicion, hostility | 22.86 ± | 23.05 ± | −0.167, 0.868 | −2.460, 2.084 | 21.43 ± | 24.18 ± | −3.002, 0.005 | −4.605, −0.901 | 19.14 ± | 25.86 ± | −11.473, < 0.001 | −7.904, −5.538 | |
| Total | 85.24 ± | 89.32 ± | −1.052, 0.299 | −11.913, 3.753 | 77.90 ± | 88.09 ± | −3.797, <0.001 | −15.603, −4.769 | 72.95 ± | 88.45 ± | −8.128, <0.001 | −19.354, −11.650 | −2.47 |
Values are expressed as means ± standard deviations. a, examined by independent t-test between groups; MRDI, Integrated Moral Reasoning Development Intervention; TAU, treatment as usual. b, Follow-up between-group effect sizes (ES) (Cohen’s d). Positive d’s indicate increases in scores over time and negative d’s indicate decreases.
Treatment outcomes and continuous changes of moral reasoning and ethical valuation across groups.
| Baseline | Post-Intervention | Follow-Up | ES | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MRDI | TAU | 95% CIs | MRDI | TAU | 95% CIs | MRDI | TAU | 95% CIs | |||||
|
| 52.52 ± | 55.18 ± | −1.047, 0.301 | −7.786, 2.470 | 64.38 ± | 57.55 ± | 2.390, 0.022 | 1.059, 12.612 | 72.10 ± | 58.41 ± | 4.727, <0.001 | 6.485, 18.342 | 1.43 |
|
| |||||||||||||
| Justice | 3.64 ± | 3.39 ± | 1.218, 0.230 | −0.169, 0.682 | 4.69 ± | 4.05 ± | 3.219, 0.003 | 0.240, 1.050 | 5.14 ± | 4.09 ± | 4.565, <0.001 | 0.587, 1.517 | 1.39 |
| Deontology | 2.77 ± | 2.59 ± | 1.729, 0.091 | −0.031, 0.397 | 3.15 ± | 2.68 ± | 4.516, <0.001 | 0.261, 0.684 | 4.05 ± | 2.64 ± | 12.175, <0.001 | 1.177, 1.645 | 3.71 |
| Relativism | 3.27 ± | 3.33 ± | −0.511, 0.612 | −0.314, 0.188 | 4.11 ± | 3.70 ± | 2.396, 0.021 | 0.065, 0.763 | 5.17 ± | 3.58 ± | 9.530, <0.001 | 1.260, 1.938 | 2.91 |
| Utilitarianism | 2.62 ± | 2.84 ± | −1.159, 0.253 | −0.608, 0.165 | 3.43 ± | 3.00 ± | 2.030, 0.049 | 0.002, 0.855 | 3.98 ± | 3.11 ± | 3.606, <0.001 | 0.379, 1.346 | 1.12 |
| Egoism | 2.83 ± | 3.00 ± | −0.857, 0.397 | −0.559, 0.226 | 3.21 ± | 3.09 ± | 0.522, 0.604 | −0.354, 0.601 | 3.79 ± | 3.30 ± | 2.188, 0.034 | 0.038, 0.943 | 0.67 |
| Individual intention | 3.52 ± | 3.77 ± | −1.472, 0.149 | −0.590, 0.093 | 4.12 ± | 3.84 ± | 1.285, 0.206 | −0.159, 0.715 | 5.05 ± | 3.93 ± | 5.663, <0.001 | 0.718, 1.514 | 1.74 |
| Peers intention | 4.14 ± | 4.23 ± | −0.502, 0.618 | −0.424, 0.255 | 4.62 ± | 4.36 ± | 1.338, 0.188 | −0.130, 0.641 | 4.62 ± | 4.59 ± | 0.131, 0.896 | −0.405, 0.461 | |
| Ethical awareness | 3.24 ± | 3.36 ± | −0.551, 0.585 | −0.586, 0.335 | 4.14 ± | 3.41 ± | 3.027, 0.004 | 0.244, 1.223 | 4.90 ± | 3.77 ± | 3.772, <0.001 | 0.526, 1.738 | 1.15 |
Values are expressed as means ± standard deviations. a: Examined by independent t-test between groups. b, Follow-up between-group effect sizes (ES) (Cohen’s d). Positive d’s indicate increases in scores over time and negative d’s indicate decreases. Words in bold represent the outcome measures. Words that are not in bold represent the subscales of an outcome measure.
Treatment outcomes and continuous changes of reasoning and thinking styles across groups.
| Baseline | Post-Intervention | Follow-Up | ES | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MRDI | TAU | 95% CIs | MRDI | TAU | 95% CIs | MRDI | TAU | 95% CIs | |||||
|
| 5.92 ± | 6.12 ± | −1.672, 0.102 | −0.439, 0.041 | 6.94 ± | 6.00 ± | 7.828, <0.001 | 0.700, 1.186 | 7.72 ± | 6.17 ± | 12.594, <0.001 | 1.302, 1.800 | 3.8 |
|
| 7.66 ± | 7.59 ± | 0.622, 0.537 | −0.159, 0.300 | 7.19 ± | 7.39 ± | −1.759, 0.086 | −0.431, 0.030 | 6.55 ± | 7.15 ± | −4.233, <0.001 | −0.876, −0.310 | −1.31 |
| Rational Ability | 2.91 ± | 3.01 ± | −1.232, 0.225 | −0.263, 0.064 | 3.47 ± | 2.85 ± | 6.673, <0.001 | 0.430,0 0.803 | 3.96 ± | 3.16 ± | 4.616, <0.001 | 0.452, 1.154 | |
| Rational Engagement | 3.01 ± | 3.11 ± | −1.281, 0.208 | −0.256, 0.057 | 3.48 ± | 3.15 ± | 3.931, <0.001 | 0.159, 0.494 | 3.76 ± | 3.18 ± | 7.570, <0.001 | 0.422, 0.729 | |
| Experiential Ability | 3.96 ± | 3.83 ± | 1.534, 0.133 | −0.043, 0.312 | 3.68 ± | 3.88 ± | −2.484, 0.017 | −0.356, −0.037 | 3.34 ± | 3.71 ± | −3.502, <0.001 | −0.585, −0.157 | |
| Experiential Engagement | 3.70 ± | 3.76 ± | −0.824, 0.414 | −0.220, 0.093 | 3.50 ± | 3.51 ± | −0.061, 0.952 | −0.147, 0.139 | 3.22 ± | 3.43 ± | −2.850, 0.007 | −0.355, −0.061 | |
Values are expressed as means ± standard deviations. a: Examined by independent t-test between groups. b, Follow-up between-group effect sizes (ES) (Cohen’s d). Positive d’s indicate increases in scores over time and negative d’s indicate decreases. Words in bold represent the outcome measures. Words that are not in bold represent the subscales of an outcome measure.
Treatment outcomes and continuous changes of conflict management style across groups.
| Baseline | Post-Intervention | Follow-Up | ES | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MRDI | TAU | 95% CIs | MRDI | TAU | 95% CIs | MRDI | TAU | 95% CIs | |||||
| Integrating | 1.82 ± | 1.87 ± | −0.672, 0.505 | −0.188, 0.094 | 1.94 ± | 1.89 ± | 0.603, 0.550 | −0.116, 0.215 | 1.90 ± | 1.88 ± | 0.184, 0.855 | −0.151, 0.181 | |
| Obliging | 1.99 ± | 1.89 ± | 1.037, 0.306 | −0.093, 0.289 | 2.08 ± | 1.91 ± | 1.924, 0.061 | −0.008, 0.349 | 2.07 ± | 1.96 ± | 1.468, 0.150 | −0.041, 0.260 | |
| Dominating | 3.43 ± | 3.33 ± | 0.991, 0.327 | −0.105, 0.309 | 3.03 ± | 3.29 ± | −2.221, 0.032 | −0.482, −0.022 | 2.60 ± | 3.18 ± | −5.625, <0.001 | −0.790, −0.372 | −1.72 |
| Avoiding | 3.65 ± | 3.53 ± | 0.749, 0.458 | −0.217, 0.474 | 3.01 ± | 3.37 ± | −2.209, 0.033 | −0.694, −0.031 | 2.74 ± | 3.22 ± | −3.108, 0.003 | −0.793, −0.168 | −0.96 |
| Compromising | 2.04 ± | 1.90 ± | 1.639, 0.109 | −0.032, 0.309 | 2.88 ± | 2.15 ± | 4.464, <0.001 | 0.395, 1.048 | 3.42 ± | 2.13 ± | 7.006, <0.001 | 0.919, 1.664 | 2.12 |
Values are expressed as means ± standard deviations. a: Examined by independent t-test between groups. b, Follow-up between-group effect sizes (ES) (Cohen’s d). Positive d’s indicate increases in scores over time and negative d’s indicate decreases.
The difference of personality traits from baseline to endpoint. Follow original version.
| Test Statistics a | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MRDI | TAU | MRDI vs. TAU | MRDI vs. TAU | |||||||||
| T1 | T2 | T3 | T1 | T2 | T3 | T1 | T2 | T3 | T1 | T2 | T3 | |
| Emotional Stability | 6.00 ± | 5.00 ± | 4.50 ± | 5.91 ± | 5.73 ± | 5.52 ± | 0.239 | −2.024 | −3.157 | 0.812 | 0.049 | 0.003 |
| Conscientiousness | 2.50 ± | 2.93 ± | 3.29 ± | 2.39 ± | 2.52 ± | 2.64 ± | 0.820 | 2.208 | 2.760 | 0.417 | 0.033 | 0.009 |
| Openness To Experience | 2.88 ± | 3.50 ± | 4.02 ± | 2.70 ± | 2.77 ± | 2.86 ± | 0.947 | 3.302 | 4.746 | 0.349 | 0.002 | 0.000 |
| Extraversion | 2.79 ± | 2.83 ± | 3.00 ± | 2.68 ± | 2.64 ± | 2.82 ± | 0.603 | 1.157 | 1.163 | 0.550 | 0.254 | 0.252 |
| Agreeableness | 3.00 ± | 3.95 ± | 4.45 ± | 2.84 ± | 3.05 ± | 3.11 ± | 0.817 | 4.114 | 5.745 | 0.419 | <0.001 | <0.001 |
Values are expressed as means ± standard deviations. a: Examined by independent t-test between groups.
Effects of the integrated Moral Reasoning Development Intervention on study outcomes.
| Group (Inter-Group) | Time (within) Effect b | Interaction of Group and Time (Intervention Effect) c | ||||
|---|---|---|---|---|---|---|
| F |
| F |
| F |
| |
|
| 25.026 | <0.001 | 9.539 | 0.004 | 7.197 | 0.010 |
|
| 6.417 | 0.015 | 42.325 | <0.001 | 16.592 | <0.001 |
|
| ||||||
| Justice | 20.632 | <0.001 | 53.751 | <0.001 | 6.998 | 0.012 |
| Deontology | 81.638 | <0.001 | 70.874 | <0.001 | 61.443 | <0.001 |
| Relativism | 32.478 | <0.001 | 112.379 | <0.001 | 67.358 | <0.001 |
| Utilitarianism | 6.018 | 0.019 | 30.446 | <0.001 | 13.478 | <0.001 |
| Egoism | 0.845 | 0.363 | 23.031 | <0.001 | 6.383 | 0.015 |
|
| ||||||
| Rational | 61.009 | <0.001 | 141.016 | <0.001 | 127.430 | <0.001 |
| Experiential | 8.061 | 0.007 | 64.635 | <0.001 | 11.923 | <0.001 |
|
| ||||||
| Integrating | 0.006 | 0.938 | 5.046 | 0.030 | 1.907 | 0.175 |
| Obliging | 2.868 | 0.098 | 3.276 | 0.078 | .016 | 0.899 |
| Dominating | 8.404 | 0.006 | 52.907 | <0.001 | 25.088 | <0.001 |
| Avoiding | 2.592 | 0.115 | 72.228 | <0.001 | 18.164 | <0.001 |
| Compromising | 38.585 | <0.001 | 67.253 | <0.001 | 34.609 | <0.001 |
a Reference: control group. b Reference: baseline values. c Reference: baseline values of control group. Words in bold represent the outcome measures. Words that are not in bold represent the subscales of an outcome measure.