Literature DB >> 35241557

Comparison of Postoperative and Oncologic Outcomes in Laparoscopic and Open Right Colectomy for Colon Cancer: A 5-year Experience.

Effrosyni Stavrou1, Nikolaos Tzanakis2, Eleftherios Spartalis3, Dimitrios Patsouras3, Konstantinos Georgiou3, Georgios Tsourouflis3, Dimitrios Dimitroulis3, Nikolaos Nikiteas3.   

Abstract

BACKGROUND/AIM: Laparoscopic colectomy is a procedure which is being performed for three decades and is gaining popularity continuously over the traditional open colectomy. This study was conducted in order to compare postoperative and oncologic results based on several factors in laparoscopic and open right colectomy for right colon cancer. PATIENTS AND METHODS: This is a retrospective study of right colectomy at a single institution from 2015 until 2020. The factors that were studied included postoperative values of C-reactive protein (CRP), lactate dehydrogenase (LDH), creatine phosphokinase (CPK), the number of excised lymph nodes, the use of postoperative analgesics and the length of hospital stay.
RESULTS: We collected data from 21 open and 17 laparoscopic right colectomies through a 5-year period. Measurements on the second postoperative day revealed mean CRP and CPK values significantly lower in the laparoscopic group compared to the open group, while LDH levels did not affirm major differences between the two groups. The mean number of lymph nodes excised during the open procedure was superior to those harvested in the laparoscopic group. The use of analgesics throughout the entire hospital stay was a combination of pethidine and tramadol for the first three postoperative days in open procedures, while paracetamol and, occasionally, tramadol were administered upon patient request following laparoscopic procedures. The mean hospital stay was substantially shorter in the laparoscopic group compared to the open surgery group.
CONCLUSION: Laparoscopic right colectomy is superior compared to open right colectomy with regards to postoperative analgesia and length of hospital stay, but also in certain postoperative laboratory values. Despite these there was no supremacy considering oncologic clearance.
Copyright © 2022, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.

Entities:  

Keywords:  Laparoscopic right colectomy; lymph node excision; postoperative values; right colon cancer

Mesh:

Year:  2022        PMID: 35241557      PMCID: PMC8931871          DOI: 10.21873/invivo.12788

Source DB:  PubMed          Journal:  In Vivo        ISSN: 0258-851X            Impact factor:   2.155


  17 in total

1.  Is laparoscopic colorectal cancer surgery equal to open surgery? An evidence based perspective.

Authors:  Beat M Künzli; Helmut Friess; Shailesh V Shrikhande
Journal:  World J Gastrointest Surg       Date:  2010-04-27

2.  Minimally invasive colon resection (laparoscopic colectomy).

Authors:  M Jacobs; J C Verdeja; H S Goldstein
Journal:  Surg Laparosc Endosc       Date:  1991-09

3.  Port-Site Recurrence of Cancer Associated With Laparoscopic Diagnosis and Resection: The European Experience.

Authors: 
Journal:  Semin Laparosc Surg       Date:  1995-09

4.  Cancer statistics, 2012.

Authors:  Rebecca Siegel; Deepa Naishadham; Ahmedin Jemal
Journal:  CA Cancer J Clin       Date:  2012-01-04       Impact factor: 508.702

5.  Tissue injuries after single-port and multiport laparoscopic gynecologic surgeries: A prospective multicenter study.

Authors:  Kyeong A So; Jae Kwan Lee; Jae Yun Song; Jae Won Kim; Nak Woo Lee; Kyung-Do Ki; Jong-Min Lee; Yong Jung Song; Yong Jin Na; Chun Hoe Ku; Jin Woo Shin; Chul Jung Kim; Un Suk Jung
Journal:  Exp Ther Med       Date:  2016-08-22       Impact factor: 2.447

Review 6.  Open compared with laparoscopic complete mesocolic excision with central lymphadenectomy for colon cancer: a systematic review and meta-analysis.

Authors:  C D Athanasiou; G A Markides; A Kotb; X Jia; S Gonsalves; D Miskovic
Journal:  Colorectal Dis       Date:  2016-07       Impact factor: 3.788

7.  Lymph node counts and survival rates after resection for colon and rectal cancer.

Authors:  Sandra L Wong
Journal:  Gastrointest Cancer Res       Date:  2009-03

8.  Lymph node retrieval in colorectal cancer: determining factors and prognostic significance.

Authors:  Johannes Betge; Lars Harbaum; Marion J Pollheimer; Richard A Lindtner; Peter Kornprat; Matthias P Ebert; Cord Langner
Journal:  Int J Colorectal Dis       Date:  2017-02-16       Impact factor: 2.571

9.  Clinical prediction score for superficial surgical site infection after appendectomy in adults with complicated appendicitis.

Authors:  Pinit Noorit; Boonying Siribumrungwong; Ammarin Thakkinstian
Journal:  World J Emerg Surg       Date:  2018-06-18       Impact factor: 5.469

10.  Comparison of short-term outcomes between laparoscopically-assisted vs. transverse-incision open right hemicolectomy for right-sided colon cancer: a retrospective study.

Authors:  Varut Lohsiriwat; Darin Lohsiriwat; Vitoon Chinswangwatanakul; Thawatchai Akaraviputh; Narong Lert-Akyamanee
Journal:  World J Surg Oncol       Date:  2007-05-11       Impact factor: 2.754

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