Literature DB >> 3523864

A new technique for drug susceptibility tests for Plasmodium falciparum by ethidium bromide fluoroassay.

S Waki, J Tamura, M Jingu, M Adachi, M Suzuki.   

Abstract

When Plasmodium falciparum parasites were stained with the fluorescent dye ethidium bromide, the fluorescence intensity of the solubilized parasites was correlated with the amount of nucleic acid present. It was possible to monitor development of the parasites from ring form to schizont by the fluoroassay. The assay system was applied to in vitro drug susceptibility tests on malaria parasites.

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Year:  1986        PMID: 3523864     DOI: 10.1016/0035-9203(86)90192-6

Source DB:  PubMed          Journal:  Trans R Soc Trop Med Hyg        ISSN: 0035-9203            Impact factor:   2.184


  6 in total

1.  Use of radioactive ethanolamine incorporation into phospholipids to assess in vitro antimalarial activity by the semiautomated microdilution technique.

Authors:  N Elabbadi; M L Ancelin; H J Vial
Journal:  Antimicrob Agents Chemother       Date:  1992-01       Impact factor: 5.191

2.  Assessment of the in vitro growth of Plasmodium falciparum using fluorometry.

Authors:  J Tamura; S Waki
Journal:  Z Parasitenkd       Date:  1986

3.  A fluorometric sensitivity test for chloroquine in Plasmodium falciparum isolates from patients.

Authors:  S Waki; J Tamura; T Takagi; M Adachi; M Suzuki
Journal:  Parasitol Res       Date:  1987       Impact factor: 2.289

Review 4.  Treatment of malaria--1990.

Authors:  D M Panisko; J S Keystone
Journal:  Drugs       Date:  1990-02       Impact factor: 9.546

5.  Simple, fast, and accurate fluorometric method to determine drug susceptibility of Plasmodium falciparum in 24-well suspension cultures.

Authors:  L J Smeijsters; N M Zijlstra; F F Franssen; J P Overdulve
Journal:  Antimicrob Agents Chemother       Date:  1996-04       Impact factor: 5.191

Review 6.  Development in Assay Methods for in Vitro Antimalarial Drug Efficacy Testing: A Systematic Review.

Authors:  Shweta Sinha; Phulen Sarma; Rakesh Sehgal; Bikash Medhi
Journal:  Front Pharmacol       Date:  2017-10-23       Impact factor: 5.810

  6 in total

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