Literature DB >> 35218215

Longitudinal Recovery of Speech Motor Function Following Facial Transplantation: A Prospective Observational Study.

Bridget J Perry1,2, Marziye Eshghi1,3, Kaila L Stipancic1,4, Brian Richburg1, Hayden Ventresca1, Bohdan Pomahac2, Jordan R Green1.   

Abstract

OBJECTIVES: Although facial transplantation is considered effective for restoring facial appearance, research on speech outcomes following surgery is limited. More research is critically needed to inform patients of expected rates and extent of recovery, and to develop interventions aimed at improving speech outcomes.
METHODS: Four patients in early recovery (3 weeks-24 months postsurgery) and three patients in late recovery (36-60 months postsurgery) were included. Clinical measures of speech recovery, including speech intelligibility measured using the Sentence Intelligibility Test, a lip strength testing device (Iowa Oral Performance Instrument), and kinematic measures of lip and jaw function measured using high-resolution 3D optical motion capture were used to describe the rate and extent of functional speech and lip recovery, describe and compare the rate of functional speech recovery and kinematic lip and jaw changes in early and late stages of recovery, and explore the association between kinematic measures and functional speech.
RESULTS: Speech intelligibility, speaking rate, and lip strength were below normative values in the first 2 years of postsurgery. Participants in the first 2 years of recovery demonstrated steeper slopes of improvement in clinical and kinematic measures than participants in the later stages of recovery (36-64 months). Gains in jaw range of movement and gains in lip speed and range of movement were significantly correlated with rates of sentence intelligibility improvement. Gains in lip strength were not associated with functional speech improvement.
CONCLUSIONS: These findings motivate ongoing work aimed at developing interventions for improving motor speech function in this population. LEVEL OF EVIDENCE: Step 3 Laryngoscope, 2022.
© 2022 The Authors. The Laryngoscope published by Wiley Periodicals LLC on behalf of The American Laryngological, Rhinological and Otological Society, Inc.

Entities:  

Keywords:  facial transplantation; motor speech; speech kinematics; speech movement; speech recovery

Year:  2022        PMID: 35218215      PMCID: PMC9402794          DOI: 10.1002/lary.30068

Source DB:  PubMed          Journal:  Laryngoscope        ISSN: 0023-852X            Impact factor:   2.970


  27 in total

1.  Induced fatigue effects on velopharyngeal closure force.

Authors:  D P Kuehn; J B Moon
Journal:  J Speech Lang Hear Res       Date:  2000-04       Impact factor: 2.297

2.  Age-related changes in orofacial force generation in women.

Authors:  M A McHenry; J T Minton; L L Hartley; K Calhoun; S S Barlow
Journal:  Laryngoscope       Date:  1999-05       Impact factor: 3.325

3.  Toward phonetic intelligibility testing in dysarthria.

Authors:  R D Kent; G Weismer; J F Kent; J C Rosenbek
Journal:  J Speech Hear Disord       Date:  1989-11

4.  Speech characteristics one year after first Belgian facial transplantation.

Authors:  Kristiane M Van Lierde; Nathalie Roche; Miet De Letter; Paul Corthals; Filip Stillaert; Hubert Vermeersch; Philippe Blondeel
Journal:  Laryngoscope       Date:  2014-02-10       Impact factor: 3.325

Review 5.  Maximum performance tests of speech production.

Authors:  R D Kent; J F Kent; J C Rosenbek
Journal:  J Speech Hear Disord       Date:  1987-11

6.  Lingual Pressure as a Clinical Indicator of Swallowing Function in Parkinson's Disease.

Authors:  Laura L Pitts; Sarah Morales; Julie A G Stierwalt
Journal:  J Speech Lang Hear Res       Date:  2018-02-15       Impact factor: 2.297

7.  Speech Movement Measures as Markers of Bulbar Disease in Amyotrophic Lateral Sclerosis.

Authors:  Sanjana Shellikeri; Jordan R Green; Madhura Kulkarni; Panying Rong; Rosemary Martino; Lorne Zinman; Yana Yunusova
Journal:  J Speech Lang Hear Res       Date:  2016-10-01       Impact factor: 2.297

8.  Articulatory movements during vowels in speakers with dysarthria and healthy controls.

Authors:  Yana Yunusova; Gary Weismer; John R Westbury; Mary J Lindstrom
Journal:  J Speech Lang Hear Res       Date:  2008-06       Impact factor: 2.297

9.  Maximal strength and endurance scores of the tongue, lip, and cheek in healthy, normal Koreans.

Authors:  Dong-Min Jeong; Yoo-Jin Shin; Na-Ra Lee; Ho-Kyung Lim; Han-Wool Choung; Kang-Mi Pang; Bong-Ju Kim; Soung-Min Kim; Jong-Ho Lee
Journal:  J Korean Assoc Oral Maxillofac Surg       Date:  2017-08-24

10.  Neuromotor Speech Recovery Across Different Behavioral Speech Modifications in Individuals Following Facial Transplantation.

Authors:  Marziye Eshghi; Bridget J Perry; Brian Richburg; Hayden M Ventresca; Bohdan Pomahac; Jordan R Green
Journal:  Front Neurol       Date:  2021-01-06       Impact factor: 4.003

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