Literature DB >> 35195752

Effect of coordinator-based osteoporosis intervention on quality of life in patients with fragility fractures: a prospective randomized trial.

R Okuda1, M Osaki2, Y Saeki3, T Okano4, K Tsuda5, T Nakamura6, Y Morio7, H Nagashima8, H Hagino9,2.   

Abstract

We examined the effects of the coordinator-based intervention on quality of life (QOL) in the aftermath of a fragility fracture, as well as factors predictive of post-fracture QOL. The coordinator-based interventions mitigated the decrease in QOL. Secondary fracture after primary fracture, however, was a significant predictor of lower QOL.
PURPOSE: This study aimed to determine the effects of the coordinator-based intervention on QOL in the aftermath of a fragility fracture, as well as factors predictive of post-fracture QOL, in an Asian population.
METHODS: Patients with new fractures in the intervention group received the coordinator-based intervention by a designated nurse certified as a coordinator, within 3 months of injury. QOL was evaluated using the Japanese version of the EuroQol 5 Dimension 5 Level (EQ-5D-5L) scale  before the fracture (through patient recollections) and at 0.5, 1, and 2 years after the primary fracture.
RESULTS: Data for 141 patients were analyzed: 70 in the liaison intervention (LI) group and 71 in the non-LI group. Significant intervention effects on QOL were observed at 6 months after the fracture; the QOL score was 0.079 points higher in the LI group than in the non-LI group (p=0.019). Further, the LI group reported significantly less pain/discomfort at 2 years after the fracture, compared to the non-LI group (p=0.037). In addition, secondary fractures were found to significantly prevent improvement and maintenance of QOL during the recovery period (p=0.015).
CONCLUSION: Short-term intervention effects were observable 6 months after the primary fracture, with the LI group mitigated the decrease in QOL. Few patients in the LI group reported pain/discomfort 2 years after the fracture, but there is uncertainty regarding its clinical significance. Secondary fracture after initial injury was a significant predictor of lower QOL after a fracture.
© 2022. International Osteoporosis Foundation and National Osteoporosis Foundation.

Entities:  

Keywords:  Coordinator-based program; EQ-5D-5L; Fracture liaison service; Osteoporosis; Secondary fracture prevention

Mesh:

Year:  2022        PMID: 35195752     DOI: 10.1007/s00198-021-06279-6

Source DB:  PubMed          Journal:  Osteoporos Int        ISSN: 0937-941X            Impact factor:   4.507


  29 in total

1.  The risk of a second hip fracture in patients after their first hip fracture.

Authors:  Hiroshi Hagino; Takeshi Sawaguchi; Naoto Endo; Yasuyo Ito; Tetsuo Nakano; Yoshinobu Watanabe
Journal:  Calcif Tissue Int       Date:  2011-11-12       Impact factor: 4.333

2.  Fracture liaison services for the evaluation and management of patients with osteoporotic fracture: a cost-effectiveness evaluation based on data collected over 8 years of service provision.

Authors:  A R McLellan; S E Wolowacz; E A Zimovetz; S M Beard; S Lock; L McCrink; F Adekunle; D Roberts
Journal:  Osteoporos Int       Date:  2011-05-24       Impact factor: 4.507

3.  Patients with prior fractures have an increased risk of future fractures: a summary of the literature and statistical synthesis.

Authors:  C M Klotzbuecher; P D Ross; P B Landsman; T A Abbott; M Berger
Journal:  J Bone Miner Res       Date:  2000-04       Impact factor: 6.741

4.  Fracture Liaison Services: the UK experience.

Authors:  P J Mitchell
Journal:  Osteoporos Int       Date:  2011-08-17       Impact factor: 4.507

5.  Incident Fragility Fractures Have a Long-Term Negative Impact on Health-Related Quality of Life of Older People: The Canadian Multicentre Osteoporosis Study.

Authors:  Sayem Borhan; Alexandra Papaioannou; Olga Gajic-Veljanoski; Courtney Kennedy; George Ioannidis; Claudie Berger; David Goltzman; Robert Josse; Christopher S Kovacs; David A Hanley; Jerilynn C Prior; Suzanne N Morin; Stephanie M Kaiser; Angela M Cheung; Lehana Thabane; Jonathan Adachi
Journal:  J Bone Miner Res       Date:  2019-02-05       Impact factor: 6.741

6.  Impact of prevalent fractures on quality of life: baseline results from the global longitudinal study of osteoporosis in women.

Authors:  Jonathan D Adachi; Silvano Adami; Stephen Gehlbach; Frederick A Anderson; Steven Boonen; Roland D Chapurlat; Juliet E Compston; Cyrus Cooper; Pierre Delmas; Adolfo Díez-Pérez; Susan L Greenspan; Frederick H Hooven; Andrea Z LaCroix; Robert Lindsay; J Coen Netelenbos; Olivia Wu; Johannes Pfeilschifter; Christian Roux; Kenneth G Saag; Philip N Sambrook; Stuart Silverman; Ethel S Siris; Grigor Nika; Nelson B Watts
Journal:  Mayo Clin Proc       Date:  2010-07-15       Impact factor: 7.616

7.  A fracture prevention service reduces further fractures two years after incident minimal trauma fracture.

Authors:  John Van der Kallen; Michelle Giles; Kerry Cooper; Kerry Gill; Vicki Parker; Agness Tembo; Gabor Major; Linda Ross; Jan Carter
Journal:  Int J Rheum Dis       Date:  2013-05-28       Impact factor: 2.454

8.  Prevalent vertebral deformity independently increases incident vertebral fracture risk in middle-aged and elderly Japanese women: the Japanese Population-based Osteoporosis (JPOS) Cohort Study.

Authors:  E Kadowaki; J Tamaki; M Iki; Y Sato; Y Chiba; E Kajita; S Kagamimori; Y Kagawa; H Yoneshima
Journal:  Osteoporos Int       Date:  2009-11-19       Impact factor: 4.507

9.  Recent trends in the incidence and lifetime risk of hip fracture in Tottori, Japan.

Authors:  H Hagino; K Furukawa; S Fujiwara; T Okano; H Katagiri; K Yamamoto; R Teshima
Journal:  Osteoporos Int       Date:  2008-07-17       Impact factor: 4.507

10.  An updated hip fracture projection in Asia: The Asian Federation of Osteoporosis Societies study.

Authors:  Ching-Lung Cheung; Seng Bin Ang; Manoj Chadha; Eddie Siu-Lun Chow; Yoon-Sok Chung; Fen Lee Hew; Unnop Jaisamrarn; Hou Ng; Yasuhiro Takeuchi; Chih-Hsing Wu; Weibo Xia; Julie Yu; Saeko Fujiwara
Journal:  Osteoporos Sarcopenia       Date:  2018-03-22
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