Literature DB >> 21607809

Fracture liaison services for the evaluation and management of patients with osteoporotic fracture: a cost-effectiveness evaluation based on data collected over 8 years of service provision.

A R McLellan1, S E Wolowacz, E A Zimovetz, S M Beard, S Lock, L McCrink, F Adekunle, D Roberts.   

Abstract

SUMMARY: The cost-effectiveness of Fracture Liaison Services (FLSs) for prevention of secondary fracture in osteoporosis patients in the United Kingdom (UK), and the cost associated with their widespread adoption, were evaluated. An estimated 18 fractures were prevented and £21,000 saved per 1,000 patients. Setup across the UK would cost an estimated £9.7 million.
INTRODUCTION: Only 11% to 28% of patients with a fragility fracture receive osteoporosis treatment in the UK. FLSs provide an efficient means to identify patients and are endorsed by the Department of Health but have not been widely adopted. The objective of this study was to evaluate the cost-effectiveness of FLSs in the UK and the cost associated with their widespread adoption.
METHODS: A cost-effectiveness and budget-impact model was developed, utilising detailed audit data collected by the West Glasgow FLS.
RESULTS: For a hypothetical cohort of 1,000 fragility-fracture patients (740 requiring treatment), 686 received treatment in the FLS compared with 193 in usual care. Assessments and osteoporosis treatments cost an additional £83,598 and £206,544, respectively, in the FLS; 18 fractures (including 11 hip fractures) were prevented, giving an overall saving of £21,000. Setup costs for widespread adoption of FLSs across the UK were estimated at £9.7 million.
CONCLUSIONS: FLSs are cost-effective for the prevention of further fractures in fragility-fracture patients. The cost of widespread adoption of FLS across the UK is small in comparison with other service provision and would be expected to result in important benefits in fractures avoided and reduced hospital bed occupancy.

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Year:  2011        PMID: 21607809     DOI: 10.1007/s00198-011-1534-0

Source DB:  PubMed          Journal:  Osteoporos Int        ISSN: 0937-941X            Impact factor:   4.507


  11 in total

Review 1.  Treatment of established osteoporosis: a systematic review and cost-utility analysis.

Authors:  J A Kanis; J E Brazier; M Stevenson; N W Calvert; M Lloyd Jones
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2.  The results of direct and indirect treatment comparisons in meta-analysis of randomized controlled trials.

Authors:  H C Bucher; G H Guyatt; L E Griffith; S D Walter
Journal:  J Clin Epidemiol       Date:  1997-06       Impact factor: 6.437

Review 3.  A systematic review and economic evaluation of alendronate, etidronate, risedronate, raloxifene and teriparatide for the prevention and treatment of postmenopausal osteoporosis.

Authors:  M Stevenson; M Lloyd Jones; E De Nigris; N Brewer; S Davis; J Oakley
Journal:  Health Technol Assess       Date:  2005-06       Impact factor: 4.014

4.  Persistence, reproducibility, and cost-effectiveness of an intervention to improve the quality of osteoporosis care after a fracture of the wrist: results of a controlled trial.

Authors:  S R Majumdar; J A Johnson; D A Lier; A S Russell; D A Hanley; S Blitz; I P Steiner; W P Maksymowych; D W Morrish; B R Holroyd; B H Rowe
Journal:  Osteoporos Int       Date:  2006-11-04       Impact factor: 4.507

5.  Refractures in patients at least forty-five years old. a prospective analysis of twenty-two thousand and sixty patients.

Authors:  C M Robinson; M Royds; A Abraham; M M McQueen; C M Court-Brown; J Christie
Journal:  J Bone Joint Surg Am       Date:  2002-09       Impact factor: 5.284

Review 6.  An updated systematic review of Health State Utility Values for osteoporosis related conditions.

Authors:  T Peasgood; K Herrmann; J A Kanis; J E Brazier
Journal:  Osteoporos Int       Date:  2009-03-07       Impact factor: 4.507

7.  A fracture liaison service for patients with osteoporotic fractures.

Authors:  Mayrine Fraser; Alastair R McLellan
Journal:  Prof Nurse       Date:  2004-01

8.  Osteoporosis case manager for patients with hip fractures: results of a cost-effectiveness analysis conducted alongside a randomized trial.

Authors:  Sumit R Majumdar; Douglas A Lier; Lauren A Beaupre; David A Hanley; Walter P Maksymowych; Angela G Juby; Neil R Bell; Donald W Morrish
Journal:  Arch Intern Med       Date:  2009-01-12

9.  The fracture liaison service: success of a program for the evaluation and management of patients with osteoporotic fracture.

Authors:  Alastair R McLellan; Stephen J Gallacher; Mayrine Fraser; Carol McQuillian
Journal:  Osteoporos Int       Date:  2003-11-05       Impact factor: 4.507

10.  A coordinator program in post-fracture osteoporosis management improves outcomes and saves costs.

Authors:  Beate Sander; Victoria Elliot-Gibson; Dorcas E Beaton; Earl R Bogoch; Andreas Maetzel
Journal:  J Bone Joint Surg Am       Date:  2008-06       Impact factor: 5.284

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  86 in total

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Authors:  T P Olenginski; G Maloney-Saxon; C K Matzko; K Mackiewicz; H L Kirchner; A Bengier; E D Newman
Journal:  Osteoporos Int       Date:  2014-11-15       Impact factor: 4.507

2.  Cost-effectiveness of the Concord Minimal Trauma Fracture Liaison service, a prospective, controlled fracture prevention study.

Authors:  M S Cooper; A J Palmer; M J Seibel
Journal:  Osteoporos Int       Date:  2011-09-28       Impact factor: 4.507

3.  Secondary fracture prevention.

Authors:  Robert A Adler
Journal:  Curr Osteoporos Rep       Date:  2012-03       Impact factor: 5.096

4.  Hip fracture and other predictors of anti-osteoporosis drug use in Norway.

Authors:  H M Devold; A J Søgaard; A Tverdal; J A Falch; K Furu; H E Meyer
Journal:  Osteoporos Int       Date:  2012-07-10       Impact factor: 4.507

5.  The Fracture Liaison Service to close the osteoporosis care gap: a leadership educational model for undergraduate and postgraduate trainees.

Authors:  Micah Yu; Christina Downey; Karina D Torralba
Journal:  Clin Rheumatol       Date:  2019-11-23       Impact factor: 2.980

Review 6.  Fracture Liaison Services in the United Kingdom.

Authors:  Paul J Mitchell
Journal:  Curr Osteoporos Rep       Date:  2013-12       Impact factor: 5.096

7.  Cost-effectiveness of a fracture liaison service--a real-world evaluation after 6 years of service provision.

Authors:  J H E Yong; L Masucci; J S Hoch; R Sujic; D Beaton
Journal:  Osteoporos Int       Date:  2015-08-15       Impact factor: 4.507

8.  Economic evaluation of osteoporosis liaison service for secondary fracture prevention in postmenopausal osteoporosis patients with previous hip fracture in Japan.

Authors:  K Moriwaki; S Noto
Journal:  Osteoporos Int       Date:  2016-10-04       Impact factor: 4.507

9.  Delivering a quality-assured fracture liaison service in a UK teaching hospital-is it achievable?

Authors:  K E Shipman; J Stammers; A Doyle; N Gittoes
Journal:  Osteoporos Int       Date:  2016-05-18       Impact factor: 4.507

10.  Multimodal intervention to improve osteoporosis care in home health settings: results from a cluster randomized trial.

Authors:  M L Kilgore; R Outman; J L Locher; J J Allison; A Mudano; B Kitchin; K G Saag; J R Curtis
Journal:  Osteoporos Int       Date:  2013-03-28       Impact factor: 4.507

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