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Literature DB >> 35191916

Haloperoxidase-mimicking CeO_2-x nanorods for the deactivation of human coronavirus OC43.

Jiayan Lang¹, Xiaojing Ma¹, Pengyu Chen¹, Max D Serota¹, Nicole M Andre², Gary R Whittaker², Rong Yang¹.

Abstract

Despite the excellent antibacterial and antifouling effects of haloperoxidase (HPO)-mimicking CeO2-x nanorods, their antiviral efficiency has not been explored. Herein, we designed and synthesized CeO2-x nanorods with varying aspect ratios via the hydrothermal method. CeO2-x nanorods catalysed the oxidative bromination of Br- and H2O2 to HOBr, the kinetics of which were studied systematically using a phenol red assay. The CeO2-x nanorods with the optimized aspect ratio (i.e., 4.5) demonstrated strong antiviral efficacies against the human coronavirus OC43, with no visible toxicity to the HCT-8 host cells.

Entities: Chemical

Mesh：

Substances：
Cerium
Hydrogen Peroxide

Year: 2022 PMID： 35191916 PMCID： PMC8941489 DOI： 10.1039/d1nr06966g

Source DB: PubMed Journal: Nanoscale ISSN： 2040-3364 Impact factor: 7.790

31 in total

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3. Peroxidase-mediated virucidal systems.

Authors: M E Belding; S J Klebanoff; C G Ray
Journal: Science Date: 1970-01-09 Impact factor: 47.728

4. Nanocomposite antimicrobials prevent bacterial growth through the enzyme-like activity of Bi-doped cerium dioxide (Ce_1-xBi_xO_2-δ).

Authors: Hajo Frerichs; Eva Pütz; Felix Pfitzner; Tobias Reich; Athanasios Gazanis; Martin Panthöfer; Jens Hartmann; Olga Jegel; Ralf Heermann; Wolfgang Tremel
Journal: Nanoscale Date: 2020-10-29 Impact factor: 7.790

5. Multifunctional Graphdiyne-Cerium Oxide Nanozymes Facilitate MicroRNA Delivery and Attenuate Tumor Hypoxia for Highly Efficient Radiotherapy of Esophageal Cancer.

Authors: Xuantong Zhou; Min You; Fuhui Wang; Zhenzhen Wang; Xingfa Gao; Chao Jing; Jiaming Liu; Mengyu Guo; Jiayang Li; Aiping Luo; Huibiao Liu; Zhihua Liu; Chunying Chen
Journal: Adv Mater Date: 2021-05-05 Impact factor: 30.849

Haloperoxidase-mimicking CeO_2-x nanorods for the deactivation of human coronavirus OC43.

1. Auto-catalytic ceria nanoparticles offer neuroprotection to adult rat spinal cord neurons.

2. Hypochlorous Acid: an ideal wound care agent with powerful microbicidal, antibiofilm, and wound healing potency.

3. Peroxidase-mediated virucidal systems.

4. Nanocomposite antimicrobials prevent bacterial growth through the enzyme-like activity of Bi-doped cerium dioxide (Ce_1-xBi_xO_2-δ).

5. Multifunctional Graphdiyne-Cerium Oxide Nanozymes Facilitate MicroRNA Delivery and Attenuate Tumor Hypoxia for Highly Efficient Radiotherapy of Esophageal Cancer.

6. Hypochlorous-Acid-Generating Electrochemical Scaffold for Treatment of Wound Biofilms.

Review 7. Infectious Disease Threats in the Twenty-First Century: Strengthening the Global Response.

Review 8. Emerging Pandemic Diseases: How We Got to COVID-19.

Review 1. Insights on catalytic mechanism of CeO₂ as multiple nanozymes.

Haloperoxidase-mimicking CeO2-x nanorods for the deactivation of human coronavirus OC43.

1. Auto-catalytic ceria nanoparticles offer neuroprotection to adult rat spinal cord neurons.

2. Hypochlorous Acid: an ideal wound care agent with powerful microbicidal, antibiofilm, and wound healing potency.

3. Peroxidase-mediated virucidal systems.

4. Nanocomposite antimicrobials prevent bacterial growth through the enzyme-like activity of Bi-doped cerium dioxide (Ce1-xBixO2-δ).

5. Multifunctional Graphdiyne-Cerium Oxide Nanozymes Facilitate MicroRNA Delivery and Attenuate Tumor Hypoxia for Highly Efficient Radiotherapy of Esophageal Cancer.

6. Hypochlorous-Acid-Generating Electrochemical Scaffold for Treatment of Wound Biofilms.

Review 7. Infectious Disease Threats in the Twenty-First Century: Strengthening the Global Response.

Review 8. Emerging Pandemic Diseases: How We Got to COVID-19.

Review 1. Insights on catalytic mechanism of CeO2 as multiple nanozymes.

Haloperoxidase-mimicking CeO_2-x nanorods for the deactivation of human coronavirus OC43.

4. Nanocomposite antimicrobials prevent bacterial growth through the enzyme-like activity of Bi-doped cerium dioxide (Ce_1-xBi_xO_2-δ).

Review 1. Insights on catalytic mechanism of CeO₂ as multiple nanozymes.