Literature DB >> 17222903

Auto-catalytic ceria nanoparticles offer neuroprotection to adult rat spinal cord neurons.

Mainak Das1, Swanand Patil, Neelima Bhargava, Jung-Fong Kang, Lisa M Riedel, Sudipta Seal, James J Hickman.   

Abstract

This paper describes the evaluation of the auto-catalytic anti-oxidant behavior and biocompatibility of cerium oxide nanoparticles for applications in spinal cord repair and other diseases of the central nervous system. The application of a single dose of nano-ceria at a nano-molar concentration is biocompatible, regenerative and provides a significant neuroprotective effect on adult rat spinal cord neurons. Retention of neuronal function is demonstrated from electrophysiological recordings and the possibility of its application to prevent ischemic insult is suggested from an oxidative injury assay. A mechanism is proposed to explain the auto-catalytic properties of these nanoparticles.

Entities:  

Mesh：

Substances：

Year:  2007        PMID： 17222903      PMCID： PMC1913191          DOI： 10.1016/j.biomaterials.2006.11.036

Source DB:  PubMed          Journal:  Biomaterials        ISSN： 0142-9612            Impact factor:   12.479


  21 in total

1.  Antioxidants are required during the early critical period, but not later, for neuronal survival.

Authors:  Seth W Perry; John P Norman; Angela Litzburg; Harris A Gelbard
Journal:  J Neurosci Res       Date:  2004-11-15       Impact factor: 4.164

2.  A defined system to allow skeletal muscle differentiation and subsequent integration with silicon microstructures.

Authors:  Mainak Das; Cassie A Gregory; Peter Molnar; Lisa M Riedel; Kerry Wilson; James J Hickman
Journal:  Biomaterials       Date:  2006-05-02       Impact factor: 12.479

3.  Controlled outgrowth of dissociated neurons on patterned substrates.

Authors:  D Kleinfeld; K H Kahler; P E Hockberger
Journal:  J Neurosci       Date:  1988-11       Impact factor: 6.167

4.  Electrophysiological and morphological characterization of rat embryonic motoneurons in a defined system.

Authors:  Mainak Das; Peter Molnar; Halagowder Devaraj; Matthew Poeta; James J Hickman
Journal:  Biotechnol Prog       Date:  2003 Nov-Dec

5.  Hydroxyl radicals generated in the rat spinal cord at the level produced by impact injury induce cell death by necrosis and apoptosis: protection by a metalloporphyrin.

Authors:  F Bao; D Liu
Journal:  Neuroscience       Date:  2004       Impact factor: 3.590

6.  Hydroxyl radicals generated in vivo kill neurons in the rat spinal cord: electrophysiological, histological, and neurochemical results.

Authors:  D Liu; R Yang; X Yan; D J McAdoo
Journal:  J Neurochem       Date:  1994-01       Impact factor: 5.372

7.  Optimized survival of hippocampal neurons in B27-supplemented Neurobasal, a new serum-free medium combination.

Authors:  G J Brewer; J R Torricelli; E K Evege; P J Price
Journal:  J Neurosci Res       Date:  1993-08-01       Impact factor: 4.164

8.  Surface determinants of neuronal survival and growth on self-assembled monolayers in culture.

Authors:  D A Stenger; C J Pike; J J Hickman; C W Cotman
Journal:  Brain Res       Date:  1993-12-10       Impact factor: 3.252

Review 9.  [Free radicals and neural cell damage].

Authors:  N Ogawa
Journal:  Rinsho Shinkeigaku       Date:  1994-12

10.  Localization of NADH oxidase on the surface of human polymorphonuclear leukocytes by a new cytochemical method.

Authors:  R T Briggs; D B Drath; M L Karnovsky; M J Karnovsky
Journal:  J Cell Biol       Date:  1975-12       Impact factor: 10.539
View more
  133 in total

1.  Protein adsorption and cellular uptake of cerium oxide nanoparticles as a function of zeta potential.

Authors:  Swanand Patil; Amanda Sandberg; Eric Heckert; William Self; Sudipta Seal
Journal:  Biomaterials       Date:  2007-08-01       Impact factor: 12.479

2.  Temporal neurotransmitter conditioning restores the functional activity of adult spinal cord neurons in long-term culture.

Authors:  Mainak Das; Neelima Bhargava; Abhijeet Bhalkikar; Jung Fong Kang; James J Hickman
Journal:  Exp Neurol       Date:  2007-09-26       Impact factor: 5.330

3.  Fenton-like reaction catalyzed by the rare earth inner transition metal cerium.

Authors:  Eric G Heckert; Sudipta Seal; William T Self
Journal:  Environ Sci Technol       Date:  2008-07-01       Impact factor: 9.028

4.  Beneficial effects of cerium oxide nanoparticles in development of chondrocyte-seeded hydrogel constructs and cellular response to interleukin insults.

Authors:  Sathish Ponnurangam; Grace D O'Connell; Irina V Chernyshova; Katherine Wood; Clark Tung-Hui Hung; Ponisseril Somasundaran
Journal:  Tissue Eng Part A       Date:  2014-06-25       Impact factor: 3.845

5.  A phosphate-dependent shift in redox state of cerium oxide nanoparticles and its effects on catalytic properties.

Authors:  Sanjay Singh; Talib Dosani; Ajay S Karakoti; Amit Kumar; Sudipta Seal; William T Self
Journal:  Biomaterials       Date:  2011-06-24       Impact factor: 12.479

6.  Glutamate oxidase biosensor based on mixed ceria and titania nanoparticles for the detection of glutamate in hypoxic environments.

Authors:  Rıfat Emrah Özel; Cristina Ispas; Mallikarjunarao Ganesana; J C Leiter; Silvana Andreescu
Journal:  Biosens Bioelectron       Date:  2013-09-11       Impact factor: 10.618

7.  Aliphatic hyperbranched polyester: a new building block in the construction of multifunctional nanoparticles and nanocomposites.

Authors:  Santimukul Santra; Charalambos Kaittanis; J Manuel Perez
Journal:  Langmuir       Date:  2010-04-20       Impact factor: 3.882

8.  Scavenging of reactive oxygen and nitrogen species with nanomaterials.

Authors:  Carolina A Ferreira; Dalong Ni; Zachary T Rosenkrans; Weibo Cai
Journal:  Nano Res       Date:  2018-05-26       Impact factor: 8.897

9.  Cerium oxide nanoparticles inhibit adipogenesis in rat mesenchymal stem cells: potential therapeutic implications.

Authors:  Antonella Rocca; Virgilio Mattoli; Barbara Mazzolai; Gianni Ciofani
Journal:  Pharm Res       Date:  2014-05-08       Impact factor: 4.200

10.  Role of Cerium Oxide Nanoparticles in a Paraquat-Induced Model of Oxidative Stress: Emergence of Neuroprotective Results in the Brain.

Authors:  Akram Ranjbar; Sara Soleimani Asl; Farzin Firozian; Hamid Heidary Dartoti; Saman Seyedabadi; Masoumeh Taheri Azandariani; Maziar Ganji
Journal:  J Mol Neurosci       Date:  2018-10-03       Impact factor: 3.444
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.