Literature DB >> 3518775

Protective effect of theophylline on histamine-induced bronchoconstriction in asthmatic children.

S Levene, S A McKenzie.   

Abstract

The bronchial responsiveness of a group of asthmatic children was studied using histamine stimulation after a single dose of theophylline and after placebo. Theophylline, when levels were greater than 10 micrograms ml-1 significantly reduced responsiveness but only by just over one doubling concentration of histamine (P less than 0.001).

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Year:  1986        PMID： 3518775      PMCID： PMC1400938          DOI： 10.1111/j.1365-2125.1986.tb05220.x

Source DB:  PubMed          Journal:  Br J Clin Pharmacol        ISSN： 0306-5251            Impact factor:   4.335


  16 in total

1.  Assessment of oral antiasthmatic drugs by inhalation challenges.

Authors:  C J Falliers
Journal:  J Allergy Clin Immunol       Date:  1979-12       Impact factor: 10.793

2.  A sustained release theophylline preparation: efficacy in childhood asthma with low serum theophylline levels.

Authors:  G S Rachelefsky; R M Katz; S C Siegel
Journal:  Ann Allergy       Date:  1978-04

3.  Controlled trial of slow-release aminophylline in childhood asthma: are short-term trials valid?

Authors:  N Wilson; M Silverman
Journal:  Br Med J (Clin Res Ed)       Date:  1982-03-20

4.  Reproducibility of histamine challenge tests in asthmatic children.

Authors:  D Hariparsad; N Wilson; C Dixon; M Silverman
Journal:  Thorax       Date:  1983-04       Impact factor: 9.139

5.  Comparison of peak expiratory flow rate and forced expiratory volume in one second in histamine challenge studies in children.

Authors:  R L Henry; C M Mellis; R T South; S J Simpson
Journal:  Br J Dis Chest       Date:  1982-04

6.  Airway responsiveness to histamine and methacholine: relationship to minimum treatment to control symptoms of asthma.

Authors:  E F Juniper; P A Frith; F E Hargreave
Journal:  Thorax       Date:  1981-08       Impact factor: 9.139

Review 7.  Bronchial responsiveness to histamine or methacholine in asthma: measurement and clinical significance.

Authors:  F E Hargreave; G Ryan; N C Thomson; P M O'Byrne; K Latimer; E F Juniper; J Dolovich
Journal:  J Allergy Clin Immunol       Date:  1981-11       Impact factor: 10.793

8.  Standardization of inhalation provocation tests: influence of nebulizer output, particle size, and method of inhalation.

Authors:  G Ryan; M B Dolovich; G Obminski; D W Cockcroft; E Juniper; F E Hargreave; M T Newhouse
Journal:  J Allergy Clin Immunol       Date:  1981-02       Impact factor: 10.793

9.  Slow-release oral salbutamol and aminophylline in nocturnal asthma: relation of overnight changes in lung function and plasma drug levels.

Authors:  A J Fairfax; W R McNabb; H J Davies; S G Spiro
Journal:  Thorax       Date:  1980-07       Impact factor: 9.139

10.  Acute and chronic theophylline therapy in exercise-induced bronchospasm.

Authors:  C W Bierman; G G Shapiro; W E Pierson; C S Dorsett
Journal:  Pediatrics       Date:  1977-12       Impact factor: 7.124
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  3 in total

1.  Current state of theophylline in asthma.

Authors:  S McKenzie
Journal:  Arch Dis Child       Date:  1986-11       Impact factor: 3.791

2.  Effect of theophylline and enprofylline on bronchial hyperresponsiveness.

Authors:  G H Koëter; J Kraan; M Boorsma; J H Jonkman; T W van der Mark
Journal:  Thorax       Date:  1989-12       Impact factor: 9.139

3.  Dose related effects of salbutamol and ipratropium bromide on airway calibre and reactivity in subjects with asthma.

Authors:  J Britton; S P Hanley; H V Garrett; J W Hadfield; A E Tattersfield
Journal:  Thorax       Date:  1988-04       Impact factor: 9.139
  3 in total

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