Literature DB >> 35178287

Optic Pit Maculopathy: Clinical Features and Management Options.

Prashanth G Iyer1, Harry W Flynn1, Kenneth C Fan1, Audina M Berrocal1, Raquel Goldhardt1.   

Abstract

PURPOSE OF REVIEW: In this article, we review the pathogenesis, clinical features, imaging modalities and latest management options for optic pit maculopathy (OPM). RECENT
FINDINGS: The pathogenesis of OPM remains to be unclear, but imaging tools such as optical coherence tomography (OCT) and OCT angiography are enhancing our knowledge. Observation continues to be the best management strategy for patients with good visual acuity, and many cases have demonstrated spontaneous resolution. For more advanced, progressive vision loss, treatment options involving vitrectomy can be considered and discussed with the patient. Supplementary techniques to vitrectomy have been reported in small studies with relative success such as glial tissue peeling, inverted internal limiting membrane flap, optic pit plugging, and retinal fenestration.
SUMMARY: While there are multiple treatment options available for OPM, there is no consensus on the technique and surgical timing. Individual patient factors and the risks-benefits of treatment must be taken into account in guiding management. Larger clinical trials will further assist in decision making for treating OPM.

Entities:  

Keywords:  Optic pit maculopathy; congenital optic pit; lamina cribosa; maculopathy; optic pit; pars plana vitrectomy

Year:  2021        PMID: 35178287      PMCID: PMC8845502          DOI: 10.1007/s40135-021-00274-0

Source DB:  PubMed          Journal:  Curr Ophthalmol Rep        ISSN: 2167-4868


  96 in total

Review 1.  The genetics and ocular findings of Alagille syndrome.

Authors:  Ben J Kim; Anne B Fulton
Journal:  Semin Ophthalmol       Date:  2007 Oct-Dec       Impact factor: 1.975

2.  Optical coherence tomography study of vitreoretinal interface in full thickness macular hole associated with optic disk pit maculopathy.

Authors:  P G Theodossiadis; V G Grigoropoulos; J Emfietzoglou; P Nikolaidis; G P Theodossiadis
Journal:  Eur J Ophthalmol       Date:  2007 Mar-Apr       Impact factor: 2.597

3.  Optic Disc Pit Maculopathy: A Two-Year Nationwide Prospective Population-based Study.

Authors:  David H W Steel; Javid Suleman; Declan C Murphy; Anna Song; Steve Dodds; Jon Rees
Journal:  Ophthalmology       Date:  2018-06-07       Impact factor: 12.079

4.  Clinicopathologic Correlation of the Optic Pit Glial Plug in Optic Disc Pit Maculopathy.

Authors:  Nicolas A Yannuzzi; Xiao Yi Zhou; Pedro Monsalve; Sander R Dubovy; William E Smiddy
Journal:  Ophthalmic Surg Lasers Imaging Retina       Date:  2018-12-01       Impact factor: 1.300

5.  Vitreoretinal surgery for optic pit associated serous macular detachment: a discussion of two cases.

Authors:  Sophie J Bakri; Paul M Beer
Journal:  Int Ophthalmol       Date:  2004-05       Impact factor: 2.031

6.  Optic disc pit maculopathy: the value of small-gauge vitrectomy, peeling, laser treatment, and gas tamponade.

Authors:  Stanislao Rizzo; Claudia Belting; Federica Genovesi-Ebert; Emanuele Di Bartolo; Federica Cresti; Laura Cinelli; Luca Allegrini
Journal:  Eur J Ophthalmol       Date:  2012 Jul-Aug       Impact factor: 2.597

7.  Communication between the subretinal space and the vitreous cavity in the morning glory syndrome.

Authors:  G E Coll; S Chang; T E Flynn; G C Brown
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  1995-07       Impact factor: 3.117

8.  Optic pit maculopathy after laser-assisted in situ keratomileusis.

Authors:  Hanna Rodriguez-Coleman; William M Schiff; John C Hwang; Mark G Speaker
Journal:  Can J Ophthalmol       Date:  2007-02       Impact factor: 1.882

9.  Long-term outcomes of pars plana vitrectomy without internal limiting membrane peeling for optic disc pit maculopathy.

Authors:  R Avci; S Yilmaz; U U Inan; B Kaderli; M Kurt; O Yalcinbayir; M Yildiz; A Yucel
Journal:  Eye (Lond)       Date:  2013-09-13       Impact factor: 3.775

10.  Oral acetazolamide as a medical adjuvant to retinal surgery in optic disc pit maculopathy in a pediatric patient.

Authors:  Carla J Osigian; Daniel Gologorsky; Kara M Cavuoto; Audina Berrocal; Victor Villegas
Journal:  Am J Ophthalmol Case Rep       Date:  2020-01-16
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