Xudong Yang1, Yali Wang2, Yongping Liu3, Lei Shang4, Zhijian Cheng5, Liping Fang6, Jian Zhang7, Yifan Feng7, Kuiwei Zhang7, Shanjiao Jiang8, Xijing He9. 1. Department of Neurorehabilitation, Xi'an International Medical Center Hospital Xi'an 710100, Shaanxi Province, China. 2. Department of Rehabilitation, Xi'an International Medical Center Hospital Xi'an 710100, Shaanxi Province, China. 3. Department of Trauma and Critical Medicine, Xi'an International Medical Center Hospital Xi'an 710100, Shaanxi Province, China. 4. Department of Traditional Chinese Medicine, Xi'an International Medical Center Hospital Xi'an 710100, Shaanxi Province, China. 5. Department of Orthopedics, Second Affiliated Hospital of Xi'an Jiaotong University Xi'an 710004, Shaanxi Province, China. 6. Respiratory Department, Xi'an People's Hospital Xi'an 710100, Shaanxi Province, China. 7. Xi'an International Medical Center Hospital Xi'an 710100, Shaanxi Province, China. 8. Science and Education Division, Xi'an International Medical Center Hospital Xi'an 710100, Shaanxi Province, China. 9. The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an International Medical Center Hospital Xi'an 710100, Shaanxi Province, China.
Abstract
OBJECTIVES: Traditional Chinese medicine has been reported to be effective in the treatment of epidemic diseases. Here, we aimed to investigate the effects of combined therapy of Chinese and western medicine on coronavirus disease 2019 (COVID-19). METHODS: A total of 60 patients diagnosed with COVID-19 were enrolled. Both the ordinary and severely affected patients were randomly divided into Groups A-C each with 10 cases each. The patients in Group A-C received Western medicine, Western medicine + traditional Chinese medicine, and Western medicine + traditional Chinese medicine + high dose of vitamin C, respectively. The time of disease recovery, symptoms disappearance, chest CT improvement, and tongue amelioration was recorded. Leukocyte, neutrophil and lymphocyte were monitored, as well as C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), procalitonin (PCT), inflammatory factors, partial pressure of oxygen and carbon dioxide (PaCO2) and oxygenation index (PaO2). Urinary tract stones, liver function, and other side-effects such as gastrointestinal dysfunction were also investigated. RESULTS: Traditional Chinese medicine enhanced the effect of Western medicine, including the reduction of CRP, ESR, PCT, and inflammatory factors, and the increase of leukocyte, neutrophil, and lymphocyte counts, and the improvement of respiratory rate, PaO2, PaCO2, and oxygenation index. Traditional Chinese medicine combined with high-dose Vitamin C therapy more effectively shortened the time of disease recovery, symptom disappearance, chest CT improvement, and tongue amelioration. CONCLUSIONS: a combined therapy of Western medicine, traditional Chinese medicine, and high dose of Vitamin C results in a most effective outcome in the treatment of COVID-19. AJTR
OBJECTIVES: Traditional Chinese medicine has been reported to be effective in the treatment of epidemic diseases. Here, we aimed to investigate the effects of combined therapy of Chinese and western medicine on coronavirus disease 2019 (COVID-19). METHODS: A total of 60 patients diagnosed with COVID-19 were enrolled. Both the ordinary and severely affected patients were randomly divided into Groups A-C each with 10 cases each. The patients in Group A-C received Western medicine, Western medicine + traditional Chinese medicine, and Western medicine + traditional Chinese medicine + high dose of vitamin C, respectively. The time of disease recovery, symptoms disappearance, chest CT improvement, and tongue amelioration was recorded. Leukocyte, neutrophil and lymphocyte were monitored, as well as C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), procalitonin (PCT), inflammatory factors, partial pressure of oxygen and carbon dioxide (PaCO2) and oxygenation index (PaO2). Urinary tract stones, liver function, and other side-effects such as gastrointestinal dysfunction were also investigated. RESULTS: Traditional Chinese medicine enhanced the effect of Western medicine, including the reduction of CRP, ESR, PCT, and inflammatory factors, and the increase of leukocyte, neutrophil, and lymphocyte counts, and the improvement of respiratory rate, PaO2, PaCO2, and oxygenation index. Traditional Chinese medicine combined with high-dose Vitamin C therapy more effectively shortened the time of disease recovery, symptom disappearance, chest CT improvement, and tongue amelioration. CONCLUSIONS: a combined therapy of Western medicine, traditional Chinese medicine, and high dose of Vitamin C results in a most effective outcome in the treatment of COVID-19. AJTR
Authors: Ali A Rabaan; Shamsah H Al-Ahmed; Shafiul Haque; Ranjit Sah; Ruchi Tiwari; Yashpal Singh Malik; Kuldeep Dhama; M Iqbal Yatoo; D Katterine Bonilla-Aldana; Alfonso J Rodriguez-Morales Journal: Infez Med Date: 2020 Ahead Of Print Jun 1
Authors: Ruben Manuel Luciano Colunga Biancatelli; Max Berrill; Paul E Marik Journal: Expert Rev Anti Infect Ther Date: 2019-12-23 Impact factor: 5.091
Authors: Tobias Sinnberg; Christa Lichtensteiger; Katharina Hill-Mündel; Christian Leischner; Heike Niessner; Christian Busch; Olga Renner; Nina Wyss; Lukas Flatz; Ulrich M Lauer; Ludwig E Hoelzle; Donatus Nohr; Markus Burkard; Luigi Marongiu; Sascha Venturelli Journal: Antioxidants (Basel) Date: 2022-08-15