Literature DB >> 35149397

Calpain-1 inhibition attenuates in vivo thrombosis in a humanized model of sickle cell disease.

Farha Mithila1, Christopher Schwake1, Chao Fang2, Glenn Merrill-Skoloff2, Lidija Covic3, Daniel I Fritz1, Toshihiko Hanada1, Robert Flaumenhaft2, Athar H Chishti4.   

Abstract

Entities:  

Keywords:  Calpain-1; Platelets; Sickle cell disease; Thrombosis

Mesh：

Substances：

Year:  2022        PMID： 35149397      PMCID： PMC9207783          DOI： 10.1016/j.thromres.2022.01.029

Source DB:  PubMed          Journal:  Thromb Res        ISSN： 0049-3848            Impact factor:   10.407


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  10 in total

1.  Calpain-1 knockout reveals broad effects on erythrocyte deformability and physiology.

Authors:  Adam Wieschhaus; Anwar Khan; Asma Zaidi; Henry Rogalin; Toshihiko Hanada; Fei Liu; Lucia De Franceschi; Carlo Brugnara; Alicia Rivera; Athar H Chishti
Journal:  Biochem J       Date:  2012-11-15       Impact factor: 3.857

2.  Disruption of the mouse mu-calpain gene reveals an essential role in platelet function.

Authors:  M Azam; S S Andrabi; K E Sahr; L Kamath; A Kuliopulos; A H Chishti
Journal:  Mol Cell Biol       Date:  2001-03       Impact factor: 4.272

3.  Genetic inactivation of calpain-1 attenuates pain sensitivity in a humanized mouse model of sickle cell disease.

Authors:  Jennifer O Nwankwo; Jianxun Lei; Jian Xu; Alicia Rivera; Kalpna Gupta; Athar H Chishti
Journal:  Haematologica       Date:  2016-07-14       Impact factor: 9.941

4.  Elevated erythrocyte calcium in sickle cell disease.

Authors:  J W Eaton; T D Skelton; H S Swofford; C E Kolpin; H S Jacob
Journal:  Nature       Date:  1973-11-09       Impact factor: 49.962

5.  Calpain regulation of cytoskeletal signaling complexes in von Willebrand factor-stimulated platelets. Distinct roles for glycoprotein Ib-V-IX and glycoprotein IIb-IIIa (integrin alphaIIbbeta3) in von Willebrand factor-induced signal transduction.

Authors:  Y Yuan; S M Dopheide; C Ivanidis; H H Salem; S P Jackson
Journal:  J Biol Chem       Date:  1997-08-29       Impact factor: 5.157

6.  Double knockouts reveal that protein tyrosine phosphatase 1B is a physiological target of calpain-1 in platelets.

Authors:  Shafi M Kuchay; Nayoung Kim; Elizabeth A Grunz; William P Fay; Athar H Chishti
Journal:  Mol Cell Biol       Date:  2007-06-18       Impact factor: 4.272

Review 7.  Calcium signaling in platelets.

Authors:  D Varga-Szabo; A Braun; B Nieswandt
Journal:  J Thromb Haemost       Date:  2009-04-24       Impact factor: 5.824

8.  Calpain-1 regulates platelet function in a humanized mouse model of sickle cell disease.

Authors:  Jennifer O Nwankwo; Thomas Gremmel; Anja J Gerrits; Farha J Mithila; Rod R Warburton; Nicholas S Hill; Yunzhe Lu; Lauren J Richey; Joseph A Jakubowski; Andrew L Frelinger; Athar H Chishti
Journal:  Thromb Res       Date:  2017-10-26       Impact factor: 3.944

9.  COVID-19 patient with coronary thrombosis supported with ECMO and Impella 5.0 ventricular assist device: a case report.

Authors:  Kamen Valchanov; Unni Krishnan; Stephen P Hoole; Will R Davies; Stephen Pettit; Nicola Jones; Jas Parmar; Pedro Catarino; Mohamed Osman; Marius Berman
Journal:  Eur Heart J Case Rep       Date:  2020-11-20

10.  COVID-19 in individuals with sickle cell disease/trait compared with other Black individuals.

Authors:  Ashima Singh; Amanda M Brandow; Julie A Panepinto
Journal:  Blood Adv       Date:  2021-04-13
  10 in total

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