Literature DB >> 27418647

Genetic inactivation of calpain-1 attenuates pain sensitivity in a humanized mouse model of sickle cell disease.

Jennifer O Nwankwo1, Jianxun Lei2, Jian Xu3, Alicia Rivera4, Kalpna Gupta2, Athar H Chishti5.   

Abstract

Entities:  

Keywords:  calpain-1; genetic inactivation; humanized mouse model; pain; sickle cell disease

Mesh：

Substances：

Year:  2016        PMID： 27418647      PMCID： PMC5046659          DOI： 10.3324/haematol.2016.148106

Source DB:  PubMed          Journal:  Haematologica        ISSN： 0390-6078            Impact factor:   9.941


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  16 in total

1.  Spinal glial activation and oxidative stress are alleviated by treatment with curcumin or coenzyme Q in sickle mice.

Authors:  Yessenia Valverde; Barbara Benson; Mihir Gupta; Kalpna Gupta
Journal:  Haematologica       Date:  2015-11-06       Impact factor: 9.941

2.  Knockout-transgenic mouse model of sickle cell disease.

Authors:  T M Ryan; D J Ciavatta; T M Townes
Journal:  Science       Date:  1997-10-31       Impact factor: 47.728

3.  Calpain-1 contributes to IgE-mediated mast cell activation.

Authors:  Zhengli Wu; Xiaochun Chen; Fang Liu; Wei Chen; Ping Wu; Adam J Wieschhaus; Athar H Chishti; Paul A Roche; Wei-Min Chen; Tong-Jun Lin
Journal:  J Immunol       Date:  2014-04-23       Impact factor: 5.422

4.  Disruption of the mouse mu-calpain gene reveals an essential role in platelet function.

Authors:  M Azam; S S Andrabi; K E Sahr; L Kamath; A Kuliopulos; A H Chishti
Journal:  Mol Cell Biol       Date:  2001-03       Impact factor: 4.272

5.  Pain-related behaviors and neurochemical alterations in mice expressing sickle hemoglobin: modulation by cannabinoids.

Authors:  Divyanshoo R Kohli; Yunfang Li; Sergey G Khasabov; Pankaj Gupta; Lois J Kehl; Marna E Ericson; Julia Nguyen; Vinita Gupta; Robert P Hebbel; Donald A Simone; Kalpna Gupta
Journal:  Blood       Date:  2010-03-19       Impact factor: 22.113

6.  Mast cell activation contributes to sickle cell pathobiology and pain in mice.

Authors:  Lucile Vincent; Derek Vang; Julia Nguyen; Mihir Gupta; Kathryn Luk; Marna E Ericson; Donald A Simone; Kalpna Gupta
Journal:  Blood       Date:  2013-06-17       Impact factor: 22.113

7.  Acute inhibition of Ca2+/calmodulin-dependent protein kinase II reverses experimental neuropathic pain in mice.

Authors:  Yan Chen; Fang Luo; Cheng Yang; Chelsea M Kirkmire; Zaijie Jim Wang
Journal:  J Pharmacol Exp Ther       Date:  2009-05-28       Impact factor: 4.030

8.  Cannabinoid receptor-specific mechanisms to alleviate pain in sickle cell anemia via inhibition of mast cell activation and neurogenic inflammation.

Authors:  Lucile Vincent; Derek Vang; Julia Nguyen; Barbara Benson; Jianxun Lei; Kalpna Gupta
Journal:  Haematologica       Date:  2015-12-24       Impact factor: 9.941

9.  Pharmacological inhibition of calpain-1 prevents red cell dehydration and reduces Gardos channel activity in a mouse model of sickle cell disease.

Authors:  Lucia De Franceschi; Robert S Franco; Mariarita Bertoldi; Carlo Brugnara; Alessandro Matté; Angela Siciliano; Adam J Wieschhaus; Athar H Chishti; Clinton H Joiner
Journal:  FASEB J       Date:  2012-10-19       Impact factor: 5.191

10.  N-methyl-D-aspartate receptor- and calpain-mediated proteolytic cleavage of K+-Cl- cotransporter-2 impairs spinal chloride homeostasis in neuropathic pain.

Authors:  Hong-Yi Zhou; Shao-Rui Chen; Hee-Sun Byun; Hong Chen; Li Li; Hee-Dong Han; Gabriel Lopez-Berestein; Anil K Sood; Hui-Lin Pan
Journal:  J Biol Chem       Date:  2012-08-01       Impact factor: 5.157
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  9 in total

Review 1.  Targeting novel mechanisms of pain in sickle cell disease.

Authors:  Huy Tran; Mihir Gupta; Kalpna Gupta
Journal:  Blood       Date:  2017-11-30       Impact factor: 22.113

Review 2.  Targeting pain at its source in sickle cell disease.

Authors:  Kanika Gupta; Om Jahagirdar; Kalpna Gupta
Journal:  Am J Physiol Regul Integr Comp Physiol       Date:  2018-03-28       Impact factor: 3.619

Review 3.  Targeting novel mechanisms of pain in sickle cell disease.

Authors:  Huy Tran; Mihir Gupta; Kalpna Gupta
Journal:  Hematology Am Soc Hematol Educ Program       Date:  2017-12-08

4.  Calpain-1 inhibition attenuates in vivo thrombosis in a humanized model of sickle cell disease.

Authors:  Farha Mithila; Christopher Schwake; Chao Fang; Glenn Merrill-Skoloff; Lidija Covic; Daniel I Fritz; Toshihiko Hanada; Robert Flaumenhaft; Athar H Chishti
Journal:  Thromb Res       Date:  2022-02-04       Impact factor: 10.407

5.  Salubrinal induces fetal hemoglobin expression via the stress-signaling pathway in human sickle erythroid progenitors and sickle cell disease mice.

Authors:  Nicole H Lopez; Biaoru Li; Chithra Palani; Umapathy Siddaramappa; Mayuko Takezaki; Hongyan Xu; Wenbo Zhi; Betty S Pace
Journal:  PLoS One       Date:  2022-05-31       Impact factor: 3.752

6.  Calpain-1 regulates platelet function in a humanized mouse model of sickle cell disease.

Authors:  Jennifer O Nwankwo; Thomas Gremmel; Anja J Gerrits; Farha J Mithila; Rod R Warburton; Nicholas S Hill; Yunzhe Lu; Lauren J Richey; Joseph A Jakubowski; Andrew L Frelinger; Athar H Chishti
Journal:  Thromb Res       Date:  2017-10-26       Impact factor: 3.944

7.  Mechanisms of pain in sickle cell disease.

Authors:  Kensuke Takaoka; Asha Caroline Cyril; Sandhya Jinesh; Rajan Radhakrishnan
Journal:  Br J Pain       Date:  2020-05-22

8.  EphrinB/EphB signaling contributes to spinal nociceptive processing via calpain‑1 and caspase‑3.

Authors:  Mei Yang; Wei Chen; Yu Zhang; Rui Yang; Yiru Wang; Hongbin Yuan
Journal:  Mol Med Rep       Date:  2018-05-09       Impact factor: 2.952

9.  Ex Vivo Activation of Red Blood Cell Senescence by Plasma from Sickle-Cell Disease Patients: Correlation between Markers and Adhesion Consequences during Acute Disease Events.

Authors:  Philippe Chadebech; Gwellaouen Bodivit; Gaétana Di Liberto; Alicia Jouard; Corinne Vasseur; France Pirenne; Pablo Bartolucci
Journal:  Biomolecules       Date:  2021-06-30
  9 in total

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