Literature DB >> 3514233

Effect of cisapride on human fasting gallbladder volume: a real-time ultrasonographic study.

L Marzio, A M DiGiammarco, F Capone, M Neri, A Mezzetti, C Capozzi, F Cuccurullo.   

Abstract

The effect of cisapride, a new non-antidopaminergic agent, on human gallbladder volume has been studied in nine normal subjects. In a double-blind crossover fashion, each subject was given a slow i.v. injection of cisapride and placebo after 12-h fasting. Gallbladder volume was monitored every 15 min for 90 min by real-time ultrasonography. After cisapride, gallbladder volume significantly diminished, with a mean reduction of 22.9 +/- 5%, observed 30 min after injection, whereas no significant changes were noted after placebo. A cholinergic mechanism is proposed to explain the effect of cisapride on gallbladder volume.

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Year:  1986        PMID： 3514233     DOI： 10.1007/bf00635906

Source DB:  PubMed          Journal:  Eur J Clin Pharmacol        ISSN： 0031-6970            Impact factor:   2.953


  6 in total

1.  Gallbladder volume and contractility after truncal, selective and highly selective (parietal-cell) vagotomy in man.

Authors:  G J Parkin; R B Smith; D Johnston
Journal:  Ann Surg       Date:  1973-11       Impact factor: 12.969

2.  A critical evaluation of real-time ultrasonography for the study of gallbladder volume and contraction.

Authors:  G T Everson; D Z Braverman; M L Johnson; F Kern
Journal:  Gastroenterology       Date:  1980-07       Impact factor: 22.682

3.  Gallbladder function in the human female: effect of the ovulatory cycle, pregnancy, and contraceptive steroids.

Authors:  G T Everson; C McKinley; M Lawson; M Johnson; F Kern
Journal:  Gastroenterology       Date:  1982-04       Impact factor: 22.682

4.  Release of cholecystokinin in man: correlation of blood levels with gallbladder contraction.

Authors:  I Wiener; K Inoue; C J Fagan; P Lilja; L C Watson; J C Thompson
Journal:  Ann Surg       Date:  1981-09       Impact factor: 12.969

5.  Effects of pregnancy and contraceptive steroids on gallbladder function.

Authors:  D Z Braverman; M L Johnson; F Kern
Journal:  N Engl J Med       Date:  1980-02-14       Impact factor: 91.245

6.  Atropine antagonizes cholecystokinin and cerulein-induced gallbladder evacuation in man: a real-time ultrasonographic study.

Authors:  L Marzio; A M Di Giammarco; M Neri; F Cuccurullo; P Malfertheiner
Journal:  Am J Gastroenterol       Date:  1985-01       Impact factor: 10.864
  6 in total
  10 in total

Review 1.  Mechanisms of cisapride affecting gallbladder motility.

Authors:  R von Kiedrowski; S Huijghebaert; R Raedsch
Journal:  Dig Dis Sci       Date:  2001-05       Impact factor: 3.199

Review 2.  Cisapride. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use as a prokinetic agent in gastrointestinal motility disorders.

Authors:  R W McCallum; C Prakash; D M Campoli-Richards; K L Goa
Journal:  Drugs       Date:  1988-12       Impact factor: 9.546

Review 3.  Gall stones and gall bladder motility.

Authors:  L J O'Donnell; P D Fairclough
Journal:  Gut       Date:  1993-04       Impact factor: 23.059

4.  Cisapride inhibits motility of the sphincter of Oddi in the Australian possum.

Authors:  R A Baker; G T Saccone; J Toouli
Journal:  Dig Dis Sci       Date:  1990-06       Impact factor: 3.199

5.  Gallbladder hypokinesia and normal gastric emptying of liquids in patients with dyspeptic symptoms. A double-blind placebo-controlled clinical trial with cisapride.

Authors:  L Marzio; F DiFelice; M G Laico; B Imbimbo; D Lapenna; F Cuccurullo
Journal:  Dig Dis Sci       Date:  1992-02       Impact factor: 3.199

Review 6.  Cisapride. An updated review of its pharmacology and therapeutic efficacy as a prokinetic agent in gastrointestinal motility disorders.

Authors:  L R Wiseman; D Faulds
Journal:  Drugs       Date:  1994-01       Impact factor: 9.546

7.  Effects of cisapride on gallbladder emptying and pancreatic polypeptide and cholecystokinin release in humans.

Authors:  T Meguro; T Shimosegawa; Y Kikuchi; M Koizumi; T Toyota
Journal:  J Gastroenterol       Date:  1995-04       Impact factor: 7.527

8.  Effect of cisapride on gallbladder emptying and plasma CCK in normal and vagotomized human subjects.

Authors:  R Patankar; M M Ozmen; A Sanderson; C D Johnson
Journal:  Dig Dis Sci       Date:  1996-03       Impact factor: 3.199

Review 9.  Systematic review: cardiovascular safety profile of 5-HT(4) agonists developed for gastrointestinal disorders.

Authors:  J Tack; M Camilleri; L Chang; W D Chey; J J Galligan; B E Lacy; S Müller-Lissner; E M M Quigley; J Schuurkes; J H De Maeyer; V Stanghellini
Journal:  Aliment Pharmacol Ther       Date:  2012-02-22       Impact factor: 8.171

10.  Effects of tegaserod on bile composition and hepatic secretion in Richardson ground squirrels on an enriched cholesterol diet.

Authors:  Ronald Mathison; Eldon Shaffer; Hans-Juergen Pfannkuche; David Earnest
Journal:  Lipids Health Dis       Date:  2006-06-22       Impact factor: 3.876
  10 in total

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