Literature DB >> 3514010

The effect of gluten on HLA-DR in the small intestinal epithelium of patients with coeliac disease.

P J Ciclitira, J M Nelufer, H J Ellis, D J Evans.   

Abstract

Frozen sections of control and coeliac jejunal mucosa were examined for HLA-DR staining. In general the staining pattern in the controls and treated coeliac patients was a patchy subapical pattern on villous tips. Untreated coeliac patients gave a different pattern with staining extending to the crypt enterocytes. Gluten challenge in three treated coeliac patients induced an altered staining pattern within 2 h.

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Year:  1986        PMID： 3514010      PMCID： PMC1577323     

Source DB:  PubMed          Journal:  Clin Exp Immunol        ISSN： 0009-9104            Impact factor:   4.330


  6 in total

Review 1.  Human lymphocyte antigens: a mini review.

Authors:  P M Lydyard; P Banga; G Guarnotta; P Walker; L Mackenzie; S Markanday
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2.  HLA-DR-like antigens in the epithelium of the human small intestine.

Authors:  H Scott; B G Solheim; P Brandtzaeg; E Thorsby
Journal:  Scand J Immunol       Date:  1980       Impact factor: 3.487

3.  Clinical testing of gliadin fractions in coeliac patients.

Authors:  P J Ciclitira; D J Evans; N L Fagg; E S Lennox; R H Dowling
Journal:  Clin Sci (Lond)       Date:  1984-03       Impact factor: 6.124

4.  Clinical testing of bread made from nullisomic 6A wheats in coeliac patients.

Authors:  P J Ciclitira; J O Hunter; E S Lennox
Journal:  Lancet       Date:  1980-08-02       Impact factor: 79.321

5.  Expression of HLA-DR (Ia like) antigen on epidermal keratinocytes in human dermatoses.

Authors:  I A Lampert
Journal:  Clin Exp Immunol       Date:  1984-07       Impact factor: 4.330

6.  Immunohistochemical techniques in the early screening of monoclonal antibodies to human colonic epithelium.

Authors:  P J Finan; R M Grant; C de Mattos; F Takei; P J Berry; E S Lennox; N M Bleehen
Journal:  Br J Cancer       Date:  1982-07       Impact factor: 7.640
  6 in total
  14 in total

Review 1.  Emerging technologies in upper gastrointestinal endoscopy and celiac disease.

Authors:  Giovanni Cammarota; Paolo Fedeli; Antonio Gasbarrini
Journal:  Nat Clin Pract Gastroenterol Hepatol       Date:  2008-11-11

2.  Highly polarized HLA class II antigen processing and presentation by human intestinal epithelial cells.

Authors:  R M Hershberg; D H Cho; A Youakim; M B Bradley; J S Lee; P E Framson; G T Nepom
Journal:  J Clin Invest       Date:  1998-08-15       Impact factor: 14.808

3.  Intestinal epithelial cells use two distinct pathways for HLA class II antigen processing.

Authors:  R M Hershberg; P E Framson; D H Cho; L Y Lee; S Kovats; J Beitz; J S Blum; G T Nepom
Journal:  J Clin Invest       Date:  1997-07-01       Impact factor: 14.808

4.  Early biochemical responses of the small intestine of coeliac patients to wheat gluten.

Authors:  D S Bailey; A R Freedman; S C Price; D Chescoe; P J Ciclitira
Journal:  Gut       Date:  1989-01       Impact factor: 23.059

5.  Immunoperoxidase demonstration of the cellular composition of the normal and coeliac small bowel.

Authors:  J Kelly; C O'Farrelly; C O'Mahony; D G Weir; C Feighery
Journal:  Clin Exp Immunol       Date:  1987-04       Impact factor: 4.330

6.  Analysis of RNA transcripts for HLA class II genes in human small intestinal biopsies.

Authors:  B A Volk; D A Brenner; M F Kagnoff
Journal:  Gut       Date:  1989-09       Impact factor: 23.059

7.  Gliadin induced changes in the expression of MHC-class II antigens by human small intestinal epithelium. Organ culture studies with coeliac disease mucosa.

Authors:  S Fais; L Maiuri; F Pallone; M De Vincenzi; G De Ritis; R Troncone; S Auricchio
Journal:  Gut       Date:  1992-04       Impact factor: 23.059

8.  Sequential induction of MHC antigens on autochthonous cells of ileum affected by Crohn's disease.

Authors:  K Koretz; F Momburg; H F Otto; P Möller
Journal:  Am J Pathol       Date:  1987-12       Impact factor: 4.307

9.  HLA-DR, DP and DQ expression in the small intestine of patients with coeliac disease.

Authors:  N J Marley; J C Macartney; P J Ciclitira
Journal:  Clin Exp Immunol       Date:  1987-11       Impact factor: 4.330

10.  Effect of gliadin and other food peptides on expression of MHC class II molecules by HT-29 cells.

Authors:  T Mothes; U Bendix; C Pfannschmidt; I Lehmann
Journal:  Gut       Date:  1995-04       Impact factor: 23.059
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