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Literature DB >> 3513961

Immunohistochemical demonstration of histamine N-methyltransferase-like structures in rat kidney.

H Fukuda, H Kiyama, K Maeyama, H Kubota, A Yamatodani, T Watanabe, M Tohyama, H Wada.

Abstract

Histamine N-methyltransferase (S-adenosylmethionine: histamine N-methyltransferase, E.C. 2.1.1.8) was purified to homogeneity from rat kidney, and antibody was raised against it in guinea pigs. The antibody immunoprecipitated histamine N-methyltransferase. Immunofluorescent histochemical studies with anti-histamine N-methyltransferase antibody as the first antibody and goat anti-guinea pig IgG conjugated with fluorescein isothiocyanate as the second, showed the presence of immunoreactive structures in the proximal tubules of rat kidney. The brain showed no immunoreaction with the antibody.

Entities: Chemical Gene Species

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Year: 1986 PMID： 3513961 DOI： 10.1007/bf00218079

Source DB: PubMed Journal: Cell Tissue Res ISSN： 0302-766X Impact factor: 5.249

16 in total

1. The distribution and properties of a histamine-methylating enzyme.

Authors: D D BROWN; R TOMCHICK; J AXELROD
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2. Fluorescent antibody methods.

Authors: A H COONS
Journal: Gen Cytochem Methods Date: 1958

3. Cleavage of structural proteins during the assembly of the head of bacteriophage T4.

Authors: U K Laemmli
Journal: Nature Date: 1970-08-15 Impact factor: 49.962

4. The reliability of molecular weight determinations by dodecyl sulfate-polyacrylamide gel electrophoresis.

Authors: K Weber; M Osborn
Journal: J Biol Chem Date: 1969-08-25 Impact factor: 5.157

5. Evidence for a less high acceptor substrate specificity of gastric histamine methyltransferase: methylation of imidazole compounds.

Authors: H Barth; M Crombach; W Schunack; W Lorenz
Journal: Biochem Pharmacol Date: 1980-05-15 Impact factor: 5.858

10. O-phthalaldehyde: fluorogenic detection of primary amines in the picomole range. Comparison with fluorescamine and ninhydrin.

Authors: J R Benson; P E Hare
Journal: Proc Natl Acad Sci U S A Date: 1975-02 Impact factor: 11.205

1 in total

1. Distribution of histamine in the rat kidney during pregnancy and development.

Authors: M J Nissinen; E Castrèn; H Holthöfer; P Panula
Journal: Cell Tissue Res Date: 1992-02 Impact factor: 5.249

1 in total

Immunohistochemical demonstration of histamine N-methyltransferase-like structures in rat kidney.

1. The distribution and properties of a histamine-methylating enzyme.

2. Fluorescent antibody methods.

3. Cleavage of structural proteins during the assembly of the head of bacteriophage T4.

4. The reliability of molecular weight determinations by dodecyl sulfate-polyacrylamide gel electrophoresis.

5. Evidence for a less high acceptor substrate specificity of gastric histamine methyltransferase: methylation of imidazole compounds.

6. Rat and mouse brain histamine N-methyltransferase: modulation by methylated indoleamines.

7. Rat histamine N-methyltransferase. Quantification, tissue distribution, purification, and immunologic properties.

8. Guinea pig brain histamine N-methyltransferase: purification and partial characterization.

9. A new radioenzymatic assay for histamine using purified histamine N-methyltransferase.

10. O-phthalaldehyde: fluorogenic detection of primary amines in the picomole range. Comparison with fluorescamine and ninhydrin.

1. Distribution of histamine in the rat kidney during pregnancy and development.