Ray Portela1, Katie Marrerro2, Ahmet Vahibe1, Carlos Galvani3, Helmuth Billy4, Barham Abu Dayyeh5, Benjamin Clapp6, Omar M Ghanem7. 1. Department of Surgery, Mayo Clinic, Rochester, MN, 55905, USA. 2. Carle Foundation Hospital General Surgery Residency, Champaign, IL, USA. 3. Department of Surgery, Tulane School of Medicine, New Orleans, LA, USA. 4. Ventura Advanced Surgical Associates, Ventura, CA, USA. 5. Department of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, 55905, USA. 6. Department of Surgery, Texas Tech HSC Paul Foster School of Medicine, El Paso, TX, USA. 7. Department of Surgery, Mayo Clinic, Rochester, MN, 55905, USA. Ghanem.Omar@Mayo.Edu.
Abstract
BACKGROUND: Single anastomosis duodenal-ileal bypass with sleeve (SADI-S) is a novel bariatric surgery modified from the classic biliopancreatic diversion with duodenal switch (BPD-DS). These surgical modifications address most BPD-DS hurdles, but the risk of bile reflux may hinder SADI-S acceptance. We aimed to evaluate the event rate of bile reflux after SADI-S. METHODS: PubMed, ScienceDirect, Cochrane, Web of Science, and Google Scholar were used to search English articles between 2008 and 2021 by two independent reviewers using the Preferred Reporting Items for Systematic Reviews and Meta-analysis (PRISMA). The risk of bias was assessed using Newcastle-Ottawa Scale and the JBI tool. Event rates were meta-analyzed using Comprehensive Meta-Analysis (CME) V3. RESULTS: Out of 3,027 studies analyzed, seven were included. Studies were published between 2010 and 2020. Six out of 7 studies were retrospective. Three studies had a low risk of bias, three studies had a moderate risk of bias, and one had a high risk of bias. The mean follow-up was 10.3 months. The total number of patients was 2,029, with 25 reports of bile reflux, resulting in an incidence of 1.23%, with an event rate of 0.016 (95% CI 0.004 to 0.055). CONCLUSIONS: Bile reflux has not been demonstrated to be problematic after SADI-S in this meta-analysis. Further long-term studies are needed.
BACKGROUND: Single anastomosis duodenal-ileal bypass with sleeve (SADI-S) is a novel bariatric surgery modified from the classic biliopancreatic diversion with duodenal switch (BPD-DS). These surgical modifications address most BPD-DS hurdles, but the risk of bile reflux may hinder SADI-S acceptance. We aimed to evaluate the event rate of bile reflux after SADI-S. METHODS: PubMed, ScienceDirect, Cochrane, Web of Science, and Google Scholar were used to search English articles between 2008 and 2021 by two independent reviewers using the Preferred Reporting Items for Systematic Reviews and Meta-analysis (PRISMA). The risk of bias was assessed using Newcastle-Ottawa Scale and the JBI tool. Event rates were meta-analyzed using Comprehensive Meta-Analysis (CME) V3. RESULTS: Out of 3,027 studies analyzed, seven were included. Studies were published between 2010 and 2020. Six out of 7 studies were retrospective. Three studies had a low risk of bias, three studies had a moderate risk of bias, and one had a high risk of bias. The mean follow-up was 10.3 months. The total number of patients was 2,029, with 25 reports of bile reflux, resulting in an incidence of 1.23%, with an event rate of 0.016 (95% CI 0.004 to 0.055). CONCLUSIONS: Bile reflux has not been demonstrated to be problematic after SADI-S in this meta-analysis. Further long-term studies are needed.
Authors: Benjamin Clapp; Joseph N Badaoui; Jesus A Gamez; Andres Vivar; Omar M Ghanem Journal: Surg Obes Relat Dis Date: 2021-07-06 Impact factor: 4.734
Authors: Joseph N Badaoui; Todd A Kellogg; Barham K Abu Dayyeh; Justin W Maroun; Travis J McKenzie; William S Harmsen; Michael L Kendrick; Omar M Ghanem Journal: Obes Surg Date: 2021-07-22 Impact factor: 4.129
Authors: Amit Surve; Daniel Cottam; Walter Medlin; Christina Richards; Legrand Belnap; Benjamin Horsley; Samuel Cottam; Austin Cottam Journal: Surg Obes Relat Dis Date: 2020-07-31 Impact factor: 4.734
Authors: Dan Li; Jian Zhang; Wen Zhu Yao; Dong Lin Zhang; Chen Chen Feng; Qi He; Huan Huan Lv; Ya Ping Cao; Jie Wang; Ying Qi; Si Ran Wu; Na Wang; Jing Zhao; Yong Quan Shi Journal: J Dig Dis Date: 2020-04-21 Impact factor: 2.325