| Literature DB >> 35130422 |
Qiang Jian1, Zhenlei Liu1, Wanru Duan1, Jian Guan1, Fengzeng Jian1, Zan Chen1.
Abstract
OBJECTIVE: This study aimed to investigate the outcome of using 3-dimensional (3D)-printed prostheses to reconstruct a cervical lateral mass to maintain cervical stability.Entities:
Keywords: Axis; Lateral mass; Prothesis; Subaxial cervical spine; Three-dimensional printing
Year: 2022 PMID: 35130422 PMCID: PMC8987545 DOI: 10.14245/ns.2143008.504
Source DB: PubMed Journal: Neurospine ISSN: 2586-6591
Seven patients with lateral mass reconstruction
| Case No. | Age (yr)/sex | Lesion | Lateral mass span | Reconstruction material | Clinical manifestation | Preoperative JOA score | Follow-up (mo) | Adjuvant therapy | Complication | JOA score at final follow-up |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 63/M | C2 chordoma | Bilateral C2 | 3D-printed titanium alloy prosthesis | Neck pain, shoulder pain, dysphagia | 15 | 32 | Radiation therapy | Dysphagia after radiotherapy | 17 |
| 2 | 73/M | C2 chordoma | Right C2[ | 3D-printed titanium alloy prosthesis | Neck pain, dysphagia | 15 | 9 | None | None | 17 |
| 3 | 16/M | C6-7 chordoma | Right C6–7 | 3D-printed titanium alloy prosthesis | Upper limb pain | 14 | 14 | None | Recurrence | 16 |
| 4 | 62/F | C6-7 metastasis | Left C6–7 | 3D-printed titanium alloy prosthesis | Upper limb pain and weakness | 15 | 5 | Chemotherapy | None | 16 |
| 5 | 49/M | C3/4 dumbbell schwannoma | Right C3–4 | 3D-printed titanium alloy prosthesis | Upper limb numbness | 16 | 6 | None | None | 17 |
| 6 | 28/M | C6-7 dumbbell schwannoma | Right C6–7 | 3D-printed titanium alloy prosthesis | Upper limb pain | 15 | 4 | None | None | 17 |
| 7 | 42/F | C6-7 schwannoma | Left C6–7 | 3D-printed titanium alloy prosthesis | Limb numbness | 14 | 3 | None | None | 16 |
JOA, Japanese Orthopedic Association; 3D, 3-dimensional.
Matching error.
Fig. 1.Imaging findings for case number 1. Sagittal contrast-enhanced magnetic resonance imaging (MRI) (A) and axial T2-weighted MRI (B) showing an axial tumor (Enneking stage IIB). The Weinstein-Boriani-Biagini stages were 5–10, A–D. Preoperative puncture pathology indicated chordoma. (C) A preoperative design of the 3-dimensional-printed axial lateral mass (LM) prosthesis. (D) An intraoperative image shows the implantation of the posterior LM prosthesis. (E) A postoperative sagittal computed tomography scan of the reconstruction shows that the LM prosthesis is in a good position and that the anterior screw was inserted into the anterior column and LM prostheses. (F) Postoperative sagittal T2-weighted MRI indicates good spinal canal volume. Postoperative lateral (G) and anteroposterior (H) radiographs of the cervical spine show that the LM prosthesis is well positioned.
Fig. 2.Imaging findings for case number 3. (A, B) Preoperative contrast-enhanced sagittal and axial T2-weighted magnetic resonance imaging shows a dumbbell tumor with C6/7 vertebral body involvement. Preoperative biopsy pathology indicated chordoma. (C) The lateral mass (LM) prosthesis was preoperatively designed based on the patient’s computed tomography (CT) data, and (D) the 3D-printed LM prosthesis was manufactured. (E) The first-stage posterior approach was used to remove the intraspinal tumor and reconstruct the LM structure. (F) A coronal CT scan of the reconstruction at 6 postoperative months shows that the LM prosthesis is in a good position. Dynamic radiographs taken in extension (G) and flexion (H) showed the stability of the implant.
Fig. 3.Imaging findings for case number 4. Enhanced sagittal (A) and axial T2-weighted (B) magnetic resonance imaging findings indicate left dumbbell tumors at C6/7 and C7/T1. (C) Tumor infiltration of the nerve root was observed intraoperatively, and (D) a lateral mass prosthesis was implanted following tumor resection. Postoperative lateral cervical radiograph (E) and sagittal computed tomography scan images of the reconstruction (F) show that the prosthesis was well positioned and that it was highly matched with the surrounding structures.
Literature review concerning lateral mass reconstruction
| Study | Age (yr)/sex | Pathology | Lateral mass span | Reconstruction material |
|---|---|---|---|---|
| Bongioanni et al., [ | 36/M | Aneurysmal bone cyst | C1 | An iliac-crest bone graft |
| Suchomel et al., [ | 62/M | Chordoma | Bilateral C2 | Harms mesh cage |
| Wang et al., [ | 12/F | Aneurysmal bone cyst | Bilateral C1 | Titanium mesh cage, rib graft |
| Chung et al., [ | 48/M | Osteosarcoma | C1 | Titanium mesh cage |
| Jandial et al., [ | 27/M | Metastatic Ewing sarcoma | Bilateral C1 | Expandable cages |
| Winking, [ | 54/F | Nodular plasmocytoma | C1 | Harms cage |
| Bobinski et al., [ | 48/F | Angiosarcoma | C1 | 2 Titanium cages |
| 54/M | Multiple myeloma | C1 | Titanium cage | |
| Clarke et al., [ | 35/M | Chordoma | Oc–C3 | Titanium mesh cage |
| 60/F | Chondrosarcoma | C1–6 | Titanium mesh cage | |
| 50/M | Epithelioid schwannoma | Oc–C3 | Titanium mesh cage | |
| 61/F | Dumbbell schwannoma | C3–5 | Titanium mesh cage | |
| 77/F | Chordoma | Left, Oc–C4; Right, Oc–C3 | Titanium mesh cage | |
| 16/M | Schwannoma | C6–T1 | Fibular strut | |
| 25/M | Osteochondroma | C3–6 | Fibular strut | |
| Clarke et al., [ | 8/F | Osteosarcoma | Bilateral C1 | Allograft fibular strut |
| Peciu-Florianu et al., [ | 12/M | Osteoblastoma | Bilateral C1 | Titanium cages |
| Stephens and Wright, [ | 27/M | Eosinophilic granuloma | C1 | A titanium expandable cage |
| Neva et al., [ | 18/F | Aneurysmal bone cyst | C1 | Static titanium cage |
| Ji et al., [ | 50/F | Schwannoma | C3–4 | A strip of shaped allograft bone |