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Literature DB >> 3512443

Infection of gnotobiotic pigs with an Escherichia coli O157:H7 strain associated with an outbreak of hemorrhagic colitis.

Abstract

Gnotobiotic pigs inoculated with an Escherichia coli O157:H7 strain isolated from a human with hemorrhagic colitis developed anorexia, lethargy, and watery diarrhea. Bacteria diffusely colonized the cecum and colon surfaces and the crypt epithelium. At bacterial attachment sites, microvilli were effaced, and epithelial cells were irregularly shaped, rounded, or detached. Submucosa, lamina propria, and mesentery were markedly edematous and contained many inflammatory cells.

Entities: Disease Species

Mesh：

Year: 1986 PMID： 3512443 PMCID： PMC260992 DOI： 10.1128/iai.51.3.953-956.1986

Source DB: PubMed Journal: Infect Immun ISSN： 0019-9567 Impact factor: 3.441

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