Literature DB >> 3511900

A method for determining the intracellular distribution of enzymes in yeast provides no evidence for the association of hexokinase with mitochondria.

L Kovác, B D Nelson, L Ernster.   

Abstract

A simple procedure based upon the principle discovered by Dürr et al. (Arch. Microbiol. (1975) 105, 319-327) was used to measure the intracellular distribution of enzymes in S. cerevisiae grown under both glucose repression and derepression. No substantial hexokinase activity was found to be associated with cellular organelles. The result does not support the hypotheses that reversible binding of hexokinase to mitochondria is important in regulation of glycolysis and cell growth.

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Year:  1986        PMID: 3511900     DOI: 10.1016/0006-291x(86)90560-7

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN: 0006-291X            Impact factor:   3.575


  8 in total

1.  Binding of rat brain hexokinase to recombinant yeast mitochondria: effect of environmental factors and the source of porin.

Authors:  C Aflalo; H Azoulay
Journal:  J Bioenerg Biomembr       Date:  1998-06       Impact factor: 2.945

2.  Localized firefly luciferase probes ATP at the surface of mitochondria.

Authors:  C Aflalo
Journal:  J Bioenerg Biomembr       Date:  1997-12       Impact factor: 2.945

3.  Complete amino acid sequence of rat brain hexokinase, deduced from the cloned cDNA, and proposed structure of a mammalian hexokinase.

Authors:  D A Schwab; J E Wilson
Journal:  Proc Natl Acad Sci U S A       Date:  1989-04       Impact factor: 11.205

Review 4.  Homologous and heterologous interactions between hexokinase and mitochondrial porin: evolutionary implications.

Authors:  J E Wilson
Journal:  J Bioenerg Biomembr       Date:  1997-02       Impact factor: 2.945

5.  19F NMR measurements of the rotational mobility of proteins in vivo.

Authors:  S P Williams; P M Haggie; K M Brindle
Journal:  Biophys J       Date:  1997-01       Impact factor: 4.033

6.  Hexokinase production from S. cerevisiae. Culture conditions.

Authors:  J Abrahão-Neto; P Infanti; M Vitolo
Journal:  Appl Biochem Biotechnol       Date:  1996       Impact factor: 2.926

7.  Synthetic lethality between eIF5A and Ypt1 reveals a connection between translation and the secretory pathway in yeast.

Authors:  Mariana C Frigieri; Marcus V S João Luiz; Luciano H Apponi; Cleslei F Zanelli; Sandro R Valentini
Journal:  Mol Genet Genomics       Date:  2008-06-21       Impact factor: 3.291

8.  Structural basis of complex formation between mitochondrial anion channel VDAC1 and Hexokinase-II.

Authors:  Nandan Haloi; Po-Chao Wen; Qunli Cheng; Meiying Yang; Gayathri Natarajan; Amadou K S Camara; Wai-Meng Kwok; Emad Tajkhorshid
Journal:  Commun Biol       Date:  2021-06-03
  8 in total

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