Literature DB >> 3511775

Clinical and pharmacokinetic concerns of 24-hour dosing with theophylline.

M Weinberger.   

Abstract

Selection of the dosing interval for oral theophylline must consider the product's absorption rate, the patient's elimination rate, and the tolerated fluctuation in serum concentration. Attempts to produce formulations with ultra-slow absorption for "once daily" marketing have thus far resulted in incomplete and erratic absorption.

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Year:  1986        PMID： 3511775

Source DB:  PubMed          Journal:  Ann Allergy        ISSN： 0003-4738


  3 in total

1.  The effect of dosing time on the pharmacokinetics and pharmacodynamics of a 'once-a-day' sustained release theophylline preparation.

Authors:  H Lamont; R Pauwels; M Van der Straeten
Journal:  Br J Clin Pharmacol       Date:  1987-12       Impact factor: 4.335

2.  Once-daily theophylline in the treatment of nocturnal asthma.

Authors:  V Vilkka; P Brander; A Hakulinen; J Laitinen; K Sahlström; E Aalto; M Silvasti; P Karttunen
Journal:  Eur J Clin Pharmacol       Date:  1990       Impact factor: 2.953

Review 3.  Food interactions with sustained-release theophylline preparations. A review.

Authors:  J H Jonkman
Journal:  Clin Pharmacokinet       Date:  1989-03       Impact factor: 6.447
  3 in total

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