Literature DB >> 35110902

Adequate Assessment Can Affect the Management of Breast Cancer in Geriatric Population.

Sherif Monib1, Mohamed Elkorety1, Hany Habashy2.   

Abstract

Breast cancer (BC) risk increases with age; about a third of patients are diagnosed in age older than 65. Treatment of this age group remains controversial, leading to inferior outcomes with lower survival rates than younger patients. We aimed to evaluate performance status tools as well as the outcome of management of breast cancer in the geriatric population. We have conducted a retrospective database analysis looking into the management of breast cancer patients older than 65 years old presenting to our unit during the period between June 2015 and June 2019. All patients had triple assessment as well as multimodality performance status assessment with their treatment modalities, and outcomes are recorded and assessed. We have included 578 patients, 0.8% male and 99.2% female, and our patients' mean age was 71 years. Most of our patients scored one or two on the WHO/ECOG performance status score and Clinical Frailty Score, as well as ASA-PS score. 3.2% had no treatment, 4.3% had endocrine therapy only, 0.5% had primary endocrine therapy followed by surgery, and 92.3% underwent surgery with 4.1% complication rate. Patients who underwent breast-conserving surgery had adjuvant breast radiotherapy, and 23.7% had adjuvant chest wall radiotherapy, 78.8% had adjuvant endocrine treatment, and 4.8% had adjuvant chemotherapy out of which 30.7% had adjuvant chemotherapy and Herceptin. Objective assessment tools should be used for patients older than 65 years diagnosed with primary breast cancer to be able to scarify patients' individualised treatment options to reach the optimum outcome. © Indian Association of Surgical Oncology 2021.

Entities:  

Keywords:  Assessment; Breast cancer; Geriatric

Year:  2021        PMID: 35110902      PMCID: PMC8763989          DOI: 10.1007/s13193-021-01442-1

Source DB:  PubMed          Journal:  Indian J Surg Oncol        ISSN: 0975-7651


  23 in total

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Journal:  Breast Cancer Res Treat       Date:  2019-09-06       Impact factor: 4.872

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