Literature DB >> 35106045

Advancing Inclusive Research: Establishing Collaborative Strategies to Improve Diversity in Clinical Trials.

Owen Garrick1, Ruben Mesa2, Andrea Ferris3, Edward S Kim4, Edith Mitchell5, Otis W Brawley6, John Carpten7, Keith D Carter8, Joseph Coney9, Robert Winn10, Stephanie Monroe11, Fabian Sandoval12, Edith Perez13, Mitzi Williams14, Evan Grove15, Quita Highsmith16, Nicole Richie16, Susan M Begelman16, Asha S Collins16, Jamie Freedman16, Melissa S Gonzales16, Gerren Wilson16.   

Abstract

Well-characterized disparities in clinical research have disproportionately affected patients of color, particularly in underserved communities. To tackle these barriers, Genentech formed the External Council for Advancing Inclusive Research, a 14-person committee dedicated to developing strategies to increase clinical research participation. To help improve the recruitment and retention of patients of color, this article chronicles our efforts to tangibly address the clinical research barriers at the system, study, and patient levels over the last four years. These efforts are one of the initial steps to fully realize the promise of personalized health care and provide increased patient benefit at less cost to society. Instead of simply acknowledging the problem, here we illuminate the collaborative and multilevel strategies that have been effective in delivering meaningful progress for patients.
Copyright © 2022, Ethnicity & Disease, Inc.

Entities:  

Keywords:  COVID-19; Clinical Trial Design; Health Care Disparities; Minority Health; Personalized Health Care

Year:  2022        PMID: 35106045      PMCID: PMC8785867          DOI: 10.18865/ed.32.1.61

Source DB:  PubMed          Journal:  Ethn Dis        ISSN: 1049-510X            Impact factor:   2.006


  17 in total

1.  Minority physicians' role in the care of underserved patients: diversifying the physician workforce may be key in addressing health disparities.

Authors:  Lyndonna M Marrast; Leah Zallman; Steffie Woolhandler; David H Bor; Danny McCormick
Journal:  JAMA Intern Med       Date:  2014-02-01       Impact factor: 21.873

2.  The Role of Clinical Trial Participation in Cancer Research: Barriers, Evidence, and Strategies.

Authors:  Joseph M Unger; Elise Cook; Eric Tai; Archie Bleyer
Journal:  Am Soc Clin Oncol Educ Book       Date:  2016

3.  Barriers to Clinical Trial Enrollment in Racial and Ethnic Minority Patients With Cancer.

Authors:  Lauren M Hamel; Louis A Penner; Terrance L Albrecht; Elisabeth Heath; Clement K Gwede; Susan Eggly
Journal:  Cancer Control       Date:  2016-10       Impact factor: 3.302

4.  Multiple sclerosis in US minority populations: Clinical practice insights.

Authors:  Omar Khan; Mitzi J Williams; Lilyana Amezcua; Adil Javed; Kristin E Larsen; Jennifer M Smrtka
Journal:  Neurol Clin Pract       Date:  2015-04

Review 5.  Overcoming Barriers to Clinical Trial Enrollment.

Authors:  Ryan D Nipp; Kessely Hong; Electra D Paskett
Journal:  Am Soc Clin Oncol Educ Book       Date:  2019-05-17

6.  Dialogues on diversifying clinical trials: successful strategies for engaging women and minorities in clinical trials.

Authors:  Meghan Coakley; Emmanuel Olutayo Fadiran; L Jo Parrish; Rachel A Griffith; Eleanor Weiss; Christine Carter
Journal:  J Womens Health (Larchmt)       Date:  2012-07       Impact factor: 2.681

7.  Broadening Eligibility Criteria to Make Clinical Trials More Representative: American Society of Clinical Oncology and Friends of Cancer Research Joint Research Statement.

Authors:  Edward S Kim; Suanna S Bruinooge; Samantha Roberts; Gwynn Ison; Nancy U Lin; Lia Gore; Thomas S Uldrick; Stuart M Lichtman; Nancy Roach; Julia A Beaver; Rajeshwari Sridhara; Paul J Hesketh; Andrea M Denicoff; Elizabeth Garrett-Mayer; Eric Rubin; Pratik Multani; Tatiana M Prowell; Caroline Schenkel; Marina Kozak; Jeff Allen; Ellen Sigal; Richard L Schilsky
Journal:  J Clin Oncol       Date:  2017-10-02       Impact factor: 44.544

8.  Tocilizumab in Patients Hospitalized with Covid-19 Pneumonia.

Authors:  Carlos Salama; Jian Han; Linda Yau; William G Reiss; Benjamin Kramer; Jeffrey D Neidhart; Gerard J Criner; Emma Kaplan-Lewis; Rachel Baden; Lavannya Pandit; Miriam L Cameron; Julia Garcia-Diaz; Victoria Chávez; Martha Mekebeb-Reuter; Ferdinando Lima de Menezes; Reena Shah; Maria F González-Lara; Beverly Assman; Jamie Freedman; Shalini V Mohan
Journal:  N Engl J Med       Date:  2020-12-17       Impact factor: 91.245

Review 9.  Modernizing Clinical Trial Eligibility Criteria: Recommendations of the ASCO-Friends of Cancer Research Laboratory Reference Ranges and Testing Intervals Work Group.

Authors:  Alexander I Spira; Mark D Stewart; Suzanne Jones; Elaine Chang; Anitra Fielding; Nicole Richie; Laura S Wood; Michael A Thompson; Lee Jones; Abhilasha Nair; Brandon A Mahal; David E Gerber
Journal:  Clin Cancer Res       Date:  2021-02-09       Impact factor: 13.801

10.  Assessment of Training in Health Disparities in US Internal Medicine Residency Programs.

Authors:  Denise M Dupras; Mark L Wieland; Andrew J Halvorsen; Maria Maldonado; Lisa L Willett; Linda Harris
Journal:  JAMA Netw Open       Date:  2020-08-03
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  2 in total

1.  Rationale and design of Children's Oncology Group (COG) study ACCL20N1CD: financial distress during treatment of acute lymphoblastic leukemia in the United States.

Authors:  Melissa Beauchemin; Sheila Judge Santacroce; Kira Bona; Ha Dang; Sarah Alexander; Kamala Allen; Crystal De Los Santos; Beth Fisher; Yudy Muñeton-Castaño; Olivia Ponce; Sarah Vargas; Aaron Sugalski; Lillian Sung; Susan Parsons
Journal:  BMC Health Serv Res       Date:  2022-06-28       Impact factor: 2.908

2.  Social determinants of participant recruitment and retention in a prospective cohort study of pediatric mild traumatic brain injury.

Authors:  Jordee M Wells; Jean-Michel Galarneau; Nori M Minich; Daniel M Cohen; Kameron Clinton; H Gerry Taylor; Erin D Bigler; Ann Bacevice; Leslie K Mihalov; Barbara A Bangert; Nicholas A Zumberge; Keith Owen Yeates
Journal:  Front Neurol       Date:  2022-09-13       Impact factor: 4.086

  2 in total

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