Literature DB >> 35089871

Meeting Report: Aging Research and Drug Discovery.

Esther Meron1, Maria Thaysen1, Suzanne Angeli2, Adam Antebi3, Nir Barzilai4,5, Joseph A Baur6, Simon Bekker-Jensen1, Maria Birkisdottir7,8, Evelyne Bischof9, Jens Bruening10, Anne Brunet11, Abigail Buchwalter12, Filipe Cabreiro13,14, Shiqing Cai15, Brian H Chen16,17, Maria Ermolaeva18, Collin Y Ewald19, Luigi Ferrucci20, Maria Carolina Florian21, Kristen Fortney22, Adam Freund23, Anastasia Georgievskaya24, Vadim N Gladyshev25, David Glass26, Tyler Golato27, Vera Gorbunova28, Jan Hoejimakers29, Riekelt H Houtkooper30, Sibylle Jager31, Frank Jaksch32, Georges Janssens30, Martin Borch Jensen33, Matt Kaeberlein34, Gerard Karsenty35, Peter de Keizer36, Brian Kennedy2,37,38, James L Kirkland39, Michael Kjaer40, Guido Kroemer41, Kai-Fu Lee42, Jean-Marc Lemaitre43, David Liaskos44, Valter D Longo45, Yu-Xuan Lu3, Michael R MacArthur46, Andrea B Maier38,47,48, Christina Manakanatas49, Sarah J Mitchell46, Alexey Moskalev50,51, Laura Niedernhofer52, Ivan Ozerov53, Linda Partridge3, Emmanuelle Passegué54, Michael A Petr1,55, James Peyer56, Dina Radenkovic57, Thomas A Rando58, Suresh Rattan59, Christian G Riedel60, Lenhard Rudolph18, Ruixue Ai61, Manuel Serrano62, Björn Schumacher14, David A Sinclair63, Ryan Smith64, Yousin Suh65, Pam Taub66, Alexandre Trapp25, Anne-Ulrike Trendelenburg67, Dario Riccardo Valenzano3,18, Kris Verburgh68, Eric Verdin2, Jan Vijg4, Rudi G J Westendorp69, Alessandra Zonari70, Daniela Bakula1, Alex Zhavoronkov53, Morten Scheibye-Knudsen1.   

Abstract

Aging is the single largest risk factor for most chronic diseases, and thus possesses large socioeconomic interest to continuously aging societies. Consequently, the field of aging research is expanding alongside a growing focus from the industry and investors in aging research. This year's 8th Annual Aging Research and Drug Discovery (ARDD) meeting was organized as a hybrid meeting from August 30th to September 3rd 2021 with more than 130 attendees participating on-site at the Ceremonial Hall at University of Copenhagen, Denmark, and 1800 engaging online. The conference comprised of presentations from 75 speakers focusing on new research in topics including mechanisms of aging and how these can be modulated as well as the use of AI and new standards of practices within aging research. This year, a longevity workshop was included to build stronger connections with the clinical community.

Entities:  

Keywords:  AI; aging; conference; drug discovery; longevity

Year:  2022        PMID: 35089871      PMCID: PMC8833115          DOI: 10.18632/aging.203859

Source DB:  PubMed          Journal:  Aging (Albany NY)        ISSN: 1945-4589            Impact factor:   5.682


  55 in total

1.  Reduced nicotinamide mononucleotide is a new and potent NAD+ precursor in mammalian cells and mice.

Authors:  Rubén Zapata-Pérez; Alessandra Tammaro; Bauke V Schomakers; Angelique M L Scantlebery; Simone Denis; Hyung L Elfrink; Judith Giroud-Gerbetant; Carles Cantó; Carmen López-Leonardo; Rebecca L McIntyre; Michel van Weeghel; Álvaro Sánchez-Ferrer; Riekelt H Houtkooper
Journal:  FASEB J       Date:  2021-04       Impact factor: 5.191

2.  AgRP Neurons Control Systemic Insulin Sensitivity via Myostatin Expression in Brown Adipose Tissue.

Authors:  Sophie M Steculorum; Johan Ruud; Ismene Karakasilioti; Heiko Backes; Linda Engström Ruud; Katharina Timper; Martin E Hess; Eva Tsaousidou; Jan Mauer; Merly C Vogt; Lars Paeger; Stephan Bremser; Andreas C Klein; Donald A Morgan; Peter Frommolt; Paul T Brinkkötter; Philipp Hammerschmidt; Thomas Benzing; Kamal Rahmouni; F Thomas Wunderlich; Peter Kloppenburg; Jens C Brüning
Journal:  Cell       Date:  2016-03-24       Impact factor: 41.582

3.  A high-fat diet and NAD(+) activate Sirt1 to rescue premature aging in cockayne syndrome.

Authors:  Morten Scheibye-Knudsen; Sarah J Mitchell; Evandro F Fang; Teruaki Iyama; Theresa Ward; James Wang; Christopher A Dunn; Nagendra Singh; Sebastian Veith; Md Mahdi Hasan-Olive; Aswin Mangerich; Mark A Wilson; Mark P Mattson; Linda H Bergersen; Victoria C Cogger; Alessandra Warren; David G Le Couteur; Ruin Moaddel; David M Wilson; Deborah L Croteau; Rafael de Cabo; Vilhelm A Bohr
Journal:  Cell Metab       Date:  2014-11-04       Impact factor: 27.287

Review 4.  Extending human healthspan and longevity: a symposium report.

Authors:  Loren M DeVito; Nir Barzilai; Ana Maria Cuervo; Laura J Niedernhofer; Sofiya Milman; Morgan Levine; Daniel Promislow; Luigi Ferrucci; George A Kuchel; Joan Mannick; Jamie Justice; Mitzi M Gonzales; James L Kirkland; Pinchas Cohen; Judith Campisi
Journal:  Ann N Y Acad Sci       Date:  2021-09-08       Impact factor: 6.499

Review 5.  Osteocalcin in the brain: from embryonic development to age-related decline in cognition.

Authors:  Arnaud Obri; Lori Khrimian; Gerard Karsenty; Franck Oury
Journal:  Nat Rev Endocrinol       Date:  2018-01-29       Impact factor: 43.330

6.  PhotoAgeClock: deep learning algorithms for development of non-invasive visual biomarkers of aging.

Authors:  Eugene Bobrov; Anastasia Georgievskaya; Konstantin Kiselev; Artem Sevastopolsky; Alex Zhavoronkov; Sergey Gurov; Konstantin Rudakov; Maria Del Pilar Bonilla Tobar; Sören Jaspers; Sven Clemann
Journal:  Aging (Albany NY)       Date:  2018-11-09       Impact factor: 5.682

7.  Senolytics improve physical function and increase lifespan in old age.

Authors:  Ming Xu; Tamar Pirtskhalava; Joshua N Farr; Bettina M Weigand; Allyson K Palmer; Megan M Weivoda; Christina L Inman; Mikolaj B Ogrodnik; Christine M Hachfeld; Daniel G Fraser; Jennifer L Onken; Kurt O Johnson; Grace C Verzosa; Larissa G P Langhi; Moritz Weigl; Nino Giorgadze; Nathan K LeBrasseur; Jordan D Miller; Diana Jurk; Ravinder J Singh; David B Allison; Keisuke Ejima; Gene B Hubbard; Yuji Ikeno; Hajrunisa Cubro; Vesna D Garovic; Xiaonan Hou; S John Weroha; Paul D Robbins; Laura J Niedernhofer; Sundeep Khosla; Tamara Tchkonia; James L Kirkland
Journal:  Nat Med       Date:  2018-07-09       Impact factor: 53.440

8.  PsychoAge and SubjAge: development of deep markers of psychological and subjective age using artificial intelligence.

Authors:  Alex Zhavoronkov; Kirill Kochetov; Peter Diamandis; Maria Mitina
Journal:  Aging (Albany NY)       Date:  2020-12-08       Impact factor: 5.682

9.  Isobacachalcone induces autophagy and improves the outcome of immunogenic chemotherapy.

Authors:  Qi Wu; Ai-Ling Tian; Sylvère Durand; Fanny Aprahamian; Nitharsshini Nirmalathasan; Wei Xie; Peng Liu; Liwei Zhao; Shuai Zhang; Hui Pan; Didac Carmona-Gutierrez; Frank Madeo; Yi Tu; Oliver Kepp; Guido Kroemer
Journal:  Cell Death Dis       Date:  2020-11-26       Impact factor: 8.469

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