Literature DB >> 350759

Regulation of immune response to SRBC: suppressor cell activity induced by soluble fraction of antigen.

M L Lukić, A Janezić, L Popesković.   

Abstract

Water soluble fraction (SF) of SRBC was obtained by hypotonic lysis and ultracentrifugation. SF was found to induce very weak SRBC-specific antibody response in mice. Pretreatment with SF accelerated direct PFC response to SRBC and accelerated and suppressed indirect PFC response. Spleen cells from mice treated with SF exhibited enhanced response to SRBC after transfer in irradiated recipients. The transfer of spleen cells from mice treated with SF to normal non-irradiated mice markedly suppressed the recipients' PFC responses to SRBC. The observed suppressive effect is interpreted as a consequence of suppressor cell activity.

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Year:  1978        PMID： 350759      PMCID： PMC1457200     

Source DB:  PubMed          Journal:  Immunology        ISSN： 0019-2805            Impact factor:   7.397


  33 in total

1.  Tolerance to heterologous erythrocytes.

Authors:  R Auerbach; J Roethle
Journal:  Science       Date:  1974-01-25       Impact factor: 47.728

2.  Editorial: Immune activation of B cells: evidence for 'one nonspecific triggering signal' not delivered by the Ig receptors.

Authors:  A Coutinho; G Möller
Journal:  Scand J Immunol       Date:  1974       Impact factor: 3.487

3.  Specific suppression of immune responses.

Authors:  D A Rowley; F W Fitch; F P Stuart; H Köhler; H Cosenza
Journal:  Science       Date:  1973-09-21       Impact factor: 47.728

4.  Strain differences in ease of tolerance induction to bovine gamma-globulin: dependence on macrophage function.

Authors:  M L Lukić; C Cowing; S Leskowitz
Journal:  J Immunol       Date:  1975-01       Impact factor: 5.422

5.  Influence of reticuloendothelial blockade on the induction of tolerance and immunity by polysaccharides.

Authors:  G Chaouat; J G Howard
Journal:  Immunology       Date:  1976-02       Impact factor: 7.397

6.  Studies on actively allergized cells. I. The cyto-dynamics and morphology of rosete-forming lymph node cells in mice and inhibition of rosette-formation with antibody to mouse immunoglobulins.

Authors:  I McConnell; A Munro; B W Gurner; R R Coombs
Journal:  Int Arch Allergy Appl Immunol       Date:  1969

7.  Hapten-induced paralysis. I. Evidence for the persistence of hapten-specific immunocompetent B lymphocytes in specifically paralyzed mice.

Authors:  E Gronowicz; A Coutinho; O Sjöberg
Journal:  Eur J Immunol       Date:  1974-03       Impact factor: 5.532

8.  Evidence for specific suppression in the maintenance of immunologic tolerance.

Authors:  D C Benjamin
Journal:  J Exp Med       Date:  1975-03-01       Impact factor: 14.307

9.  Induction of tolerance to sheep red blood cells.

Authors:  T H Anderson; J Roethle; R Auerbach
Journal:  J Exp Med       Date:  1972-12-01       Impact factor: 14.307

10.  Immunological tolerance to a hapten. I. Induction and maintenance of tolerance to trinitrophenyl with trinitrobenzene sulfonic acid.

Authors:  J M Fidler; E S Golub
Journal:  J Exp Med       Date:  1973-01-01       Impact factor: 14.307
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  1 in total

1.  Effect of chronic administration of morphine on primary immune response in mice.

Authors:  M Güngör; E Genç; H Sağduyu; L Eroğlu; H Koyuncuoğlu
Journal:  Experientia       Date:  1980-11-15
  1 in total

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