Literature DB >> 35072916

Conversion from dose length product to effective dose for the CT component of whole-body PET/CT.

Yusuke Inoue1, Yu Ohkubo2, Kazunori Nagahara3, Ayuka Uehara3, Makoto Takano3.   

Abstract

OBJECTIVE: For dose management of CT, the ratio of effective dose (ED) to dose length product (DLP) is often used to convert DLP to ED. We evaluated this ratio in the CT component of whole-body PET/CT performed under various imaging conditions to determine a practical method for ED estimation applicable to PET/CT.
METHODS: In total, 400 patients who underwent whole-body PET/CT were enrolled. The imaging conditions were variable in terms of the scanner model, setting of automatic exposure control (AEC) setting and arm positioning. The scan range was divided into six anatomical regions. DLP was calculated for each region, and multiplied by the conversion factor for the respective region to determine regional ED. The six regional EDs were summed together to determine ED by the regional DLP method (EDrDLP). Additionally, regional ED was assessed using CT-Expo, software dedicated to CT dose estimation, and the total of six regional EDs were defined as ED by the CT-Expo method (EDCT-Expo). EDrDLP/DLP and EDCT-Expo/DLP were calculated using DLP automatically provided by the scanner.
RESULTS: EDrDLP/DLP ranged from 0.0121 to 0.0128 mSv/mGy/cm with the arms up and from 0.0127 to 0.0134 mSv/mGy/cm with the arms down. Putting the arms down slightly increased EDrDLP/DLP, presumably due to an increased contribution of the chest and abdomen to total radiation exposure. The AEC setting and scanner model also influenced EDrDLP/DLP significantly but slightly. EDCT-Expo/DLP showed apparent scanner dependence, which appeared mainly attributable to differences in the constants used for DLP calculation between the scanner and CT-Expo.
CONCLUSION: Multiplication of scanner-derived DLP by a conversion factor of 0.013 mSv/mGy/cm provides acceptable ED estimates.
© 2022. The Author(s) under exclusive licence to The Japanese Society of Nuclear Medicine.

Entities:  

Keywords:  Dose length product; Effective dose; PET/CT; Radiation dose; Whole body

Mesh:

Year:  2022        PMID: 35072916     DOI: 10.1007/s12149-022-01720-0

Source DB:  PubMed          Journal:  Ann Nucl Med        ISSN: 0914-7187            Impact factor:   2.668


  2 in total

1.  Procedure guideline for tumor imaging with 18F-FDG PET/CT 1.0.

Authors:  Dominique Delbeke; R Edward Coleman; Milton J Guiberteau; Manuel L Brown; Henry D Royal; Barry A Siegel; David W Townsend; Lincoln L Berland; J Anthony Parker; Karl Hubner; Michael G Stabin; George Zubal; Marc Kachelriess; Valerie Cronin; Scott Holbrook
Journal:  J Nucl Med       Date:  2006-05       Impact factor: 10.057

2.  Effective dose estimation for oncological and neurological PET/CT procedures.

Authors:  Josep M Martí-Climent; Elena Prieto; Verónica Morán; Lidia Sancho; Macarena Rodríguez-Fraile; Javier Arbizu; María J García-Velloso; José A Richter
Journal:  EJNMMI Res       Date:  2017-04-24       Impact factor: 3.138

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.