Literature DB >> 350608

Effect of an LH-RH antagonist on reproductive status of immature female rats.

A Corbin.   

Abstract

Administration of the LH-RH antagonist, D-Phe2-D-Ala6-LH-RH (Wy-18, 185) to immature female rats from days 25--35 of age was without significant effect on day of vaginal opening (puberal onset), weights of the ovaries, uteri and anterior pituitary, and on ovarian histology on autopsy day 39.

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Year:  1978        PMID： 350608     DOI： 10.1007/bf01947344

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  6 in total

1.  Ihibition of the pre-ovulatory proestrous gonadotropin surge, ovulation and pregnancy with a peptide analogue of luteinizing hormone releasing hormone.

Authors:  A Corbin; C W Beattie
Journal:  Endocr Res Commun       Date:  1975

2.  Luteinizing hormone-releasing hormone. Antiovulatory activity of analogs substituted in positions 2 and 6.

Authors:  C W Beattie; A Corbin; T J Foell; V Garsky; W A McKinley; R W Rees; D Sarantakis; J P Yardley
Journal:  J Med Chem       Date:  1975-12       Impact factor: 7.446

3.  Antagonism of luteinizing hormone release and of ovulation by an analog of the luteinizing hormone-releasing hormone.

Authors:  J P Yardley; T J Foell; C W Beattie; N H Grant
Journal:  J Med Chem       Date:  1975-12       Impact factor: 7.446

4.  Anti-ovulatory/anti-pregnancy effects of (D-Phe2)-LRH analogs administered early in the rat estrous cycle.

Authors:  C W Beattie; A Corbin; T J Foell; V Garsky; R W Rees; J Yardley
Journal:  Contraception       Date:  1976-03       Impact factor: 3.375

5.  Comparison of the anti-LH/FSH-RH and anti-ovulatory activities of (D-Phe2, D-Leu6)-LH-RH and (D-Phe2, D-Ala6)-LH-RH.

Authors:  J A Vilchez-Martinez; D H Coy; E J Coy; A Arimura; A V Schally
Journal:  Endocr Res Commun       Date:  1976

6.  Effect of luteinizing hormone releasing hormone (LHRH) and an LHRH antagonist of hypothalamic and plasma LHRH of hypophysectomized rats.

Authors:  A Corbin; C W Beattie
Journal:  Endocrinology       Date:  1976-01       Impact factor: 4.736
  6 in total

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