Literature DB >> 35047371

Progress of clinical therapies for dry age-related macular degeneration.

Rhianna Rubner1, Kang V Li1, M Valeria Canto-Soler1.   

Abstract

Dry age-related macular degeneration (AMD) is a progressive blinding disease that currently affects millions of people worldwide with no successful treatment available. Significant research efforts are currently underway to develop therapies aimed at slowing the progression of this disease or, more notably, reversing it. Here the therapies which have reached clinical trial for treatment of dry AMD were reviewed. A thorough search of PubMed, Embase, and Clinicaltrials.gov has led to a comprehensive collection of the most recent strategies being evaluated. This review also endeavors to assess the status and future directions of therapeutics for this debilitating condition. International Journal of Ophthalmology Press.

Entities:  

Keywords:  age-related macular degeneration; drug therapy; dry age-related macular degeneration

Year:  2022        PMID： 35047371      PMCID： PMC8720345          DOI： 10.18240/ijo.2022.01.23

Source DB:  PubMed          Journal:  Int J Ophthalmol        ISSN： 2222-3959            Impact factor:   1.779


  35 in total

Review 1.  Complement factor D, a novel serine protease.

Authors:  J E Volanakis; S V Narayana
Journal:  Protein Sci       Date:  1996-04       Impact factor: 6.725

2.  Neuroprotection of retinal ganglion cells by brimonidine in rats with laser-induced chronic ocular hypertension.

Authors:  E WoldeMussie; G Ruiz; M Wijono; L A Wheeler
Journal:  Invest Ophthalmol Vis Sci       Date:  2001-11       Impact factor: 4.799

Review 3.  Retinal prostheses in degenerative retinal diseases.

Authors:  Tai-Chi Lin; Hua-Ming Chang; Chih-Chien Hsu; Kuo-Hsuan Hung; Yan-Ting Chen; Szu-Yu Chen; Shih-Jen Chen
Journal:  J Chin Med Assoc       Date:  2015-06-30       Impact factor: 2.743

4.  Autologous Induced Stem-Cell-Derived Retinal Cells for Macular Degeneration.

Authors:  Michiko Mandai; Akira Watanabe; Yasuo Kurimoto; Yasuhiko Hirami; Chikako Morinaga; Takashi Daimon; Masashi Fujihara; Hiroshi Akimaru; Noriko Sakai; Yumiko Shibata; Motoki Terada; Yui Nomiya; Shigeki Tanishima; Masahiro Nakamura; Hiroyuki Kamao; Sunao Sugita; Akishi Onishi; Tomoko Ito; Kanako Fujita; Shin Kawamata; Masahiro J Go; Chikara Shinohara; Ken-Ichiro Hata; Masanori Sawada; Midori Yamamoto; Sachiko Ohta; Yasuo Ohara; Kenichi Yoshida; Junko Kuwahara; Yuko Kitano; Naoki Amano; Masafumi Umekage; Fumiyo Kitaoka; Azusa Tanaka; Chihiro Okada; Naoko Takasu; Seishi Ogawa; Shinya Yamanaka; Masayo Takahashi
Journal:  N Engl J Med       Date:  2017-03-16       Impact factor: 91.245

5.  Long-Term Results from an Epiretinal Prosthesis to Restore Sight to the Blind.

Authors:  Allen C Ho; Mark S Humayun; Jessy D Dorn; Lyndon da Cruz; Gislin Dagnelie; James Handa; Pierre-Olivier Barale; José-Alain Sahel; Paulo E Stanga; Farhad Hafezi; Avinoam B Safran; Joel Salzmann; Arturo Santos; David Birch; Rand Spencer; Artur V Cideciyan; Eugene de Juan; Jacque L Duncan; Dean Eliott; Amani Fawzi; Lisa C Olmos de Koo; Gary C Brown; Julia A Haller; Carl D Regillo; Lucian V Del Priore; Aries Arditi; Duane R Geruschat; Robert J Greenberg
Journal:  Ophthalmology       Date:  2015-07-08       Impact factor: 12.079

Review 6.  Mechanisms of age-related macular degeneration.

Authors:  Jayakrishna Ambati; Benjamin J Fowler
Journal:  Neuron       Date:  2012-07-12       Impact factor: 17.173

7.  Emixustat Hydrochloride for Geographic Atrophy Secondary to Age-Related Macular Degeneration: A Randomized Clinical Trial.

Authors:  Philip J Rosenfeld; Pravin U Dugel; Frank G Holz; Jeffrey S Heier; Joel A Pearlman; Roger L Novack; Karl G Csaky; John M Koester; Jeffrey K Gregory; Ryo Kubota
Journal:  Ophthalmology       Date:  2018-04-30       Impact factor: 12.079

8.  Visual Cycle Modulation as an Approach toward Preservation of Retinal Integrity.

Authors:  Claes Bavik; Susan Hayes Henry; Yan Zhang; Kyoko Mitts; Tim McGinn; Ewa Budzynski; Andriy Pashko; Kuo Lee Lieu; Sheng Zhong; Bruce Blumberg; Vladimir Kuksa; Mark Orme; Ian Scott; Ahmad Fawzi; Ryo Kubota
Journal:  PLoS One       Date:  2015-05-13       Impact factor: 3.240

9.  Stem Cell Ophthalmology Treatment Study (SCOTS): Bone Marrow-Derived Stem Cells in the Treatment of Age-Related Macular Degeneration.

Authors:  Jeffrey N Weiss; Steven Levy
Journal:  Medicines (Basel)       Date:  2020-03-28
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.