Literature DB >> 35035325

The Role Of Comorbidities On Outcome Prediction In Acute Burn Patients.

C Brandão1, R Meireles1, I Brito1, S Ramos1, L Cabral1.   

Abstract

Burn trauma is a leading cause of mortality and morbidity. None of the currently available formulas for mortality prediction take into account the impact of comorbidities on burn patients' outcome. In this study, we evaluate the impact of comorbidities on in-hospital mortality and prolonged length of hospital stay (≥30 days). A retrospective analysis of burn patients' medical records, over a 5-year period, was undertaken. A total of 677 patients were included. The mortality rate was 6.5%. Deceased patients and survivors with length of hospital stay (LOS) of 30 or more days were significantly older, had larger %TBSA burned, were more likely to have inhalation injury and comorbidities, and had higher Charlson Comorbidity Index (CCI) scores. On the multivariate logistic regression models, age, %TBSA burned, CCI score and the presence of inhalation injury were independently associated with mortality and prolonged LOS. In conclusion, the authors suggest that the inclusion of comorbidities should be considered on burn admission scores in an attempt to better predict burn mortality.
Copyright © 2021 Euro-Mediterranean Council for Burns and Fire Disasters.

Entities:  

Keywords:  burn; comorbidities; mortality

Year:  2021        PMID: 35035325      PMCID: PMC8717902     

Source DB:  PubMed          Journal:  Ann Burns Fire Disasters        ISSN: 1592-9558


  14 in total

1.  Prediction of morbidity and mortality on admission to a burn unit.

Authors:  Sagit Meshulam-Derazon; Shira Nachumovsky; Dean Ad-El; Jaqueline Sulkes; Daniel J Hauben
Journal:  Plast Reconstr Surg       Date:  2006-07       Impact factor: 4.730

2.  Not all patients meet the 1day per percent burn rule: A simple method for predicting hospital length of stay in patients with burn.

Authors:  Sandra L Taylor; Soman Sen; David G Greenhalgh; MaryBeth Lawless; Terese Curri; Tina L Palmieri
Journal:  Burns       Date:  2016-12-29       Impact factor: 2.744

3.  Assessment of mortality prediction models in a Ghanaian burn population.

Authors:  N Brusselaers; P Agbenorku; P E Hoyte-Williams
Journal:  Burns       Date:  2012-11-10       Impact factor: 2.744

4.  Predicting survival in an elderly burn patient population.

Authors:  L A Wibbenmeyer; M J Amelon; L J Morgan; B K Robinson; P X Chang; R Lewis; G P Kealey
Journal:  Burns       Date:  2001-09       Impact factor: 2.744

5.  Frailty score on admission predicts outcomes in elderly burn injury.

Authors:  Kathleen S Romanowski; Alura Barsun; Tina L Pamlieri; David G Greenhalgh; Soman Sen
Journal:  J Burn Care Res       Date:  2015 Jan-Feb       Impact factor: 1.845

6.  The measured effect magnitude of co-morbidities on burn injury mortality.

Authors:  Laquanda Knowlin; Lindsay Stanford; Danier Moore; Bruce Cairns; Anthony Charles
Journal:  Burns       Date:  2016-09-01       Impact factor: 2.744

Review 7.  A three decade analysis of factors affecting burn mortality in the elderly.

Authors:  G T Lionelli; E J Pickus; O K Beckum; R L Decoursey; R A Korentager
Journal:  Burns       Date:  2005-11-02       Impact factor: 2.744

8.  The APACHE III prognostic system. Risk prediction of hospital mortality for critically ill hospitalized adults.

Authors:  W A Knaus; D P Wagner; E A Draper; J E Zimmerman; M Bergner; P G Bastos; C A Sirio; D J Murphy; T Lotring; A Damiano
Journal:  Chest       Date:  1991-12       Impact factor: 9.410

9.  The effects of preexisting medical comorbidities on mortality and length of hospital stay in acute burn injury: evidence from a national sample of 31,338 adult patients.

Authors:  Brett D Thombs; Vijay A Singh; Jill Halonen; Alfa Diallo; Stephen M Milner
Journal:  Ann Surg       Date:  2007-04       Impact factor: 12.969

10.  Survival analysis and mortality predictors of hospitalized severe burn victims in a Malaysian burns intensive care unit.

Authors:  Henry Tan Chor Lip; Jih Huei Tan; Mathew Thomas; Farrah-Hani Imran; Tuan Nur' Azmah Tuan Mat
Journal:  Burns Trauma       Date:  2019-01-28
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  2 in total

1.  Characterization of the Basal and mTOR-Dependent Acute Pulmonary and Systemic Immune Response in a Murine Model of Combined Burn and Inhalation Injury.

Authors:  Hannah R Hall; Cressida Mahung; Julia L M Dunn; Laurel M Kartchner; Roland F Seim; Bruce A Cairns; Shannon M Wallet; Robert Maile
Journal:  Int J Mol Sci       Date:  2022-08-07       Impact factor: 6.208

2.  Multiplexed Human Gene Expression Analysis Reveals a Central Role of the TLR/mTOR/PPARγ and NFkB Axes in Burn and Inhalation Injury-Induced Changes in Systemic Immunometabolism and Long-Term Patient Outcomes.

Authors:  Cressida Mahung; Shannon M Wallet; Jordan E Jacobs; Laura Y Zhou; Haibo Zhou; Bruce A Cairns; Robert Maile
Journal:  Int J Mol Sci       Date:  2022-08-20       Impact factor: 6.208

  2 in total

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