Literature DB >> 35032547

Senolytic drugs: Beyond the promise and the hype.

Diana Jurk1, João F Passos2.   

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Year:  2022        PMID: 35032547      PMCID: PMC9242582          DOI: 10.1016/j.mad.2022.111631

Source DB:  PubMed          Journal:  Mech Ageing Dev        ISSN: 0047-6374            Impact factor:   5.498


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  12 in total

Review 1.  Cellular Senescence: Defining a Path Forward.

Authors:  Vassilis Gorgoulis; Peter D Adams; Andrea Alimonti; Dorothy C Bennett; Oliver Bischof; Cleo Bishop; Judith Campisi; Manuel Collado; Konstantinos Evangelou; Gerardo Ferbeyre; Jesús Gil; Eiji Hara; Valery Krizhanovsky; Diana Jurk; Andrea B Maier; Masashi Narita; Laura Niedernhofer; João F Passos; Paul D Robbins; Clemens A Schmitt; John Sedivy; Konstantinos Vougas; Thomas von Zglinicki; Daohong Zhou; Manuel Serrano; Marco Demaria
Journal:  Cell       Date:  2019-10-31       Impact factor: 41.582

Review 2.  Activatable senoprobes and senolytics: Novel strategies to detect and target senescent cells.

Authors:  Samir Morsli; Gary J Doherty; Daniel Muñoz-Espín
Journal:  Mech Ageing Dev       Date:  2022-01-03       Impact factor: 5.432

Review 3.  Skeletal muscle aging, cellular senescence, and senotherapeutics: Current knowledge and future directions.

Authors:  Davis A Englund; Xu Zhang; Zaira Aversa; Nathan K LeBrasseur
Journal:  Mech Ageing Dev       Date:  2021-11-03       Impact factor: 5.432

Review 4.  A guide to senolytic intervention in neurodegenerative disease.

Authors:  Suckwon Lee; Ellen Y Wang; Alexandra B Steinberg; Chaska C Walton; Shankar J Chinta; Julie K Andersen
Journal:  Mech Ageing Dev       Date:  2021-10-08       Impact factor: 5.432

Review 5.  Recent advances in the discovery of senolytics.

Authors:  Lei Zhang; Louise E Pitcher; Vaishali Prahalad; Laura J Niedernhofer; Paul D Robbins
Journal:  Mech Ageing Dev       Date:  2021-10-14       Impact factor: 5.432

Review 6.  Promises and challenges of senolytics in skin regeneration, pathology and ageing.

Authors:  Vera Pils; Nadja Ring; Karla Valdivieso; Ingo Lämmermann; Florian Gruber; Markus Schosserer; Johannnes Grillari; Mikolaj Ogrodnik
Journal:  Mech Ageing Dev       Date:  2021-10-19       Impact factor: 5.498

Review 7.  A geroscience motivated approach to treat Alzheimer's disease: Senolytics move to clinical trials.

Authors:  Mitzi M Gonzales; Sudarshan Krishnamurthy; Valentina Garbarino; Ali S Daeihagh; Gregory J Gillispie; Gagan Deep; Suzanne Craft; Miranda E Orr
Journal:  Mech Ageing Dev       Date:  2021-10-21       Impact factor: 5.498

8.  Senolytic Drugs: Reducing Senescent Cell Viability to Extend Health Span.

Authors:  Paul D Robbins; Diana Jurk; Sundeep Khosla; James L Kirkland; Nathan K LeBrasseur; Jordan D Miller; João F Passos; Robert J Pignolo; Tamar Tchkonia; Laura J Niedernhofer
Journal:  Annu Rev Pharmacol Toxicol       Date:  2020-09-30       Impact factor: 13.820

Review 9.  The potential of Senolytics in transplantation.

Authors:  Tomohisa Matsunaga; Jasper Iske; Andreas Schroeter; Haruhito Azuma; Hao Zhou; Stefan G Tullius
Journal:  Mech Ageing Dev       Date:  2021-10-01       Impact factor: 5.432

Review 10.  Strategies for late phase preclinical and early clinical trials of senolytics.

Authors:  Erin O Wissler Gerdes; Avanish Misra; Jair Machado Espindola Netto; Tamar Tchkonia; James L Kirkland
Journal:  Mech Ageing Dev       Date:  2021-10-23       Impact factor: 5.432

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  2 in total

Review 1.  Mechanisms and consequences of endothelial cell senescence.

Authors:  Samuel I Bloom; Md Torikul Islam; Lisa A Lesniewski; Anthony J Donato
Journal:  Nat Rev Cardiol       Date:  2022-07-19       Impact factor: 49.421

Review 2.  Aging of mesenchymal stem cell: machinery, markers, and strategies of fighting.

Authors:  Mahmoud Al-Azab; Mohammed Safi; Elina Idiiatullina; Fadhl Al-Shaebi; Mohamed Y Zaky
Journal:  Cell Mol Biol Lett       Date:  2022-08-19       Impact factor: 8.702

  2 in total

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