Agnik Haldar1, Ajay Kumar Singh2. 1. Department of Bioinfomatics, Center for Biological Sciences (Bioinformatics), Central University of South Bihar, Panchanpur Road, Fathehpur, Tekari, Gaya, 824236, Bihar, India. 2. Department of Bioinfomatics, Center for Biological Sciences (Bioinformatics), Central University of South Bihar, Panchanpur Road, Fathehpur, Tekari, Gaya, 824236, Bihar, India. ajaysingh@cusb.ac.in.
Abstract
BACKGROUND: Oral cancer is considered one of the most prevalent cancers in India. This is mainly because India suffers from high usage of tobacco, which is one of the main causative agents of oral cancer, and lacks proper health and sexual hygiene in rural areas. DISCUSSION: Non-coding RNAs are reported to be involved in the various mechanism and causality of cancer. Numerous reports have identified viable prospects connecting non-coding RNA (ncRNA) with cancer. Specific ncRNAs like long non-coding RNA or lncRNAs are recently being prioritized as potential associations in the cause of cancer. CONCLUSION: This review aims at presenting a concise perspective on the basics and the recent advancements of the lncRNA research pertaining specifically to oral cancer, its recurrence, and the future possibilities of knowledge it might possess.
BACKGROUND: Oral cancer is considered one of the most prevalent cancers in India. This is mainly because India suffers from high usage of tobacco, which is one of the main causative agents of oral cancer, and lacks proper health and sexual hygiene in rural areas. DISCUSSION: Non-coding RNAs are reported to be involved in the various mechanism and causality of cancer. Numerous reports have identified viable prospects connecting non-coding RNA (ncRNA) with cancer. Specific ncRNAs like long non-coding RNA or lncRNAs are recently being prioritized as potential associations in the cause of cancer. CONCLUSION: This review aims at presenting a concise perspective on the basics and the recent advancements of the lncRNA research pertaining specifically to oral cancer, its recurrence, and the future possibilities of knowledge it might possess.
Authors: Mohammed Arif; Bhusainahalli M Vedamurthy; Ramesh Choudhari; Yogesh B Ostwal; Kempegowda Mantelingu; Gopinath S Kodaganur; Tapas K Kundu Journal: Chem Biol Date: 2010-08-27