| Literature DB >> 35015088 |
Karl Werdan1,2, Markus Wolfgang Ferrari3, Roland Prondzinsky4, Martin Ruß5.
Abstract
Cardiogenic shock as a complication of myocardial infarction (5-10%) increases the mortality of uncomplicated myocardial infarction from less than 10% to 40%. This is due to the development of multiple organ dysfunction syndrome triggered by the extensive shock-induced impairment of organ perfusion. Therefore, guideline-based treatment should not only be restricted to reopening of the occluded coronary artery and management of complications of the infarction: important for survival are also guideline-driven optimization of organ perfusion by inotropic and vasoactive substances and, with well-defined indications, by temporary mechanical circulatory support but not by intra-aortic counterpulsation. Equally important, however, are shock-specific intensive care measures to prevent or attenuate organ dysfunction, such as lung protective ventilation in cases where ventilation is obligatory.Entities:
Keywords: Guidelines; Intra-aortic balloon counterpulsation; Multiple organ failure; Percutaneous coronary intervention; Temporary mechanical support
Mesh:
Year: 2022 PMID: 35015088 DOI: 10.1007/s00059-021-05088-1
Source DB: PubMed Journal: Herz ISSN: 0340-9937 Impact factor: 1.443