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Literature DB >> 3500814

Increased lymphokine activated killer (LAK) activity in the regional lymph nodes of mice following immunization with contact sensitizing agents.

Abstract

The regional lymph nodes of mice show increased IL-2 activated killer (LAK) activity following immunization with the contact sensitizing agents, 'oxazolone' and picryl chloride. This is best elicited with 500 mu/ml human recombinant IL-2 and can be demonstrated with both YAC-1 and K562 targets. There is also a lesser increase in NK activity.

Entities: Chemical Gene Species

Mesh：

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Year: 1987 PMID： 3500814 PMCID： PMC1542224

Source DB: PubMed Journal: Clin Exp Immunol ISSN： 0009-9104 Impact factor: 4.330

13 in total

1. Contact sensitivity in the mouse. X. Non-specific cytotoxicity of T blasts in the draining lymph nodes.

Authors: G L Asherson; J Ferluga
Journal: Immunology Date: 1973-09 Impact factor: 7.397

2. Topical immunotherapy of basal cell carcinomas with dinitrochlorobenzene.

Authors: W R Levis; K H Kraemer; W G Klingler; G L Peck; W D Terry
Journal: Cancer Res Date: 1973-11 Impact factor: 12.701

Review 3. Management of mycosis fungoides--current status and future prospects.

Authors: J A Levi; P H Wiernik
Journal: Medicine (Baltimore) Date: 1975-01 Impact factor: 1.889

4. Immunogenic cells in the regional lymph nodes after painting with the contact sensitizers picryl chloride and oxazolone: evidence for the presence of IgM antibody on their surface.

Authors: G L Asherson; V Colizzi; M C Watkins
Journal: Immunology Date: 1983-03 Impact factor: 7.397

Review 5. Suppressor cells and the handling of antigen.

Authors: G L Asherson; M Zembala; W R Thomas; M A Perera
Journal: Immunol Rev Date: 1980 Impact factor: 12.988

6. T-cell depletion of allogeneic bone marrow prevents acceleration of graft-versus-host disease induced by exogenous interleukin 2.

Authors: M Malkovský; M K Brenner; R Hunt; S Rastan; C Doré; S Brown; M E North; G L Asherson; H G Prentice; P B Medawar
Journal: Cell Immunol Date: 1986-12 Impact factor: 4.868

7. Antitumor efficacy of lymphokine-activated killer cells and recombinant interleukin-2 in vivo: survival benefit and mechanisms of tumor escape in mice undergoing immunotherapy.

Authors: J J Mulé; S E Ettinghausen; P J Spiess; S Shu; S A Rosenberg
Journal: Cancer Res Date: 1986-02 Impact factor: 12.701

Increased lymphokine activated killer (LAK) activity in the regional lymph nodes of mice following immunization with contact sensitizing agents.

1. Contact sensitivity in the mouse. X. Non-specific cytotoxicity of T blasts in the draining lymph nodes.

2. Topical immunotherapy of basal cell carcinomas with dinitrochlorobenzene.

Review 3. Management of mycosis fungoides--current status and future prospects.

4. Immunogenic cells in the regional lymph nodes after painting with the contact sensitizers picryl chloride and oxazolone: evidence for the presence of IgM antibody on their surface.

Review 5. Suppressor cells and the handling of antigen.

6. T-cell depletion of allogeneic bone marrow prevents acceleration of graft-versus-host disease induced by exogenous interleukin 2.

7. Antitumor efficacy of lymphokine-activated killer cells and recombinant interleukin-2 in vivo: survival benefit and mechanisms of tumor escape in mice undergoing immunotherapy.

8. Acquired immunological tolerance of foreign cells is impaired by recombinant interleukin 2 or vitamin A acetate.

9. Dendritic cells that have interacted with antigen are targets for natural killer cells.

10. The activity of natural cytotoxic cells is augmented by interleukin 2 and interleukin 3.

Review 1. The interleukins in acquired disease.