Literature DB >> 35005783

To the bones: mapping the skeletal LEPR+ pool to component cell types.

Jun Sun1, Matthew B Greenblatt1,2.   

Abstract

Leptin receptor-positive skeletal progenitors constitute an essential cell population in the bone, yet their heterogeneity remains incompletely understood. In this issue, Mo et al (2021) report a single-cell RNA sequencing resource that deconvolutes the pool of LEPR+ skeletal cells under homeostatic and various pathologic conditions, uncovering context-dependent contributions to diverse cell types and functions.
© 2022 The Authors.

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Year:  2022        PMID： 35005783      PMCID： PMC8844985          DOI： 10.15252/embj.2021110343

Source DB:  PubMed          Journal:  EMBO J        ISSN： 0261-4189            Impact factor:   11.598


  13 in total

1.  The essential functions of adipo-osteogenic progenitors as the hematopoietic stem and progenitor cell niche.

Authors:  Yoshiki Omatsu; Tatsuki Sugiyama; Hiroshi Kohara; Gen Kondoh; Nobutaka Fujii; Kenji Kohno; Takashi Nagasawa
Journal:  Immunity       Date:  2010-09-24       Impact factor: 31.745

2.  To the bones: mapping the skeletal LEPR+ pool to component cell types.

Authors:  Jun Sun; Matthew B Greenblatt
Journal:  EMBO J       Date:  2022-01-10       Impact factor: 11.598

3.  Tracing the skeletal progenitor transition during postnatal bone formation.

Authors:  Hui Sophie Shu; Yiming Liam Liu; Xinyu Thomas Tang; Xinyi Shirley Zhang; Bin Zhou; Weiguo Zou; Bo O Zhou
Journal:  Cell Stem Cell       Date:  2021-09-08       Impact factor: 24.633

4.  Leptin-receptor-expressing mesenchymal stromal cells represent the main source of bone formed by adult bone marrow.

Authors:  Bo O Zhou; Rui Yue; Malea M Murphy; James G Peyer; Sean J Morrison
Journal:  Cell Stem Cell       Date:  2014-06-19       Impact factor: 24.633

5.  Single-cell transcriptomics of LepR-positive skeletal cells reveals heterogeneous stress-dependent stem and progenitor pools.

Authors:  Chunyang Mo; Jingxin Guo; Jiachen Qin; Xiaoying Zhang; Yuxi Sun; Hanjing Wei; Dandan Cao; Yiying Zhang; Chengchen Zhao; Yanhong Xiong; Yong Zhang; Yao Sun; Li Shen; Rui Yue
Journal:  EMBO J       Date:  2021-12-27       Impact factor: 11.598

6.  Stem cell niche-specific Ebf3 maintains the bone marrow cavity.

Authors:  Masanari Seike; Yoshiki Omatsu; Hitomi Watanabe; Gen Kondoh; Takashi Nagasawa
Journal:  Genes Dev       Date:  2018-03-21       Impact factor: 11.361

7.  A mechanosensitive peri-arteriolar niche for osteogenesis and lymphopoiesis.

Authors:  Bo Shen; Alpaslan Tasdogan; Jessalyn M Ubellacker; Jingzhu Zhang; Elena D Nosyreva; Liming Du; Malea M Murphy; Shuiqing Hu; Yating Yi; Nergis Kara; Xin Liu; Shay Guela; Yuemeng Jia; Vijayashree Ramesh; Claire Embree; Evann C Mitchell; Yunduo C Zhao; Lining A Ju; Zhao Hu; Genevieve M Crane; Zhiyu Zhao; Ruhma Syeda; Sean J Morrison
Journal:  Nature       Date:  2021-02-24       Impact factor: 49.962

8.  Discovery of a periosteal stem cell mediating intramembranous bone formation.

Authors:  Shawon Debnath; Alisha R Yallowitz; Jason McCormick; Sarfaraz Lalani; Tuo Zhang; Ren Xu; Na Li; Yifang Liu; Yeon Suk Yang; Mark Eiseman; Jae-Hyuck Shim; Meera Hameed; John H Healey; Mathias P Bostrom; Dan Avi Landau; Matthew B Greenblatt
Journal:  Nature       Date:  2018-09-24       Impact factor: 49.962

9.  A Wnt-mediated transformation of the bone marrow stromal cell identity orchestrates skeletal regeneration.

Authors:  Yuki Matsushita; Mizuki Nagata; Kenneth M Kozloff; Joshua D Welch; Koji Mizuhashi; Nicha Tokavanich; Shawn A Hallett; Daniel C Link; Takashi Nagasawa; Wanida Ono; Noriaki Ono
Journal:  Nat Commun       Date:  2020-01-16       Impact factor: 14.919

10.  Single cell transcriptomics identifies a unique adipose lineage cell population that regulates bone marrow environment.

Authors:  Leilei Zhong; Lutian Yao; Robert J Tower; Yulong Wei; Zhen Miao; Jihwan Park; Rojesh Shrestha; Luqiang Wang; Wei Yu; Nicholas Holdreith; Xiaobin Huang; Yejia Zhang; Wei Tong; Yanqing Gong; Jaimo Ahn; Katalin Susztak; Nathanial Dyment; Mingyao Li; Fanxin Long; Chider Chen; Patrick Seale; Ling Qin
Journal:  Elife       Date:  2020-04-14       Impact factor: 8.713
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  1 in total

1.  To the bones: mapping the skeletal LEPR+ pool to component cell types.

Authors:  Jun Sun; Matthew B Greenblatt
Journal:  EMBO J       Date:  2022-01-10       Impact factor: 11.598
  1 in total

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