Literature DB >> 35000244

Epidemiological evaluation of the outcomes of initial root canal therapy in permanent teeth of a publicly insured paediatric population.

Lorel E Burns1, Kelly Terlizzi2, Claudia Solis-Roman2, Yinxiang Wu3, Asgeir Sigurdsson1, Heather T Gold3.   

Abstract

BACKGROUND: Previously published epidemiological outcome studies of nonsurgical root canal therapy (NSRCT) in the United States utilize data only from a single, private dental insurer for adult populations. AIM: This study aimed to investigate the outcomes of initial NSRCT, performed on permanent teeth, in a publicly insured paediatric population.
DESIGN: New York State Medicaid administrative claims were used to follow 77 741 endodontic procedures in 51 545 patients aged 6-18, from the time of initial NSRCT until the occurrence of an untoward event (retreatment, apicoectomy, and extraction). The initial treatment and untoward events were identified by Current Dental Terminology codes. The Kaplan-Meier survival estimates were calculated at 1, 3, and 5 years. Hazard ratios for time to permanent restoration and restoration type were calculated using the Cox proportional hazards model.
RESULTS: The median follow-up time was 44 months [range: 12-158 months]. Procedural, NSRCT, survival was 98% at 1 year, 93% at 3 years, and 88% at 5 years. Extraction was the most common untoward event. Teeth permanently restored with cuspal coverage had the most favorable treatment outcomes.
CONCLUSIONS: Overall, 89% of teeth were retained and remained functional over a minimum follow-up time of 5 years. These results elucidate the expected outcomes of NSRCT in permanent teeth for paediatric patients with public-payer dental benefits.
© 2022 The Authors. International Journal of Paediatric Dentistry published by BSPD, IAPD and John Wiley & Sons Ltd.

Entities:  

Keywords:  endodontics; medicaid; paediatric dentistry; root canal therapy; survival analysis; treatment outcomes

Mesh:

Year:  2022        PMID: 35000244      PMCID: PMC9272438          DOI: 10.1111/ipd.12953

Source DB:  PubMed          Journal:  Int J Paediatr Dent        ISSN: 0960-7439            Impact factor:   3.264


INTRODUCTION

The success of endodontic procedures, including nonsurgical root canal therapy (NSRCT), is of interest to dentists, patients, and third-party payers. Typically, the outcomes of endodontic procedures are evaluated through the presence of clinical signs and symptoms, along with radiographic interpretation. Reported success rates based on these criteria have ranged from 31% to 98%.[1,2] The outcomes of initial NSRCT also have been evaluated using epidemiological methods,[3-7] with survival rates of 94% and higher in studies based in the United States.[3,4,6,7] Epidemiological or health services research methods that leverage the use of administrative claims data allow for the simultaneous study of very large cohorts and multiple variables potentially associated with treatment outcomes.[8] Variables shown to be associated with the success of NSRCT include time to the placement of permanent restoration and type of permanent restoration.[3,4,7,9,10] Both clinical- and population-level analyses of the outcomes of endodontic treatment are important to dental practitioners and oral health advocates alike, as findings from these studies can be used to inform clinical recommendations and policy. Dental coverage and dental care utilization by children (age 0–18) in the United States are at their highest-ever levels, since tracking began in 1999.[11-13] This increase in dental care utilization correlates with expansions in dental coverage through the Children's Health Insurance Program (CHIP) and the passage of the Affordable Care Act (ACA).[14] As of 2015, 90% of children in the United States had dental coverage, with 39% overall covered by public insurers (Medicaid/CHIP).[15] Currently, Medicaid provides dental coverage for income-eligible children up to the age of 21 and “at a minimum, dental services include relief of pain and infections, restoration of teeth, and maintenance of dental health.”[16] CHIP covers income-eligible children up to the age of 19 or 21, depending on the state, and provides dental services “necessary to prevent disease and promote oral health, restore oral structure to health and functions, and treat emergency functions.”[17] These definitions of covered services do not specify procedure codes, leaving this decision largely up to individual states. Children experiencing dental pain and infection that require root canal therapy in permanent teeth may present with unique root canal anatomy[18,19] and behavioral considerations[20,21] compared with adults. These differences often require distinct considerations and expertise, such as the ability to manage the behavior of children and adolescents[22] and the required proficiency to perform the technical aspects of endodontic treatment. There is currently a dearth of literature assessing the outcomes of root canal therapy performed on permanent teeth in paediatric populations. Previously published epidemiological outcome studies of root canal therapy in the United States utilize data from a single, private dental insurer focused on adult populations. The adult-focused epidemiological literature reports tooth survival rates to be above 90% five years after the initial root canal therapy.[3,4,6,7] These findings may not be applicable to the paediatric population. Motivated by the gaps in both the endodontic and paediatric dental literature and the increasingly large population of children with a public-payer dental insurance in the United States, the purpose of this study was to retrospectively investigate the survival of initial NSRCT performed on permanent teeth in a publicly insured paediatric population by using long-term, large-scale claims data.

MATERIALS AND METHODS

The data for this study are the electronic insurance claims records and enrollment database of the New York State Medicaid program. Limiting the search to enrollees aged 6–18 with at least one year of continuous enrollment, the database yielded 2 027 196 individuals with patient encounters that occurred between January 1, 2006, and December 31, 2018. Of the total individual enrollees, 51 545 had initial NSRCTs in the permanent dentition, and 77 741 relevant procedures/teeth were available for analysis. Codes on Dental Procedures (CDTs) were used to identify the endodontic therapy procedures (initial NSRCT) for analysis (D3310, D3320, and D3330). Further, CDTs were used to identify the placement of a permanent restoration after endodontic treatment and/or the incidence of an untoward event. Relevant permanent restorations (D2000-D2999) were categorized as buildups, amalgam, composite, or cuspal coverage. In cases where multiple restoration types were placed (eg, buildup followed by cuspal coverage), priority categorization was given to cuspal coverage. Untoward events were defined as nonsurgical retreatment (D3346, D3347, and D3348), apicoectomy (D3410, D3421, and D3425), or extraction (D7140 and D7210), and these indicated the failure of initial NSRCT. Initial NSRCTs were considered to be successful until the occurrence of an untoward event or censored at an identified lapse in the patient's enrollment status. The following information was collected for each initial NSRCT procedure: patient identification number, tooth number, date of initial NSRCT, patient age, patient gender, race or ethnicity, zip code, date of patient disenrollment in Medicaid, date of final restoration, type of final restoration, type of untoward event (up to the third), and date(s) of the untoward event(s). Zip codes were used to identify areas of “high poverty,” rural status, and dental health provider shortage areas (DHPSAs); poverty and rural status were merged using data from the 2008-2012 American Community Survey of the 2012 US Census.[23] Enrollees who resided in a zip code where more than 20% of the population lived below the federal poverty level (FPL) were classified as “high poverty.”[23] Rural areas were defined according to the Federal Office of Rural Health Policy.[24] For the purposes of this study, patients were classified as living in a DHPSA if their census tract, county, or county subdivision was deemed a geographic DHPSA at any point within our study period.[25] The Kaplan–Meier survival estimates were calculated for 1-, 3-, and 5 years outcomes of NSRCTs, with subset analyses stratified by tooth type, time until restoration, and restoration types. The data allowed for up to 12 years of follow-up after the completion of initial NSRCT. To account for the effects of patient age, tooth type, time until restoration, and restoration type, adjusted hazard ratios (aHRs) were estimated by fitting a multivariable Cox proportional hazards model on the subsample where all treated teeth had permanent restoration placed (N = 63 128). A sensitivity analysis was conducted to evaluate the potential bias resulting from censored enrollees on the survival estimates and aHR. The use of robust standard errors accounted for potential dependence between teeth within an individual. Data analysis was completed using SAS 9.4 (SAS Institute Inc, Cary, NC) software and R 4.0 (R Core Team, Vienna, Austria). This study was approved by New York University School of Medicine's Institutional Review Board (i19-01436), under the expedited status (category 5).

RESULTS

A total of 51 545 patients and 77 741 procedures were evaluated. Of the 51 545 patients, 44.1% were male and 55.9% were female. Over half (53.3%) of those included in the study resided in a zip code area where more than 20% of the people lived below the federal poverty level. Rural–urban indicators revealed that 7.0% lived in rural areas. Patients were classified by the following race/ethnicities: White/Caucasian (31.6%); Hispanic/Latino (23.3%); Black/African American (17.8%); Asian (11.1%); American Indian/Alaska Native (1.2%); or Native Hawaiian/Pacific Islander (0.3%). Race/ethnicity data were unknown/missing for 14.6% of patients. The mean number of initial NSRCTs per patient in this population was 1.51 with a standard deviation of 1.01 [median: 1; IQR: 1–2; range: 1–18]. The median patient age was 15 years [IQR: 13–16]. Patients aged 6–9 made up 4.0% of cases, those aged 10–12, 19.5%; the ones aged 13–15, 38.7%; and the ones aged 16–18, 37.9% of cases (Table 1). As patient age increased, there was a reduced risk of failure (Figure 1). Molars (lower first molars) were the most frequently treated tooth type (Table 1).
TABLE 1

Description of study cohort (A. tooth level; B. patient level)

A
Patient sample (n)51 545
Age category (%)
 6–92065 (4.0)
 10–1210 039 (19.5)
 13–1519 928 (38.7)
 16–1819 513 (37.9)
Age (median [IQR])15.00 [13.00, 16.00]
Gender (% male)22 753 (44.1)
Race or ethnicity (%)
 White16 367 (31.8)
 Hispanic12 069 (23.4)
 Black or African American9241 (17.9)
 Asian5812 (11.3)
 Other499 (1.0)
 Missing7557 (14.7)
High poverty (%)
 No23 968 (46.5)
 Yes27 363 (53.1)
 Not reported214 (0.4)
Rural (%)
 No47 881 (92.9)
 Yes3606 (7.0)
 Not reported58 (0.1)
HPSA (%)
 No597 (1.2)
 Yes50 894 (98.7)
 Not reported54 (0.1)
B
Entire Sample (n)77 741
Tooth type (%)
 Anterior11 272 (14.5)
 Molar55 788 (71.8)
 Premolar10 681 (13.7)
Time until restoration (%)
 0–14 days28 489 (36.6)
 15–59 days17 248 (22.2)
 60 + days17 391 (22.4)
 Never placed14 613 (18.8)
Restoration type (%)
 Amalgam3845 (4.9)
 Buildups37 827 (48.7)
 Composite7472 (9.6)
 Cuspal13 984 (18.0)
 Never placed14 613 (18.8)
FIGURE 1

Hazard ratio forest plot based on the Cox proportional hazards model

Survival rates of initial NSRCTs were evaluated at 1 year, 3 years, and 5 years. The median follow-up period in this cohort was 44 months [IQR: 26–79; range: 12–158]. The median follow-up time was 42 months [IQR: 25–73] for initial NSRCT procedures on teeth that did not experience an untoward event and 75 months [IQR: 45–113] for teeth with initial NSRCTs that did experience an untoward event. At 1 year, 76,171 primary root canal therapies could be evaluated, with a survival rate of 98% [95% CI: 97.9–98.1]. At 3 years, 44 052 procedures could be evaluated, with a survival rate of 92% [95% CI: 91.9 92.3]. At 5 years, 23 080 procedures could be evaluated, with a survival rate of 88% [95% CI: 87.2 87.8] (Table 2, Figure 2). Tooth retention was 98.3% at 1 year, 93.1% at 3 years, and 89.2% at 5 years.
TABLE 2

Summary of survival estimates of initial NSRCT

Time (year)GroupCategoryCasesSurvival distributionfunction estimateLower 95% confidenceintervalUpper 95% confidenceinterval
1Overall76 3780.9800.9790.981
Tooth typeAnterior11 1660.9890.9870.991
Premolar10 5350.9850.9830.987
Molar54 6770.9770.9760.978
Time to permanent restoration0–14 days28 2690.9910.9900.992
15–59 days17 1250.9920.9900.993
60 + days17 2160.9880.9870.990
never placed93620.9330.9290.938
Restoration typeAmalgam38080.9880.9840.991
Buildups37 5600.9920.9910.993
Composite73750.9850.9820.988
Cuspal13 8670.9910.9890.992
Never placed93620.9330.9290.938
3Overall44 0520.9210.9180.923
Tooth typeAnterior68850.9640.9600.967
Premolar59120.9440.9390.949
Molar31 2550.9070.9050.910
Time to permanent restoration0–14 days16 7370.9560.9530.959
15–59 days10 2970.9610.9580.965
60 + days10 6910.9470.9440.951
never placed63270.7670.7590.775
Restoration typeAmalgam25840.9440.9360.952
Buildups22 2650.9590.9560.961
Composite43030.9360.9300.943
Cuspal85730.9580.9540.962
Never placed63270.7670.7590.775
5Overall23 0800.8750.8710.878
Tooth typeAnterior36880.9430.9360.950
Premolar29670.9120.9040.919
Molar16 4250.8540.8500.858
Time to permanent restoration0–14 days86900.9160.9120.921
15–59 days54930.9240.9190.930
60 + days59410.9030.8980.909
never placed29560.6910.6800.701
Restoration typeAmalgam16350.8930.8810.905
Buildups11 6970.9190.9150.923
Composite22790.8970.8880.906
Cuspal45130.9200.9130.925
Never placed29560.6910.6800.701
FIGURE 2

Collective survival of initial NSRCT over the study period (the Kaplan–Meier survival estimates)

A sensitivity analysis on the Kaplan–Meier survival estimates and adjusted hazard ratios, which removed all eligibility-censored cases, did not result in any statistically or clinically significant differences in treatment outcomes. Clustering teeth at the person level yielded slightly more conservative standard error estimates (Tables 2 and 3), with no clinically meaningful differences compared with regular, nonrobust standard errors.
TABLE 3

Hazard ratio estimates from univariable and multivariable Cox regression models with robust standard errors

N (%)HR, univariable model(95% CI and p-value)HR, multivariable model(95% CI and p-value)
Age16–1826 501 (42.0)
13–1524 224 (38.4)1.25 (1.16–1.34, p < .001)1.20 (1.11–1.29, p < .001)
10–1210 509 (16.6)1.61 (1.49–1.74, p < .001)1.44 (1.32–1.57, p < .001)
6–91894 (3.0)2.57 (2.26–2.91, p < .001)2.18 (1.91–2.50, p < .001)
Tooth typeMolar44 492 (70.5)
Premolar8841 (14.0)0.58 (0.53–0.65, p < .001)0.65 (0.58–0.72, p < .001)
Anterior9795 (15.5)0.58 (0.52–0.63, p < .001)0.58 (0.51–0.66, p < .001)
Time to restoration0–14 days28 489 (45.1)
15–59 days17 248 (27.3)0.92 (0.86–0.99, p = .025)0.89 (0.83–0.96, p = .004)
60 + days17 391 (27.5)1.14 (1.07–1.22, p < .001)1.10 (1.02–1.18, p = .010)
Restoration typeCuspal13 984 (22.2)
Composite7472 (11.8)1.33 (1.20–1.47, p < .001)1.36 (1.22–1.51, p < .001)
Buildups37 827 (59.9)1.01 (0.94–1.09, p = .740)1.06 (0.98–1.15, p = .154)
Amalgam3845 (6.1)1.32 (1.17–1.48, p < .001)1.17 (1.04–1.33, p = .010)

Tooth type

The case distribution consisted of 11 272 (15%) anterior teeth, 10 681 (14%) premolars, and 55 788 (72%) molars (Table 1). There was a significant difference in survival based on tooth type (p < .0001) (Figure 1). Compared with molars, premolar (aHR = 0.65 (p < .001)) and anterior (aHR = 0.58 (p = .007)) teeth both had a reduced risk of failure, controlling for the presence of a permanent restoration (Figure 1). The survival of initial NSRCT for all anterior teeth was 99% [95% CI: 98.7–99.1] at 12 months; 96% [95% CI: 96.0–96.7] at 36 months; and 94% [95% CI: 93.8–94.8] at 60 months. For all treated premolars, the survival of initial NSRCT at 12 months was 99% [98.3–98.7]; at 36 months, 94% [93.9–94.9]; and at 60 months, 91% [90.5–91.9]. For all molars, the survival of initial NSRCT at 12 months was 98% [97.6–97.8]; 36 months, 91% [90.5–91.0]; and 60 months, 85% [85.0–85.7] (Table 2, Figure 3).
FIGURE 3

Survival of initial NSRCTs by tooth type (the Kaplan–Meier survival estimates)

Coronal restoration

Teeth without the placement of a permanent restoration after initial NSRCT represented 14 613 (19%) of all cases (Table 1). There was a statistically significant difference in survival, at every time point, when permanent restorations were not placed (p < .001) (Table 2). The mean time from the completion of initial NSRCT to the placement of a permanent restoration was 93 days, with a median of 20 days (range: 0 days–158 months). There was a significant difference in procedural survival by time until restoration, but the association was not monotonic (Figure 1). The majority of teeth with permanent restorations did not have cuspal coverage (68%) (Table 1). Compared to teeth with cuspal coverage, the teeth with composite or amalgams as final restorations, but without cuspal protection, had a greater risk of failure (aHR = 1.36 (p < .001) or aHR = 1.17 (p = .010)) (Figure 1).

Untoward events

For initial NSRCTs that did not have the survival rate of at least 1 year, the untoward events included surgical retreatment (n = 85, 0.1%), nonsurgical retreatment (n = 142, 0.18%), or extraction (n = 1157, 1.49%). For all of the treated teeth (n = 26 245) of patients continuously enrolled in Medicaid for at least five years, the incidence of surgical retreatment was 173 (0.66%); nonsurgical retreatment, 406 (1.6%); and extraction, 3065 (12%). Eighty-four teeth (0.32%) underwent endodontic retreatment (nonsurgical or surgical) prior to extraction. The number and type of untoward events per year in patients followed at least 5 years are shown in Table 4. Untoward events by tooth type were analyzed for this subset of cases. Of the treated anterior teeth (n = 3874, 15%), the incidence of nonsurgical retreatment was 51 (1.3%); surgical retreatment, 79 (2.0%); and extraction, 123 (3.2%). Of the treated premolars (n = 3235, 12%), 41 (1.3%) underwent nonsurgical retreatment; 18 (0.6%), surgical retreatment; and 263 (8.1%), extraction. Of the treated molars (n = 19,136; 72.9%), the incidence of nonsurgical retreatment was 314 (1.6%); surgical retreatment, 76 (0.4%); and extraction, 2679 (14%).
TABLE 4

Number of untoward events for subjects with a 5 years minimum follow-up

Months0–1212–2425–3637–4849–60Cumulativetotal (%)
Overall (n = 26 245)
 Apicoectomy, n(%)37 (0.14)30 (0.11)36 (0.14)32 (0.12)38 (0.14)173 (0.66)
 Extraction, n(%)509 (1.94)773 (2.95)734 (2.8)566 (2.16)483 (1.84)3065 (11.68)
 Retreat, n(%)52 (0.2)86 (0.33)86 (0.33)94 (0.36)88 (0.34)406 (1.55)
Anterior (n = 3874)
 Apicoectomy, n(%)22 (0.57)13 (0.34)18 (0.46)10 (0.26)16 (0.41)79 (2.04)
 Extraction, n(%)20 (0.52)32 (0.83)30 (0.77)21 (0.54)20 (0.52)123 (3.18)
 Retreat, n(%)8 (0.21)11 (0.28)12 (0.31)7 (0.18)13 (0.34)51 (1.32)
Premolar (n = 3 235)
 Apicoectomy, n(%)7 (0.22)3 (0.09)3 (0.09)3 (0.09)2 (0.06)18 (0.56)
 Extraction, n(%)45 (1.39)69 (2.13)60 (1.85)47 (1.45)42 (1.3)263 (8.13)
 Retreat, n(%)6 (0.19)12 (0.37)9 (0.28)6 (0.19)8 (0.25)41 (1.27)
Molar (n = 19,136)
 Apicoectomy, n(%)8 (0.04)14 (0.07)15 (0.08)19 (0.1)20 (0.1)76 (0.4)
 Extraction, n(%)444 (2.32)672 (3.51)644 (3.37)498 (2.6)421 (2.2)2679 (14)
 Retreat, n(%)38 (0.2)63 (0.33)65 (0.34)81 (0.42)67 (0.35)314 (1.64)

DISCUSSION

Recent increases in dental care utilization by children in the United States are largely a result of the passage of the Affordable Care Act (ACA) and coincide with increased government spending on dental care.[14] As state and federal governments continually re-evaluate their commitments to dental spending, the impact and outcomes of various aspects of dental treatment should be assessed for these large populations undergoing care provided in communities.[8] This study analyzed the outcomes of initial NSRCT of over 50 000 children (and over 77 000 permanent teeth) who were continuously enrolled in the New York State Medicaid for at least 1 year. The survival rate of initial NSRCT was 98% at 1 year, 92% at 3 years, and 88% at 5 years for those with a long enough follow-up. At 10 years, 6422 teeth could be evaluated and the survival rate was 80.3% [95% CI: 79.8–80.8]. The 10 years data were not included in the results due to the comparatively small sample size to those reported at 1, 3, and 5 years (76 171; 44 052; and 23 080 teeth, respectively). The subset cohort with at least 5 years of follow-up showed tooth retention of 89% at 5 years. In comparison with other epidemiological studies of root canal therapy outcomes in US populations, we found generally lower procedural survival and tooth retention rates five and ten years after treatment.[3,4,6,7] When assessing the clinical significance of this study and contextualizing its findings, several things should be considered: (1) the patient population and (2) reported clinical trends. First, it is important to note that the patient population in this study differs from previous studies with regard to patient age and type of insurance coverage. For example, the median patient age in this study was 15 years. In the previously referenced epidemiological studies of root canal therapy outcomes in US populations, the median age of the patients was over 40 years[3,7] or not reported.[4,6] Further, the patient population in this study had public-payer dental coverage (Medicaid). All of the previously mentioned studies[3,4,6,7] report the outcomes of patients covered by a single private-payer dental insurance (Delta Dental). Future research into the outcomes of endodontic treatment in a paediatric patient cohort with a private-payer dental insurance would allow for a more direct comparison of outcomes between paediatric and adult populations and highlight potential disparities in treatment outcomes between beneficiaries of public-payer and private-payer dental benefits. A comparison of the outcomes of endodontic treatment in both paediatric and adult cohorts insured by a public-payer dental insurance would be more difficult, as many states do not cover endodontic treatment for Medicaid-eligible adults.[26] In New York State, NSRCTs of anterior and premolar teeth are covered.[27] Molar root canal therapy in the overwhelming majority of this study's sample (71.8%), however, is not covered for Medicaid beneficiaries aged 21 years and older.[27] Exceptions are made when tooth extraction would be medically contraindicated or the tooth is a critical abutment for an existing serviceable prosthesis provided by the New York State Medicaid program.[27] Second, although the overall long-term survival rates in this study were lower than the outcomes reported in other epidemiological studies in US populations, several clinical trends corresponded. Consistent with previous studies, molars had the poorest outcomes and extraction was the most common type of untoward event, immediately following the failure of the initial nonsurgical root canal therapy.[3,4,28] Our findings on permanent restorations coincide with Lazarski et al, which state that teeth with no subsequent restoration after NSRCT had the lowest survival rates.[3] Further, similar to Salehrabi and Rotstein, we found that teeth restored with cuspal coverage had better outcomes than teeth without cuspal coverage after endodontic treatment.[4] Lastly, we found that time to final restoration influenced the survival rate of primary NSRCT, similar to Yee et al[7] The primary limitation of this study is one that applies to other outcome studies utilizing administrative claims: the nonclinical nature of the data. It is possible that data are missing resulting from events that may not be captured in the claims, such as out-of-pocket payments to providers who do not participate in Medicaid. This would result in an overstatement of successful outcomes. Additionally, incorrect coding may contribute to potential errors in the data. Another limitation related to dental claims specifically is the absence of diagnostic codes. The lack of diagnostic information results in the inability to evaluate prognostic predictors that impact endodontic treatment outcomes, including preoperative pulpal and periapical diagnosis, or reasons for treatment failure, such as recurrent decay, tooth fracture, tooth restorability, or quality of the initial endodontic treatment/coronal restoration.[2,29] The large sample size, however, allows us to draw broad conclusions in an important cohort to evaluate for its policy implications. This study is the first of its kind to explore survival rates of initial nonsurgical root canal therapy in a paediatric population in the United States and include a person-level analysis. The findings demonstrate that endodontic treatment maintains the permanent dentition in the long term. This is particularly important for paediatric patients who are limited with regard to tooth replacement options after compromised permanent teeth are extracted. Further, the findings reaffirm the importance of the final restoration as a continuum of endodontic treatment. Clear opportunities for improvement in the treatment of this paediatric population are apparent and include the following: (1) increased frequency in the placement of permanent restorations after root canal therapy; (2) decreased time to the placement of definitive restorations after the completion of endodontic treatment; and (3) increased use of cuspal coverage, when definitive restorations are placed.
  16 in total

Review 1.  A systematic review of single crowns on endodontically treated teeth.

Authors:  A F Stavropoulou; P T Koidis
Journal:  J Dent       Date:  2007-09-05       Impact factor: 4.379

2.  A decade in dental care utilization among adults and children (2001-2010).

Authors:  Marko Vujicic; Kamyar Nasseh
Journal:  Health Serv Res       Date:  2013-12-03       Impact factor: 3.402

3.  First untoward events and reasons for tooth extraction after nonsurgical endodontic treatment in Taiwan.

Authors:  Shih-Chung Chen; Ling-Huey Chueh; Chuhsing Kate Hsiao; Hsin-Ping Wu; Chun-Pin Chiang
Journal:  J Endod       Date:  2008-04-25       Impact factor: 4.171

4.  Failure of endodontically treated teeth: classification and evaluation.

Authors:  D E Vire
Journal:  J Endod       Date:  1991-07       Impact factor: 4.171

5.  Outcomes of Primary Endodontic Therapy Provided by Endodontic Specialists Compared with Other Providers.

Authors:  Jacob C Burry; Sheila Stover; Frederick Eichmiller; Pradeep Bhagavatula
Journal:  J Endod       Date:  2016-03-19       Impact factor: 4.171

6.  Survival Rates of Teeth with Primary Endodontic Treatment after Core/Post and Crown Placement.

Authors:  Kandace Yee; Pradeep Bhagavatula; Sheila Stover; Frederick Eichmiller; Lance Hashimoto; Scott MacDonald; Gordon Barkley
Journal:  J Endod       Date:  2017-12-08       Impact factor: 4.171

Review 7.  Review: behaviour management techniques in paediatric dentistry.

Authors:  J F Roberts; M E J Curzon; G Koch; L C Martens
Journal:  Eur Arch Paediatr Dent       Date:  2010-08

8.  Endodontic treatment outcomes in a large patient population in the USA: an epidemiological study.

Authors:  Robert Salehrabi; Ilan Rotstein
Journal:  J Endod       Date:  2004-12       Impact factor: 4.171

9.  Epidemiological evaluation of the outcomes of nonsurgical root canal treatment in a large cohort of insured dental patients.

Authors:  M P Lazarski; W A Walker; C M Flores; W G Schindler; K M Hargreaves
Journal:  J Endod       Date:  2001-12       Impact factor: 4.171

Review 10.  Dental fear/anxiety and dental behaviour management problems in children and adolescents: a review of prevalence and concomitant psychological factors.

Authors:  Gunilla Klingberg; Anders G Broberg
Journal:  Int J Paediatr Dent       Date:  2007-11       Impact factor: 3.455

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  1 in total

1.  Epidemiological evaluation of the outcomes of initial root canal therapy in permanent teeth of a publicly insured paediatric population.

Authors:  Lorel E Burns; Kelly Terlizzi; Claudia Solis-Roman; Yinxiang Wu; Asgeir Sigurdsson; Heather T Gold
Journal:  Int J Paediatr Dent       Date:  2022-03-31       Impact factor: 3.264

  1 in total

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