| Literature DB >> 35000244 |
Lorel E Burns1, Kelly Terlizzi2, Claudia Solis-Roman2, Yinxiang Wu3, Asgeir Sigurdsson1, Heather T Gold3.
Abstract
BACKGROUND: Previously published epidemiological outcome studies of nonsurgical root canal therapy (NSRCT) in the United States utilize data only from a single, private dental insurer for adult populations. AIM: This study aimed to investigate the outcomes of initial NSRCT, performed on permanent teeth, in a publicly insured paediatric population.Entities:
Keywords: endodontics; medicaid; paediatric dentistry; root canal therapy; survival analysis; treatment outcomes
Mesh:
Year: 2022 PMID: 35000244 PMCID: PMC9272438 DOI: 10.1111/ipd.12953
Source DB: PubMed Journal: Int J Paediatr Dent ISSN: 0960-7439 Impact factor: 3.264
Description of study cohort (A. tooth level; B. patient level)
| A | |
|---|---|
| Patient sample ( | 51 545 |
| Age category (%) | |
| 6–9 | 2065 (4.0) |
| 10–12 | 10 039 (19.5) |
| 13–15 | 19 928 (38.7) |
| 16–18 | 19 513 (37.9) |
| Age (median [IQR]) | 15.00 [13.00, 16.00] |
| Gender (% male) | 22 753 (44.1) |
| Race or ethnicity (%) | |
| White | 16 367 (31.8) |
| Hispanic | 12 069 (23.4) |
| Black or African American | 9241 (17.9) |
| Asian | 5812 (11.3) |
| Other | 499 (1.0) |
| Missing | 7557 (14.7) |
| High poverty (%) | |
| No | 23 968 (46.5) |
| Yes | 27 363 (53.1) |
| Not reported | 214 (0.4) |
| Rural (%) | |
| No | 47 881 (92.9) |
| Yes | 3606 (7.0) |
| Not reported | 58 (0.1) |
| HPSA (%) | |
| No | 597 (1.2) |
| Yes | 50 894 (98.7) |
| Not reported | 54 (0.1) |
| B | |
| Entire Sample ( | 77 741 |
| Tooth type (%) | |
| Anterior | 11 272 (14.5) |
| Molar | 55 788 (71.8) |
| Premolar | 10 681 (13.7) |
| Time until restoration (%) | |
| 0–14 days | 28 489 (36.6) |
| 15–59 days | 17 248 (22.2) |
| 60 + days | 17 391 (22.4) |
| Never placed | 14 613 (18.8) |
| Restoration type (%) | |
| Amalgam | 3845 (4.9) |
| Buildups | 37 827 (48.7) |
| Composite | 7472 (9.6) |
| Cuspal | 13 984 (18.0) |
| Never placed | 14 613 (18.8) |
FIGURE 1Hazard ratio forest plot based on the Cox proportional hazards model
Summary of survival estimates of initial NSRCT
| Time (year) | Group | Category | Cases | Survival distribution | Lower 95% confidence | Upper 95% confidence |
|---|---|---|---|---|---|---|
| 1 | Overall | 76 378 | 0.980 | 0.979 | 0.981 | |
| Tooth type | Anterior | 11 166 | 0.989 | 0.987 | 0.991 | |
| Premolar | 10 535 | 0.985 | 0.983 | 0.987 | ||
| Molar | 54 677 | 0.977 | 0.976 | 0.978 | ||
| Time to permanent restoration | 0–14 days | 28 269 | 0.991 | 0.990 | 0.992 | |
| 15–59 days | 17 125 | 0.992 | 0.990 | 0.993 | ||
| 60 + days | 17 216 | 0.988 | 0.987 | 0.990 | ||
| never placed | 9362 | 0.933 | 0.929 | 0.938 | ||
| Restoration type | Amalgam | 3808 | 0.988 | 0.984 | 0.991 | |
| Buildups | 37 560 | 0.992 | 0.991 | 0.993 | ||
| Composite | 7375 | 0.985 | 0.982 | 0.988 | ||
| Cuspal | 13 867 | 0.991 | 0.989 | 0.992 | ||
| Never placed | 9362 | 0.933 | 0.929 | 0.938 | ||
| 3 | Overall | 44 052 | 0.921 | 0.918 | 0.923 | |
| Tooth type | Anterior | 6885 | 0.964 | 0.960 | 0.967 | |
| Premolar | 5912 | 0.944 | 0.939 | 0.949 | ||
| Molar | 31 255 | 0.907 | 0.905 | 0.910 | ||
| Time to permanent restoration | 0–14 days | 16 737 | 0.956 | 0.953 | 0.959 | |
| 15–59 days | 10 297 | 0.961 | 0.958 | 0.965 | ||
| 60 + days | 10 691 | 0.947 | 0.944 | 0.951 | ||
| never placed | 6327 | 0.767 | 0.759 | 0.775 | ||
| Restoration type | Amalgam | 2584 | 0.944 | 0.936 | 0.952 | |
| Buildups | 22 265 | 0.959 | 0.956 | 0.961 | ||
| Composite | 4303 | 0.936 | 0.930 | 0.943 | ||
| Cuspal | 8573 | 0.958 | 0.954 | 0.962 | ||
| Never placed | 6327 | 0.767 | 0.759 | 0.775 | ||
| 5 | Overall | 23 080 | 0.875 | 0.871 | 0.878 | |
| Tooth type | Anterior | 3688 | 0.943 | 0.936 | 0.950 | |
| Premolar | 2967 | 0.912 | 0.904 | 0.919 | ||
| Molar | 16 425 | 0.854 | 0.850 | 0.858 | ||
| Time to permanent restoration | 0–14 days | 8690 | 0.916 | 0.912 | 0.921 | |
| 15–59 days | 5493 | 0.924 | 0.919 | 0.930 | ||
| 60 + days | 5941 | 0.903 | 0.898 | 0.909 | ||
| never placed | 2956 | 0.691 | 0.680 | 0.701 | ||
| Restoration type | Amalgam | 1635 | 0.893 | 0.881 | 0.905 | |
| Buildups | 11 697 | 0.919 | 0.915 | 0.923 | ||
| Composite | 2279 | 0.897 | 0.888 | 0.906 | ||
| Cuspal | 4513 | 0.920 | 0.913 | 0.925 | ||
| Never placed | 2956 | 0.691 | 0.680 | 0.701 |
FIGURE 2Collective survival of initial NSRCT over the study period (the Kaplan–Meier survival estimates)
Hazard ratio estimates from univariable and multivariable Cox regression models with robust standard errors
| HR, univariable model | HR, multivariable model | |||
|---|---|---|---|---|
| Age | 16–18 | 26 501 (42.0) | – | – |
| 13–15 | 24 224 (38.4) | 1.25 (1.16–1.34, | 1.20 (1.11–1.29, | |
| 10–12 | 10 509 (16.6) | 1.61 (1.49–1.74, | 1.44 (1.32–1.57, | |
| 6–9 | 1894 (3.0) | 2.57 (2.26–2.91, | 2.18 (1.91–2.50, | |
| Tooth type | Molar | 44 492 (70.5) | – | – |
| Premolar | 8841 (14.0) | 0.58 (0.53–0.65, | 0.65 (0.58–0.72, | |
| Anterior | 9795 (15.5) | 0.58 (0.52–0.63, | 0.58 (0.51–0.66, | |
| Time to restoration | 0–14 days | 28 489 (45.1) | – | – |
| 15–59 days | 17 248 (27.3) | 0.92 (0.86–0.99, | 0.89 (0.83–0.96, | |
| 60 + days | 17 391 (27.5) | 1.14 (1.07–1.22, | 1.10 (1.02–1.18, | |
| Restoration type | Cuspal | 13 984 (22.2) | – | – |
| Composite | 7472 (11.8) | 1.33 (1.20–1.47, | 1.36 (1.22–1.51, | |
| Buildups | 37 827 (59.9) | 1.01 (0.94–1.09, | 1.06 (0.98–1.15, | |
| Amalgam | 3845 (6.1) | 1.32 (1.17–1.48, | 1.17 (1.04–1.33, |
FIGURE 3Survival of initial NSRCTs by tooth type (the Kaplan–Meier survival estimates)
Number of untoward events for subjects with a 5 years minimum follow-up
| Months | 0–12 | 12–24 | 25–36 | 37–48 | 49–60 | Cumulative |
|---|---|---|---|---|---|---|
| Overall ( | ||||||
| Apicoectomy, | 37 (0.14) | 30 (0.11) | 36 (0.14) | 32 (0.12) | 38 (0.14) | 173 (0.66) |
| Extraction, | 509 (1.94) | 773 (2.95) | 734 (2.8) | 566 (2.16) | 483 (1.84) | 3065 (11.68) |
| Retreat, | 52 (0.2) | 86 (0.33) | 86 (0.33) | 94 (0.36) | 88 (0.34) | 406 (1.55) |
| Anterior ( | ||||||
| Apicoectomy, | 22 (0.57) | 13 (0.34) | 18 (0.46) | 10 (0.26) | 16 (0.41) | 79 (2.04) |
| Extraction, | 20 (0.52) | 32 (0.83) | 30 (0.77) | 21 (0.54) | 20 (0.52) | 123 (3.18) |
| Retreat, | 8 (0.21) | 11 (0.28) | 12 (0.31) | 7 (0.18) | 13 (0.34) | 51 (1.32) |
| Premolar ( | ||||||
| Apicoectomy, | 7 (0.22) | 3 (0.09) | 3 (0.09) | 3 (0.09) | 2 (0.06) | 18 (0.56) |
| Extraction, | 45 (1.39) | 69 (2.13) | 60 (1.85) | 47 (1.45) | 42 (1.3) | 263 (8.13) |
| Retreat, | 6 (0.19) | 12 (0.37) | 9 (0.28) | 6 (0.19) | 8 (0.25) | 41 (1.27) |
| Molar ( | ||||||
| Apicoectomy, | 8 (0.04) | 14 (0.07) | 15 (0.08) | 19 (0.1) | 20 (0.1) | 76 (0.4) |
| Extraction, | 444 (2.32) | 672 (3.51) | 644 (3.37) | 498 (2.6) | 421 (2.2) | 2679 (14) |
| Retreat, | 38 (0.2) | 63 (0.33) | 65 (0.34) | 81 (0.42) | 67 (0.35) | 314 (1.64) |