Literature DB >> 34996848

Common idiopathic pulmonary fibrosis risk variants are associated with hypersensitivity pneumonitis.

Haruhiko Furusawa1,2, Anna L Peljto1, Avram D Walts1, Jonathan Cardwell1, Philip L Molyneaux3, Joyce S Lee1, Evans R Fernández Pérez4, Paul J Wolters5, Ivana V Yang1, David A Schwartz6.   

Abstract

A subset of patients with hypersensitivity pneumonitis (HP) develop lung fibrosis that is clinically similar to idiopathic pulmonary fibrosis (IPF). To address the aetiological determinants of fibrotic HP, we investigated whether the common IPF genetic risk variants were also relevant in study subjects with fibrotic HP. Our findings indicate that common genetic variants in TERC, DSP, MUC5B and IVD were significantly associated with fibrotic HP. These findings provide support for a shared etiology and pathogenesis between fibrotic HP and IPF. © Author(s) (or their employer(s)) 2022. No commercial re-use. See rights and permissions. Published by BMJ.

Entities:  

Keywords:  hypersensitivity pneumonitis

Mesh：

Year:  2022        PMID： 34996848      PMCID： PMC9013199          DOI： 10.1136/thoraxjnl-2021-217693

Source DB:  PubMed          Journal:  Thorax        ISSN： 0040-6376            Impact factor:   9.102


  17 in total

Review 1.  Hypersensitivity pneumonitis.

Authors:  Ulrich Costabel; Yasunari Miyazaki; Annie Pardo; Dirk Koschel; Francesco Bonella; Paolo Spagnolo; Josune Guzman; Christopher J Ryerson; Moises Selman
Journal:  Nat Rev Dis Primers       Date:  2020-08-06       Impact factor: 52.329

2.  Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis.

Authors:  Brian D Hobbs; Kim de Jong; Maxime Lamontagne; Yohan Bossé; Nick Shrine; María Soler Artigas; Louise V Wain; Ian P Hall; Victoria E Jackson; Annah B Wyss; Stephanie J London; Kari E North; Nora Franceschini; David P Strachan; Terri H Beaty; John E Hokanson; James D Crapo; Peter J Castaldi; Robert P Chase; Traci M Bartz; Susan R Heckbert; Bruce M Psaty; Sina A Gharib; Pieter Zanen; Jan W Lammers; Matthijs Oudkerk; H J Groen; Nicholas Locantore; Ruth Tal-Singer; Stephen I Rennard; Jørgen Vestbo; Wim Timens; Peter D Paré; Jeanne C Latourelle; Josée Dupuis; George T O'Connor; Jemma B Wilk; Woo Jin Kim; Mi Kyeong Lee; Yeon-Mok Oh; Judith M Vonk; Harry J de Koning; Shuguang Leng; Steven A Belinsky; Yohannes Tesfaigzi; Ani Manichaikul; Xin-Qun Wang; Stephen S Rich; R Graham Barr; David Sparrow; Augusto A Litonjua; Per Bakke; Amund Gulsvik; Lies Lahousse; Guy G Brusselle; Bruno H Stricker; André G Uitterlinden; Elizabeth J Ampleford; Eugene R Bleecker; Prescott G Woodruff; Deborah A Meyers; Dandi Qiao; David A Lomas; Jae-Joon Yim; Deog Kyeom Kim; Iwona Hawrylkiewicz; Pawel Sliwinski; Megan Hardin; Tasha E Fingerlin; David A Schwartz; Dirkje S Postma; William MacNee; Martin D Tobin; Edwin K Silverman; H Marike Boezen; Michael H Cho
Journal:  Nat Genet       Date:  2017-02-06       Impact factor: 38.330

3.  Rare Protein-Altering Telomere-related Gene Variants in Patients with Chronic Hypersensitivity Pneumonitis.

Authors:  Brett Ley; Dara G Torgerson; Justin M Oldham; Ayodeji Adegunsoye; Shuo Liu; Jie Li; Brett M Elicker; Travis S Henry; Jeffrey A Golden; Kirk D Jones; Amy Dressen; Brian L Yaspan; Joseph R Arron; Imre Noth; Thomas J Hoffmann; Paul J Wolters
Journal:  Am J Respir Crit Care Med       Date:  2019-11-01       Impact factor: 21.405

Review 4.  Moving beyond genetics: is FAM13A a major biological contributor in lung physiology and chronic lung diseases?

Authors:  Harriet Corvol; Craig A Hodges; Mitchell L Drumm; Loïc Guillot
Journal:  J Med Genet       Date:  2014-08-27       Impact factor: 6.318

5.  A multidimensional index and staging system for idiopathic pulmonary fibrosis.

Authors:  Brett Ley; Christopher J Ryerson; Eric Vittinghoff; Jay H Ryu; Sara Tomassetti; Joyce S Lee; Venerino Poletti; Matteo Buccioli; Brett M Elicker; Kirk D Jones; Talmadge E King; Harold R Collard
Journal:  Ann Intern Med       Date:  2012-05-15       Impact factor: 25.391

6.  CT Imaging Phenotypes of Pulmonary Fibrosis in the MUC5B Promoter Site Polymorphism.

Authors:  Jonathan H Chung; Anna L Peljto; Ashish Chawla; Janet L Talbert; David F McKean; Byung-Hak Rho; Tasha E Fingerlin; Marvin I Schwarz; David A Schwartz; David A Lynch
Journal:  Chest       Date:  2016-01-13       Impact factor: 9.410

7.  The MUC5B promoter risk allele for idiopathic pulmonary fibrosis predisposes to asbestosis.

Authors:  Mark G J P Platenburg; Ivo A Wiertz; Joanne J van der Vis; Bruno Crestani; Raphael Borie; Philippe Dieude; Caroline Kannengiesser; Jacobus A Burgers; Jan C Grutters; Coline H M van Moorsel
Journal:  Eur Respir J       Date:  2020-04-30       Impact factor: 16.671

8.  Diagnosis and Evaluation of Hypersensitivity Pneumonitis: CHEST Guideline and Expert Panel Report.

Authors:  Evans R Fernández Pérez; William D Travis; David A Lynch; Kevin K Brown; Kerri A Johannson; Moisés Selman; Jay H Ryu; Athol U Wells; Yuh-Chin Tony Huang; Carlos A C Pereira; Mary-Beth Scholand; Ana Villar; Naohiko Inase; Richard B Evans; Stephen A Mette; Lindsy Frazer-Green
Journal:  Chest       Date:  2021-04-20       Impact factor: 9.410

9.  Molecular markers of telomere dysfunction and senescence are common findings in the usual interstitial pneumonia pattern of lung fibrosis.

Authors:  Joyce S Lee; Janet La; Sara Aziz; Evgenia Dobrinskikh; Robert Brownell; Kirk D Jones; Natalia Achtar-Zadeh; Gary Green; Brett M Elicker; Jeffrey A Golden; Michael A Matthay; Jasleen Kukreja; David A Schwartz; Paul J Wolters
Journal:  Histopathology       Date:  2021-04-14       Impact factor: 7.778

10.  The MUC5B promoter polymorphism and telomere length in patients with chronic hypersensitivity pneumonitis: an observational cohort-control study.

Authors:  Brett Ley; Chad A Newton; Isabel Arnould; Brett M Elicker; Travis S Henry; Eric Vittinghoff; Jeffrey A Golden; Kirk D Jones; Kiran Batra; Jose Torrealba; Christine Kim Garcia; Paul J Wolters
Journal:  Lancet Respir Med       Date:  2017-06-22       Impact factor: 30.700
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  2 in total

1.  Muc5b plays a role in the development of inflammation and fibrosis in hypersensitivity pneumonitis induced by Saccharopolyspora rectivirgula.

Authors:  Tsukasa Okamoto; Evgenia Dobrinskikh; Corinne E Hennessy; Naoko Liu; Marvin I Schwarz; Christopher M Evans; Andrew P Fontenot; Ivana V Yang; David A Schwartz
Journal:  Am J Physiol Lung Cell Mol Physiol       Date:  2022-07-26       Impact factor: 6.011

2.  Single Nucleotide Polymorphisms (SNP) and SNP-SNP Interactions of the Surfactant Protein Genes Are Associated With Idiopathic Pulmonary Fibrosis in a Mexican Study Group; Comparison With Hypersensitivity Pneumonitis.

Authors:  Ata Abbasi; Chixiang Chen; Chintan K Gandhi; Rongling Wu; Annie Pardo; Moises Selman; Joanna Floros
Journal:  Front Immunol       Date:  2022-06-02       Impact factor: 8.786
  2 in total

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