Literature DB >> 3499398

Effect of complement depletion on anticapsular-antibody-mediated immunity to experimental infection with Haemophilus influenzae type b.

J R Schreiber1, C J Basker, G R Siber.   

Abstract

Antibody to the capsular polysaccharide of Haemophilus influenzae type b (Hib) was not protective in infant rats depleted of complement by cobra venom factor (CoVF) even when serum antibody levels were many times the minimum protective level. Partial protection from Hib infection was achieved in CoVF-treated rats only if they were passively hyperimmunized with large doses of immunoglobulin G Hib capsular polysaccharide antibody. In addition, nonimmune CoVF-treated rats had higher mortality and blood bacterial density than nonimmune rats with intact complement systems.

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Year:  1987        PMID: 3499398      PMCID: PMC259984          DOI: 10.1128/iai.55.11.2830-2833.1987

Source DB:  PubMed          Journal:  Infect Immun        ISSN: 0019-9567            Impact factor:   3.441


  21 in total

1.  Participation of complement in the nonimmune host defense against experimental Haemophilus influenzae type b septicemia and meningitis.

Authors:  F J Crosson; J A Winkelstein; E R Moxon
Journal:  Infect Immun       Date:  1976-10       Impact factor: 3.441

2.  Separation of serum bactericidal and opsonizing activities for Haemophilus influenzae type b.

Authors:  S L Newman; B Waldo; R B Johnston
Journal:  Infect Immun       Date:  1973-09       Impact factor: 3.441

3.  Characterization of human antibody to polyribophosphate, the capsular antigen of Hemophilus influenzae, type B.

Authors:  R B Johnston; P Anderson; F S Rosen; D H Smith
Journal:  Clin Immunol Immunopathol       Date:  1973-01

4.  Quantitative measurement of "natural" and immunization-induced Haemophilus influenzae type b capsular polysaccharide antibodies.

Authors:  J B Robbins; J C Parke; R Schneerson; J K Whisnant
Journal:  Pediatr Res       Date:  1973-03       Impact factor: 3.756

5.  A simplified method for cyanogen bromide activation of agarose for affinity chromatography.

Authors:  S C March; I Parikh; P Cuatrecasas
Journal:  Anal Biochem       Date:  1974-07       Impact factor: 3.365

6.  Selective enzyme purification by affinity chromatography.

Authors:  P Cuatrecasas; M Wilchek; C B Anfinsen
Journal:  Proc Natl Acad Sci U S A       Date:  1968-10       Impact factor: 11.205

7.  Immunity to disease caused by Hemophilus influenzae type b. II. Specificity and some biologic characteristics of "natural," infection-acquired, and immunization-induced antibodies to the capsular polysaccharide of Hemophilus influenzae type b.

Authors:  R Schneerson; L P Rodrigues; J C Parke; J B Robbins
Journal:  J Immunol       Date:  1971-10       Impact factor: 5.422

8.  Antibody-independent and -dependent opsonization of group B Streptococcus requires the first component of complement C1.

Authors:  N J Levy; D L Kasper
Journal:  Infect Immun       Date:  1985-07       Impact factor: 3.441

9.  Human serum activities against Hemophilus influenzae, type b.

Authors:  P Anderson; R B Johnston; D H Smith
Journal:  J Clin Invest       Date:  1972-01       Impact factor: 14.808

10.  Functional characterization of human IgG, IgM, and IgA antibody directed to the capsule of Haemophilus influenzae type b.

Authors:  J R Schreiber; V Barrus; K L Cates; G R Siber
Journal:  J Infect Dis       Date:  1986-01       Impact factor: 5.226

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  5 in total

1.  Two-component systems in Haemophilus influenzae: a regulatory role for ArcA in serum resistance.

Authors:  J A De Souza-Hart; W Blackstock; V Di Modugno; I B Holland; M Kok
Journal:  Infect Immun       Date:  2003-01       Impact factor: 3.441

2.  Outer membrane protein binding sites of complement component 3 during opsonization of Haemophilus influenzae.

Authors:  S V Hetherington; C C Patrick; E J Hansen
Journal:  Infect Immun       Date:  1993-12       Impact factor: 3.441

3.  Complement component 3 binding to Haemophilus influenzae type b in the presence of anticapsular and anti-outer membrane antibodies.

Authors:  S V Hetherington; C C Patrick
Journal:  Infect Immun       Date:  1992-01       Impact factor: 3.441

4.  Outer membrane protein D15 is conserved among Haemophilus influenzae species and may represent a universal protective antigen against invasive disease.

Authors:  S M Loosmore; Y P Yang; D C Coleman; J M Shortreed; D M England; M H Klein
Journal:  Infect Immun       Date:  1997-09       Impact factor: 3.441

5.  Use of hybridoma immunoglobulin switch variants in the analysis of the protective properties of anti-lipopolysaccharide antibodies in Escherichia coli K1 infection.

Authors:  S Pelkonen; G Pluschke
Journal:  Immunology       Date:  1989-10       Impact factor: 7.397

  5 in total

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