Jing Li1,2, Shengsheng Wei1,2, Yaohua Zhang2, Dan Yang2, Zhen Tian2, Jing Du2, Yong Li2, Jianguo Liu2, Yan Wang3,4. 1. Clinical College of Ophthalmology, Tianjin Medical University, Tianjin, China. 2. Shaanxi Eye Hospital, Xi'an People's Hospital (Xi'an Fourth Hospital), Affiliated Guangren Hospital, School of Medicine, Xi'an Jiaotong University, Xi'an, China. 3. Clinical College of Ophthalmology, Tianjin Medical University, Tianjin, China. wangyan7143@vip.sina.com. 4. Tianjin Eye Institute, Tianjin Key Lab of Ophthalmology and Visual Science, Tianjin Eye Hospital, No 4. Gansu Road, He-ping District, Tianjin, 300020, China. wangyan7143@vip.sina.com.
Abstract
PURPOSE: To investigate the changes in posterior corneal elevations (PCEs) in the circular areas and local points after corneal collagen cross-linking (CXL) for the treatment of keratoconus. METHODS: Method 1 divided the cornea into 0-2, 2-4, 4-6, and 6-8 mm regions centering on the apex. Method 2 obtained other 34 PCE values of local point that were identified on the nasal, supra-nasal, sub-nasal, superior, inferior, temporal, supra-temporal, and sub-temporal sides of the circle with diameters of 2, 4, 6, and 8 mm, and the apex and thinnest point. RESULTS: Method 1 showed a forward displacement of PCE at 1 month after CXL and then a backward displacement at 3 months. In Method 2, the points on the temporal side of 2 mm and 4 mm showed the same trend. The backward displacements of PCE on the temporal side of 2 mm at 6 months and on the temporal side of 4 mm at 12 months after CXL were both statistically different than those at 1 month after CXL (P < 0.05). No significant forward displacement of PCE was found in all local points in different quadrants at 1 year after CXL. CONCLUSION: The PCEs in circular areas and characteristic points of different diameters in keratoconic eyes after CXL change with time. Local point assessment of the PCE is more clinically significant. In points selected in different quadrants of the cornea, the change in temporal points was more significant after CXL.
PURPOSE: To investigate the changes in posterior corneal elevations (PCEs) in the circular areas and local points after corneal collagen cross-linking (CXL) for the treatment of keratoconus. METHODS: Method 1 divided the cornea into 0-2, 2-4, 4-6, and 6-8 mm regions centering on the apex. Method 2 obtained other 34 PCE values of local point that were identified on the nasal, supra-nasal, sub-nasal, superior, inferior, temporal, supra-temporal, and sub-temporal sides of the circle with diameters of 2, 4, 6, and 8 mm, and the apex and thinnest point. RESULTS: Method 1 showed a forward displacement of PCE at 1 month after CXL and then a backward displacement at 3 months. In Method 2, the points on the temporal side of 2 mm and 4 mm showed the same trend. The backward displacements of PCE on the temporal side of 2 mm at 6 months and on the temporal side of 4 mm at 12 months after CXL were both statistically different than those at 1 month after CXL (P < 0.05). No significant forward displacement of PCE was found in all local points in different quadrants at 1 year after CXL. CONCLUSION: The PCEs in circular areas and characteristic points of different diameters in keratoconic eyes after CXL change with time. Local point assessment of the PCE is more clinically significant. In points selected in different quadrants of the cornea, the change in temporal points was more significant after CXL.
Authors: Dalal Asri; David Touboul; Pierre Fournié; Florence Malet; Caroline Garra; Anne Gallois; François Malecaze; Joseph Colin Journal: J Cataract Refract Surg Date: 2011-12 Impact factor: 3.351
Authors: F Cifariello; M Minicucci; F Di Renzo; D Di Taranto; G Coclite; S Zaccaria; S De Turris; C Costagliola Journal: J Ophthalmol Date: 2018-07-29 Impact factor: 1.909